6TZK
 
 | | Bacterial cellulose synthase outermembrane channel BcsC with terminal TPR repeat | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... | | 著者 | Acheson, J.F, Derewenda, Z, Zimmer, J. | | 登録日 | 2019-08-12 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-02-15 | | 実験手法 | X-RAY DIFFRACTION (1.852 Å) | | 主引用文献 | Architecture of the Cellulose Synthase Outer Membrane Channel and Its Association with the Periplasmic TPR Domain.
Structure, 27, 2019
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4JPO
 | | 5A resolution structure of Proteasome Assembly Chaperone Hsm3 in complex with a C-terminal fragment of Rpt1 | | 分子名称: | 26S protease regulatory subunit 7 homolog, DNA mismatch repair protein HSM3 | | 著者 | Lovell, S, Battaile, K.P, Singh, R, Roelofs, J. | | 登録日 | 2013-03-19 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (5 Å) | | 主引用文献 | Reconfiguration of the proteasome during chaperone-mediated assembly.
Nature, 497, 2013
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3MA9
 | | Crystal structure of gp41 derived protein complexed with fab 8066 | | 分子名称: | Fab8066 FAB ANTIBODY FRAGMENT, Heavy Chain, Light Chain, ... | | 著者 | Li, M, Gustchina, E, Louis, J, Gustchina, A, Wlodawer, A, Clore, M. | | 登録日 | 2010-03-23 | | 公開日 | 2010-12-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41.
Plos Pathog., 6, 2010
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6UIX
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6U49
 | | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | | 分子名称: | Alpha-hemolysin, SULFATE ION, fos-choline-14 | | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | | 登録日 | 2019-08-23 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
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3MCZ
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2E26
 | | Crystal structure of two repeat fragment of reelin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Yasui, N, Nogi, T, Kitao, T, Takagi, J. | | 登録日 | 2006-11-08 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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6U5J
 | | CryoEM Structure of Pyocin R2 - postcontracted - collar | | 分子名称: | Collar PA0615, Sheath PA0622 | | 著者 | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | | 登録日 | 2019-08-27 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
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6ULW
 | | Adenylation, ketoreductase, and pseudo Asub multidomain structure of a keto acid-selecting NRPS module | | 分子名称: | Amino acid adenylation domain-containing protein, CALCIUM ION, MAGNESIUM ION | | 著者 | Alonzo, D.A, Wang, J, Chiche-Lapierre, C, Schmeing, T.M. | | 登録日 | 2019-10-08 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis.
Nat.Chem.Biol., 16, 2020
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6HS4
 | | Crystal structure of Ebolavirus glycoprotein in complex with inhibitor 118 | | 分子名称: | 1-[2-[3-oxidanyl-4-(4-phenyl-1~{H}-pyrazol-5-yl)phenoxy]ethyl]piperidine-4-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | | 著者 | Ren, J, Zhao, Y, Stuart, D.I. | | 登録日 | 2018-09-28 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library.
J.Med.Chem., 62, 2019
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1CG7
 | | HMG PROTEIN NHP6A FROM SACCHAROMYCES CEREVISIAE | | 分子名称: | PROTEIN (NON HISTONE PROTEIN 6 A) | | 著者 | Allain, F.H.T, Yen, Y.M, Masse, J.E, Schultze, P, Dieckmann, T, Johnson, R.C, Feigon, J. | | 登録日 | 1999-03-27 | | 公開日 | 1999-10-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding.
EMBO J., 18, 1999
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6U7V
 | | xRRM structure of spPof8 | | 分子名称: | NITRATE ION, Protein pof8 | | 著者 | Kim, J.-K, Hu, X, Yu, C, Jun, H.-I, Liu, J, Sankaran, B, Huang, L, Qiao, F. | | 登録日 | 2019-09-03 | | 公開日 | 2020-09-09 | | 最終更新日 | 2021-03-24 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Quality-Control Mechanism for Telomerase RNA Folding in the Cell.
