5HHO
 
 | | Crystal Structure of the JM22 TCR in complex with HLA-A*0201 in complex with M1-G4E | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | | 著者 | Gras, S, Josephs, T.M, Rossjohn, J. | | 登録日 | 2016-01-11 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1HNH
 | | CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III + DEGRADED FORM OF ACETYL-COA | | 分子名称: | BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III, COENZYME A | | 著者 | Qiu, X, Janson, C.A, Smith, W.W, Head, M, Lonsdale, J, Konstantinidis, A.K. | | 登録日 | 2000-12-07 | | 公開日 | 2000-12-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Refined structures of beta-ketoacyl-acyl carrier protein synthase III.
J.Mol.Biol., 307, 2001
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5NRV
 | | Human DNMT3B PWWP domain in complex with 6-dipropylamino-1-hexanol | | 分子名称: | 6-dipropylamino-1-hexanol, DNA (cytosine-5)-methyltransferase 3B, SULFATE ION | | 著者 | Rondelet, G, Wouters, J. | | 登録日 | 2017-04-25 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.075 Å) | | 主引用文献 | Targeting PWWP domain of DNA methyltransferase 3B for epigenetic cancer therapy: Identification and structural characterization of new potential protein-protein interaction inhibitors
To be published
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6FCI
 | | Crystal Structure of Human APRT wild type in complex with Adenine, PRPP and Mg2+ | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ADENINE, Adenine phosphoribosyltransferase, ... | | 著者 | Nioche, P, Huyet, J, Ozeir, M. | | 登録日 | 2017-12-20 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structural Insights into the Forward and Reverse Enzymatic Reactions in Human Adenine Phosphoribosyltransferase.
Cell Chem Biol, 25, 2018
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5HPN
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6FB7
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5NBB
 | | Structure of the C-terminal domain of the Escherichia Coli ProQ RNA binding protein | | 分子名称: | RNA chaperone ProQ | | 著者 | Gonzales, G, Hardwick, S, Maslen, S, Skehel, M, Holmqvist, E, Vogel, J, Bateman, A, Luisi, B, Broadhurst, R. | | 登録日 | 2017-03-01 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Escherichia coli ProQ RNA-binding protein.
RNA, 23, 2017
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5HQ3
 | | Stable, high-expression variant of human acetylcholinesterase | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetylcholinesterase, O-ETHYLMETHYLPHOSPHONIC ACID ESTER GROUP | | 著者 | Goldenzweig, A, Goldsmith, M, Hill, S.E, Gertman, O, Laurino, P, Ashani, Y, Dym, O, Albeck, S, Unger, T, Prilusky, J, Lieberman, R.L, Aharoni, A, Silman, I, Sussman, J.L, Tawfik, D.S, Fleishman, S.J. | | 登録日 | 2016-01-21 | | 公開日 | 2016-07-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.
Mol.Cell, 63, 2016
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1HU9
 | | LIPOXYGENASE-3 (SOYBEAN) COMPLEX WITH 4-HYDROPEROXY-2-METHOXY-PHENOL | | 分子名称: | 4-HYDROPEROXY-2-METHOXY-PHENOL, FE (III) ION, LIPOXYGENASE-3 | | 著者 | Zhou, K, Skrzypczak-Jankun, E, McCabe, N.P, Selman, S.H, Jankun, J. | | 登録日 | 2001-01-04 | | 公開日 | 2003-06-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of curcumin in complex with lipoxygenase and its significance in
cancer.
