2G0B
| The structure of FeeM, an N-acyl amino acid synthase from uncultured soil microbes | Descriptor: | FeeM, N-DODECANOYL-L-TYROSINE | Authors: | Van Wagoner, R.M, Clardy, J. | Deposit date: | 2006-02-11 | Release date: | 2006-09-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | FeeM, an N-Acyl Amino Acid Synthase from an Uncultured Soil Microbe: Structure, Mechanism, and Acyl Carrier Protein Binding. Structure, 14, 2006
|
|
6VGZ
| 2.25 A resolution structure of MERS 3CL protease in complex with inhibitor 6d | Descriptor: | N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-N~2~-({[trans-4-(propan-2-yl)cyclohexyl]oxy}carbonyl)-L-leucinamide, Orf1a protein | Authors: | Lovell, S, Battaile, K.P, Kashipathy, M.M, Rathnayake, A.D, Zheng, J, Kim, Y, Nguyen, H.N, Chang, K.O, Groutas, W.C. | Deposit date: | 2020-01-09 | Release date: | 2020-08-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med, 12, 2020
|
|
6VGU
| |
2GGX
| |
6UUF
| Crystal structure of a Nudix Hydrolase from M. Smegmatis, RenU | Descriptor: | Nudix Hydrolase, RenU | Authors: | Wright, K.M, Yoder, J, Shoemaker, S, Hernandez, A, Iheanacho, A, Marques, I, Amzel, M.L, Gabelli, S.B. | Deposit date: | 2019-10-30 | Release date: | 2021-05-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of RenU To Be Published
|
|
3Q50
| |
1RHU
| CRYSTAL STRUCTURE OF THE COMPLEX OF CASPASE-3 WITH A 5,6,7 TRICYCLIC PEPTIDOMIMETIC INHIBITOR | Descriptor: | (3S)-3-[({(2S)-5-[(N-ACETYL-L-ALPHA-ASPARTYL)AMINO]-4-OXO-1,2,4,5,6,7-HEXAHYDROAZEPINO[3,2,1-HI]INDOL-2-YL}CARBONYL)AMINO]-5-(BENZYLSULFANYL)-4-OXOPENTANOIC ACID, Caspase-3 | Authors: | Becker, J.W, Rotonda, J, Soisson, S.M. | Deposit date: | 2003-11-14 | Release date: | 2004-05-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Reducing the Peptidyl Features of Caspase-3 Inhibitors: A Structural Analysis. J.Med.Chem., 47, 2004
|
|
2G15
| Structural Characterization of autoinhibited c-Met kinase | Descriptor: | activated met oncogene | Authors: | Wang, W, Marimuthu, A, Tsai, J, Kumar, A, Krupka, H.I, Zhang, C, Powell, B, Suzuki, Y, Nguyen, H, Tabrizizad, M, Luu, C, West, B.L. | Deposit date: | 2006-02-13 | Release date: | 2006-03-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase. Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
6URP
| |
1AXC
| HUMAN PCNA | Descriptor: | P21/WAF1, PCNA | Authors: | Gulbis, J.M, Kuriyan, J. | Deposit date: | 1997-10-14 | Release date: | 1998-01-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Cell(Cambridge,Mass.), 87, 1996
|
|
2LSP
| solution structures of BRD4 second bromodomain with NF-kB-K310ac peptide | Descriptor: | Bromodomain-containing protein 4, NF-kB-K310ac peptide | Authors: | Zhang, G, Liu, R, Zhong, Y, Plotnikov, A.N, Zhang, W, Rusinova, E, Gerona-Nevarro, G, Moshkina, N, Joshua, J, Chuang, P.Y, Ohlmeyer, M, He, J, Zhou, M.-M. | Deposit date: | 2012-05-03 | Release date: | 2012-07-18 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Down-regulation of NF-kappa B transcriptional activity in HIV-associated kidney disease by BRD4 inhibition. J.Biol.Chem., 287, 2012
|
|
6URS
| Sleeping Beauty transposase PAI subdomain mutant - H19Y | Descriptor: | Sleeping Beauty transposase PAI subdomain | Authors: | Nesmelova, I.V, Leighton, G.O, Yan, C, Lustig, J, Corona, R.I, Guo, J.T, Ivics, Z. | Deposit date: | 2019-10-24 | Release date: | 2020-10-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | H19Y mutation in the primary DNA-recognition subdomain of the Sleeping Beauty transposase improves structural stability, transposon DNA-binding and transposition To Be Published
|
|
2F6U
| |
2FB0
| Crystal Structure of Conserved Protein of Unknown Function from Bacteroides thetaiotaomicron VPI-5482 at 2.10 A Resolution, Possible Oxidoreductase | Descriptor: | ACETATE ION, GLYCEROL, conserved hypothetical protein | Authors: | Nocek, B, Hatzos, C, Abdullah, J, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-08 | Release date: | 2006-01-24 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of conserved hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
at 2.10 resolution To be Published
|
|
2FB7
| |
6VI0
| Cryo-EM structure of VRC01.23 in complex with HIV-1 Env BG505 DS.SOSIP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 gp120, ... | Authors: | Gorman, J, Kwong, P.D. | Deposit date: | 2020-01-10 | Release date: | 2021-01-13 | Last modified: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention. Mabs, 13
|
|
2EW1
| Crystal Structure of Rab30 in complex with a GTP analogue | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-30 | Authors: | Wang, J, Shen, Y, Ismail, S, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC) | Deposit date: | 2005-11-01 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of RAB30 in complex with a GTP analogue To be Published
|
|
2ESC
| Crystal structure of a 40 KDa protective signalling protein from Bovine (SPC-40) at 2.1 A resolution | Descriptor: | Chitinase-3-like protein 1, alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Kumar, J, Ethayathulla, A.S, Srivastav, D.B, Sharma, S, Srinivasan, A, Singh, T.P. | Deposit date: | 2005-10-26 | Release date: | 2005-12-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a bovine secretory signalling glycoprotein (SPC-40) at 2.1 Angstrom resolution. Acta Crystallogr.,Sect.D, 62, 2006
|
|
2ET0
| The structure of a three-way DNA junction in complex with a metallo-supramolecular helicate reveals a new target for drugs | Descriptor: | 5'-D(*CP*GP*TP*AP*CP*G)-3', FE (II) ION, N-[(1E)-PYRIDIN-2-YLMETHYLENE]-N-[4-(4-{[(1E)-PYRIDIN-2-YLMETHYLENE]AMINO}BENZYL)PHENYL]AMINE | Authors: | Oleksi, A, Blanco, A.G, Boer, R, Uson, I, Aymami, J, Coll, M. | Deposit date: | 2005-10-27 | Release date: | 2006-03-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular Recognition of a Three-Way DNA Junction by a Metallosupramolecular Helicate ANGEW.CHEM.INT.ED.ENGL., 45, 2006
|
|
2EYM
| |
2F07
| |
2EWG
| T. brucei Farnesyl Diphosphate Synthase Complexed with Minodronate | Descriptor: | (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), MAGNESIUM ION, S-1,2-PROPANEDIOL, ... | Authors: | Cao, R, Mao, J, Gao, Y, Robinson, H, Odeh, S, Goddard, A, Oldfield, E. | Deposit date: | 2005-11-03 | Release date: | 2006-10-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes. J.Am.Chem.Soc., 128, 2006
|
|
2F0F
| |
2F0K
| |
2F0Q
| |