Cell Rep, 33, 2020
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6U94
 | | Structure of RND efflux system, outer membrane lipoprotein, NodT family from Burkholderia mallei ATCC 23344 | | 分子名称: | GLYCEROL, RND efflux system, outer membrane lipoprotein, ... | | 著者 | Horanyi, P.S, Fox III, D, Abendroth, J, Lorimer, D, Edwards, T, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2019-09-06 | | 公開日 | 2019-10-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of RND efflux system, outer membrane lipoprotein, NodT family from Burkholderia mallei ATCC 23344
To Be Published
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6HXZ
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6U9L
 | | Imidazole-triggered RAS-specific subtilisin SUBT_BACAM | | 分子名称: | GLYCEROL, POTASSIUM ION, SUBTILISIN BPN', ... | | 著者 | Toth, E.A, Bryan, P.N, Orban, J. | | 登録日 | 2019-09-09 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
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6UBH
 | | Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide | | 分子名称: | Erbin, SODIUM ION, peptide | | 著者 | Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. | | 登録日 | 2019-09-11 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain.
J.Mol.Biol., 433, 2021
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1CQ6
 | | ASPARTATE AMINOTRANSFERASE COMPLEX WITH C4-PYRIDOXAL-5P-PHOSPHATE | | 分子名称: | 2-[O-PHOSPHONOPYRIDOXYL]-AMINO- BUTYRIC ACID, ASPARTATE AMINOTRANSFERASE | | 著者 | Ishijima, J, Nakai, T, Kawaguchi, S, Hirotsu, K, Kuramitsu, S. | | 登録日 | 1999-08-06 | | 公開日 | 2000-12-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Free energy requirement for domain movement of an enzyme
J.Biol.Chem., 275, 2000
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6GJU
 | | human NBD1 of CFTR in complex with nanobodies T2a and T4 | | 分子名称: | Cystic fibrosis transmembrane conductance regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. | | 登録日 | 2018-05-17 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
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1R0Q
 | | Characterization of the conversion of the malformed, recombinant cytochrome rc552 to a 2-formyl-4-vinyl (Spirographis) heme | | 分子名称: | 2-FORMYL-PROTOPORPHRYN IX, Cytochrome c-552 | | 著者 | Fee, J.A, Todaro, T.R, Luna, E, Sanders, D, Hunsicker-Wang, L.M, Patel, K.M, Bren, K.L, Gomez-Moran, E, Hill, M.G, Ai, J, Loehr, T.M, Oertling, W.A, Williams, P.A, Stout, C.D, McRee, D, Pastuszyn, A. | | 登録日 | 2003-09-22 | | 公開日 | 2004-09-28 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme.
Biochemistry, 43, 2004
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1QSQ
 | | CAVITY CREATING MUTATION | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME | | 著者 | Gassner, N.C, Baase, W.A, Lindstrom, J, Matthews, B.W. | | 登録日 | 1999-06-22 | | 公開日 | 1999-06-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.
Biochemistry, 38, 1999
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1QVY
 | | Crystal structure of RhoGDI K(199,200)R double mutant | | 分子名称: | Rho GDP-dissociation inhibitor 1, SULFATE ION | | 著者 | Czepas, J, Devedjiev, Y, Krowarsh, D, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2003-08-29 | | 公開日 | 2004-02-10 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The impact of Lys-->Arg surface mutations on the crystallization of the globular domain of RhoGDI.
Acta Crystallogr.,Sect.D, 60, 2004
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6UIG
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6GOS
 | | E. coli Microcin synthetase McbBCD complex with pro-MccB17 bound | | 分子名称: | 1,2-ETHANEDIOL, Bacteriocin microcin B17, CHLORIDE ION, ... | | 著者 | Ghilarov, D, Stevenson, C.E.M, Travin, D.Y, Piskunova, J, Serebryakova, M, Maxwell, A, Lawson, D.M, Severinov, K. | | 登録日 | 2018-06-04 | | 公開日 | 2019-01-30 | | 最終更新日 | 2019-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
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6SR6
 | | Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein, ... | | 著者 | Valentin Gese, G, Lapouge, K, Kopp, J, Sinning, I. | | 登録日 | 2019-09-05 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb.
Nat Commun, 11, 2020
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6GQD
 | | Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L | | 分子名称: | 1,2-ETHANEDIOL, 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, Galactose-1-phosphate uridylyltransferase, ... | | 著者 | Fairhead, M, Strain-Damerell, C, Kopec, J, Bezerra, G.A, Zhang, M, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W, Structural Genomics Consortium (SGC) | | 登録日 | 2018-06-07 | | 公開日 | 2018-07-18 | | 実験手法 | X-RAY DIFFRACTION (1.523 Å) | | 主引用文献 | Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L
To Be Published
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