INT.J.MOL.MED., 12, 2003
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5NG6
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5N2O
 | | Structure Of P63 SAM Domain L514F Mutant Causative Of AEC Syndrome | | 分子名称: | Tumor protein 63 | | 著者 | Rinnenthal, J, Wuerz, J.M, Osterburg, C, Guentert, P, Doetsch, V. | | 登録日 | 2017-02-08 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1GMP
 | | COMPLEX OF RIBONUCLEASE FROM STREPTOMYCES AUREOFACIENS WITH 2'-GMP AT 1.7 ANGSTROMS RESOLUTION | | 分子名称: | GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE SA, SULFATE ION | | 著者 | Sevcik, J, Hill, C, Dauter, Z, Wilson, K. | | 登録日 | 1992-10-01 | | 公開日 | 1993-10-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Complex of ribonuclease from Streptomyces aureofaciens with 2'-GMP at 1.7 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
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3S8P
 | | Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 In Complex With S-Adenosyl-L-Methionine | | 分子名称: | Histone-lysine N-methyltransferase SUV420H1, S-ADENOSYLMETHIONINE, ZINC ION | | 著者 | Lam, R, Zeng, H, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2011-05-30 | | 公開日 | 2011-07-06 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2.
Febs Lett., 587, 2013
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5NB9
 | | Structure of the N-terminal domain of the Escherichia Coli ProQ RNA binding protein | | 分子名称: | RNA chaperone ProQ | | 著者 | Gonzales, G, Hardwick, S, Maslen, S, Skehel, M, Holmqvist, E, Vogel, J, Bateman, A, Luisi, B, Broadhurst, R. | | 登録日 | 2017-03-01 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Escherichia coli ProQ RNA-binding protein.
RNA, 23, 2017
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6FEQ
 | | Structure of inhibitor-bound ABCG2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | | 著者 | Jackson, S.M, Manolaridis, I, Kowal, J, Zechner, M, Altmann, K.H, Locher, K.P. | | 登録日 | 2018-01-03 | | 公開日 | 2018-04-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.
Nat. Struct. Mol. Biol., 25, 2018
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5NDA
 | | NMR Structural Characterisation of Pharmaceutically Relevant Proteins Obtained Through a Novel Recombinant Production: The Case of The Pulmonary Surfactant Polypeptide C Analogue rSP-C33Leu. | | 分子名称: | rSP-C33Leu -RECOMBINANT PULMONARY SURFACTANT-ASSOCIATED POLYPEPTIDE C ANALOGUE- | | 著者 | Venturi, L, Pioselli, B, Johansson, J, Rising, A, Kronqvist, N, Nordling, K. | | 登録日 | 2017-03-08 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Efficient protein production inspired by how spiders make silk.
Nat Commun, 8, 2017
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5HUN
 | | The crystal structure of neuraminidase from A/gyrfalcon/Washington/41088-6/2014 influenza virus | | 分子名称: | CALCIUM ION, Neuraminidase | | 著者 | Yang, H, Carney, P.J, Guo, Z, Chang, J.C, Stevens, J. | | 登録日 | 2016-01-27 | | 公開日 | 2016-04-13 | | 最終更新日 | 2016-06-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular Characterizations of Surface Proteins Hemagglutinin and Neuraminidase from Recent H5Nx Avian Influenza Viruses.
J.Virol., 90, 2016
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1GMR
 | | COMPLEX OF RIBONUCLEASE FROM STREPTOMYCES AUREOFACIENS WITH 2'-GMP AT 1.7 ANGSTROMS RESOLUTION | | 分子名称: | GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE SA, SULFATE ION | | 著者 | Sevcik, J, Hill, C, Dauter, Z, Wilson, K. | | 登録日 | 1992-10-01 | | 公開日 | 1993-10-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Complex of ribonuclease from Streptomyces aureofaciens with 2'-GMP at 1.7 A resolution.
Acta Crystallogr.,Sect.D, 49, 1993
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5HY4
 | | Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes | | 分子名称: | Ring-opening amidohydrolase | | 著者 | Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C. | | 登録日 | 2016-02-01 | | 公開日 | 2017-02-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.
Appl. Environ. Microbiol., 83, 2017
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6FHL
 | | Cryo-EM structure of F-actin in complex with ADP-Pi | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Merino, F, Pospich, S, Funk, J, Wagner, T, Kuellmer, F, Arndt, H.-D, Bieling, P, Raunser, S. | | 登録日 | 2018-01-15 | | 公開日 | 2018-06-13 | | 最終更新日 | 2018-08-29 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
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5HZ0
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5NTH
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1GN7
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5NTP
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5NTQ
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