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PDB: 190 件

6IGB
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the structure of Pseudomonas aeruginosa Periplasmic gluconolactonase, PpgL
分子名称: ACETATE ION, Periplasmic gluconolactonase, PpgL, ...
著者Song, Y.J, Shen, Y.L, Wang, K.L, Li, T, Zhu, Y.B, Li, C.C, He, L.H, Zhao, N.L, Zhao, C, Yang, J, Huang, Q, Mu, X.Y.
登録日2018-09-25
公開日2018-11-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Structural and Functional Insights into PpgL, a Metal-Independent beta-Propeller Gluconolactonase That Contributes toPseudomonas aeruginosaVirulence.
Infect.Immun., 87, 2019
4GV3
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Structures of Lassa and Tacaribe viral nucleoproteins with or without 5 triphosphate dsRNA substrate reveal a unique 3 -5 exoribonuclease mechanism to suppress type I interferon production
分子名称: MANGANESE (II) ION, Nucleoprotein, RNA (5'-R(*(GTP)P*GP*GP*C)-3'), ...
著者Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
登録日2012-08-30
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4G9Z
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Lassa nucleoprotein with dsRNA reveals novel mechanism for immune suppression
分子名称: Nucleoprotein, RNA (5'-R(P*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*C)-3'), ...
著者Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C, Scottish Structural Proteomics Facility (SSPF)
登録日2012-07-24
公開日2013-04-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
6JAU
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The complex structure of Pseudomonas aeruginosa MucA/MucB.
分子名称: CALCIUM ION, GLYCEROL, HEXAETHYLENE GLYCOL, ...
著者Li, T, He, L.H, Li, C.C, Liu, L, Peng, C.T, Shen, Y.L, Qin, X.F, Xiao, Q.J, Zhu, Y.B, Song, Y.J, Zhao, N.l, Zhao, C, Yang, J, Mu, X.Y, Huang, Q, Bao, R.
登録日2019-01-25
公開日2020-01-29
最終更新日2020-08-19
実験手法X-RAY DIFFRACTION (1.905 Å)
主引用文献Molecular basis of the lipid-induced MucA-MucB dissociation in Pseudomonas aeruginosa.
Commun Biol, 3, 2020
5Y28
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Crystal structure of H. pylori HtrA with PDZ2 deletion
分子名称: 1,2-ETHANEDIOL, Periplasmic serine endoprotease DegP-like, UNK-UNK-UNK-UNK
著者Zhang, Z, Huang, Q, Tao, X.
登録日2017-07-24
公開日2018-08-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.08606815 Å)
主引用文献The unique trimeric assembly of the virulence factor HtrA fromHelicobacter pylorioccurs via N-terminal domain swapping.
J.Biol.Chem., 294, 2019
5Y2D
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Crystal structure of H. pylori HtrA
分子名称: Periplasmic serine endoprotease DegP-like, UNK-UNK-K-UNK-UNK-UNK-UNK-UNK-UNK-UNK, UNK-UNK-UNK, ...
著者Zhang, Z, Huang, Q, Tao, X.
登録日2017-07-25
公開日2018-08-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.70009851 Å)
主引用文献The unique trimeric assembly of the virulence factor HtrA fromHelicobacter pylorioccurs via N-terminal domain swapping.
J.Biol.Chem., 294, 2019
2H40
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Crystal structure of the catalytic domain of unliganded PDE5
分子名称: MAGNESIUM ION, ZINC ION, cGMP-specific 3',5'-cyclic phosphodiesterase
著者Wang, H, Liu, Y, Huai, Q, Cai, J, Zoraghi, R, Francis, S.H, Corbin, J.D, Robinson, H, Xin, Z, Lin, G, Ke, H.
登録日2006-05-23
公開日2006-06-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Multiple Conformations of Phosphodiesterase-5: Implications for enzyme function and drug development
J.Biol.Chem., 281, 2006
6JYK
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Crystal Structure of C. crescentus free GapR
分子名称: UPF0335 protein CCNA_03428
著者Xia, B, Huang, Q.
登録日2019-04-26
公開日2020-08-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献GapR binds DNA through dynamic opening of its tetrameric interface.
Nucleic Acids Res., 48, 2020
6K2J
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Crystal Structure of the DNA Complex of C. crescentus GapR
分子名称: 10A DNA_front, 10A DNA_reverse, UPF0335 protein CCNA_03428
著者Xia, B, Huang, Q.
登録日2019-05-14
公開日2020-08-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献GapR binds DNA through dynamic opening of its tetrameric interface.
Nucleic Acids Res., 48, 2020
6K5X
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Crystal Structure of the DNA-Binding Domain of GapR
分子名称: SULFATE ION, UPF0335 protein CCNA_03428
著者Xia, B, Huang, Q.
登録日2019-05-31
公開日2020-06-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.086 Å)
主引用文献Crystal Structure of the DNA-Binding Domain of GapR
To Be Published
7VW3
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Cryo-EM structure of SaCas9-sgRNA-DNA ternary complex
分子名称: CRISPR-associated endonuclease Cas9, MAGNESIUM ION, Non-target DNA strand, ...
著者Du, W.H, Qian, J.Q, Huang, Q.
登録日2021-11-09
公開日2023-03-15
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Full-Length Model of SaCas9-sgRNA-DNA Complex in Cleavage State.
Int J Mol Sci, 24, 2023
7EBQ
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The structural analysis of A.Muciniphila sulfatase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Sulfatase
著者Bao, R, Li, C.C, Tang, X.Y, Zhu, Y.B, Song, Y.J, Zhao, N.L, Huang, Q, Mou, X.Y, Luo, G.H, Liu, T.G.
登録日2021-03-10
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural analysis of the sulfatase AmAS from Akkermansia muciniphila.
Acta Crystallogr D Struct Biol, 77, 2021
7EBP
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The structural analysis of A.Muciniphila sulfatase
分子名称: CALCIUM ION, GLYCEROL, Sulfatase
著者Bao, R, Li, C.C, Tang, X.Y, Zhu, Y.B, Song, Y.J, Zhao, N.L, Huang, Q, Mou, X.Y, Luo, G.H, Liu, T.G.
登録日2021-03-10
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.80000055 Å)
主引用文献Structural analysis of the sulfatase AmAS from Akkermansia muciniphila.
Acta Crystallogr D Struct Biol, 77, 2021
7EZT
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The structure and functional mechanism of nucleotide regulated acetylhexosaminidase Am2136 from Akkermansia muciniphila
分子名称: Beta-N-acetylhexosaminidase, MAGNESIUM ION
著者Bao, R, Li, C.C, Tang, X.Y, Zhu, Y.B, Song, Y.J, Zhao, N.L, Huang, Q, Mou, X.Y, Luo, G.H, Liu, T.G.
登録日2021-06-02
公開日2022-11-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Nucleotide binding as an allosteric regulatory mechanism for Akkermansia muciniphila beta- N -acetylhexosaminidase Am2136.
Gut Microbes, 14, 2022
2OAE
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Crystal structure of rat dipeptidyl peptidase (DPPIV) with thiazole-based peptide mimetic #31
分子名称: Dipeptidyl peptidase 4, N-{[(3S,5S)-5-(1,3-THIAZOLIDIN-3-YLCARBONYL)PYRROLIDIN-3-YL]METHYL}-1,3-THIAZOLE-4-CARBOXAMIDE, SULFATE ION
著者Longenecker, K.L, Shuai, Q, Patel, J, Wiedeman, P.
登録日2006-12-15
公開日2007-02-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit.
Bioorg.Med.Chem.Lett., 17, 2007

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