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PDB: 238 results

8TLJ
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BU of 8tlj by Molmil
CDCA7 (Mouse) Binds Non-B-form 32-mer DNA oligo Containing a 5mC
Descriptor: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (32-MER), ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
8TLK
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BU of 8tlk by Molmil
CDCA7 (Human) Binds Non-B-form 32-mer DNA oligo Containing a 5mC
Descriptor: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (32-MER), ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
8TLE
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BU of 8tle by Molmil
CDCA7 (Mouse) Binds Non-B-form 36-mer DNA oligo (sg C2-Form 1)
Descriptor: Cell division cycle-associated protein 7, MAGNESIUM ION, ZINC ION, ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
8TLF
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BU of 8tlf by Molmil
CDCA7 (Mouse) Binds Non-B-form DNA oligo 36-mer (sg C2-Form 2)
Descriptor: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, GLYCEROL, ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
8TLH
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BU of 8tlh by Molmil
CDCA7 (Mouse) Binds Non-B-form 32-mer DNA oligo
Descriptor: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (32-MER), ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
8TLG
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BU of 8tlg by Molmil
CDCA7 (Mouse) Binds Non-B-form 34-mer DNA oligo
Descriptor: 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (34-MER), ...
Authors:Horton, J.R, Ren, R, Cheng, X.
Deposit date:2023-07-26
Release date:2024-08-21
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Biorxiv, 2023
2H11
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BU of 2h11 by Molmil
Amino-terminal Truncated Thiopurine S-Methyltransferase Complexed with S-Adenosyl-L-Homocysteine
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-ADENOSYL-L-HOMOCYSTEINE, THIOCYANATE ION, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2006-05-15
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural basis of allele variation of human thiopurine-S-methyltransferase.
Proteins, 67, 2007
2G1P
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BU of 2g1p by Molmil
Structure of E. coli DNA adenine methyltransferase (DAM)
Descriptor: 5'-D(*TP*CP*TP*AP*GP*AP*TP*CP*TP*AP*GP*A)-3', DNA adenine methylase, GLYCEROL, ...
Authors:Horton, J.R, Liebert, K, Bekes, M, Jeltsch, A, Cheng, X.
Deposit date:2006-02-14
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase.
J.Mol.Biol., 358, 2006
6MBJ
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BU of 6mbj by Molmil
SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, P21 Crystal Form
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Actin Peptide, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2018-08-30
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:SETD3 is an actin histidine methyltransferase that prevents primary dystocia.
Nature, 565, 2019
6MG1
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BU of 6mg1 by Molmil
C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence-C2 Crystal Form
Descriptor: 1,2-ETHANEDIOL, 16-bp methylated oligonucleotide, CCAAT/enhancer-binding protein beta, ...
Authors:Horton, J.R, Cheng, X, Yang, J.
Deposit date:2018-09-12
Release date:2018-12-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for effects of CpA modifications on C/EBP beta binding of DNA.
Nucleic Acids Res., 47, 2019
6MBK
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SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, First P212121 Crystal Form
Descriptor: 1,2-ETHANEDIOL, Actin peptide, GLYCEROL, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2018-08-30
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:SETD3 is an actin histidine methyltransferase that prevents primary dystocia.
Nature, 565, 2019
6MBO
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BU of 6mbo by Molmil
GLP Methyltransferase with Inhibitor EML741-P212121 Crystal Form
Descriptor: 1,2-ETHANEDIOL, 2-cyclohexyl-7-methoxy-N-[1-(propan-2-yl)piperidin-4-yl]-8-[3-(pyrrolidin-1-yl)propoxy]-3H-1,4-benzodiazepin-5-amine, Histone-lysine N-methyltransferase EHMT1, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2018-08-30
Release date:2019-02-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.591 Å)
Cite:Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure.
J. Med. Chem., 62, 2019
6MG3
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BU of 6mg3 by Molmil
V285A Mutant of the C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence
Descriptor: 1,2-ETHANEDIOL, 16-bp methylated oligonucleotide, CCAAT/enhancer-binding protein beta
Authors:Horton, J.R, Cheng, X, Yang, J.
Deposit date:2018-09-12
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for effects of CpA modifications on C/EBP beta binding of DNA.
Nucleic Acids Res., 47, 2019
6MBL
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BU of 6mbl by Molmil
SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, Second P212121 Crystal Form
Descriptor: 1,2-ETHANEDIOL, Actin Peptide, Histone-lysine N-methyltransferase setd3, ...
Authors:Horton, J.R, Dai, S, Cheng, X.
Deposit date:2018-08-30
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:SETD3 is an actin histidine methyltransferase that prevents primary dystocia.
Nature, 565, 2019
6MG2
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BU of 6mg2 by Molmil
C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence-C2221 Crystal Form
Descriptor: 1,2-ETHANEDIOL, 16-bp methylated oligonucleotide, CCAAT/enhancer-binding protein beta
Authors:Horton, J.R, Cheng, X, Yang, J.
Deposit date:2018-09-12
Release date:2018-12-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.928 Å)
Cite:Structural basis for effects of CpA modifications on C/EBP beta binding of DNA.
Nucleic Acids Res., 47, 2019
6ML6
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BU of 6ml6 by Molmil
ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 4 with a CpA 5mC Modification)
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*GP*(5CM)P*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*CP*GP*AP*AP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*TP*TP*CP*GP*TP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ...
Authors:Horton, J.R, Cheng, X, Ren, R.
Deposit date:2018-09-26
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural basis of specific DNA binding by the transcription factor ZBTB24.
Nucleic Acids Res., 47, 2019
6ML5
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BU of 6ml5 by Molmil
ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 4)
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*CP*GP*AP*AP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*TP*TP*CP*GP*TP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ...
Authors:Horton, J.R, Cheng, X, Ren, R.
Deposit date:2018-09-26
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis of specific DNA binding by the transcription factor ZBTB24.
Nucleic Acids Res., 47, 2019
6ML4
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BU of 6ml4 by Molmil
BTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 3)
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*CP*GP*AP*AP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*GP*TP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ...
Authors:Horton, J.R, Cheng, X, Ren, R.
Deposit date:2018-09-26
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:Structural basis of specific DNA binding by the transcription factor ZBTB24.
Nucleic Acids Res., 47, 2019
6ML2
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BU of 6ml2 by Molmil
ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 1)
Descriptor: DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*CP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ZINC ION, ...
Authors:Horton, J.R, Cheng, X, Ren, R.
Deposit date:2018-09-26
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.874 Å)
Cite:Structural basis of specific DNA binding by the transcription factor ZBTB24.
Nucleic Acids Res., 47, 2019
6ML7
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BU of 6ml7 by Molmil
ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 4 with a CpG 5mC Modification)
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*(5CM)P*GP*AP*AP*TP*T)-3'), ...
Authors:Horton, J.R, Cheng, X, Ren, R.
Deposit date:2018-09-26
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis of specific DNA binding by the transcription factor ZBTB24.
Nucleic Acids Res., 47, 2019
6ML3
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BU of 6ml3 by Molmil
ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 2)
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*CP*TP*TP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ...
Authors:Horton, J.R, Cheng, X, Ren, R.
Deposit date:2018-09-26
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.683 Å)
Cite:Structural basis of specific DNA binding by the transcription factor ZBTB24.
Nucleic Acids Res., 47, 2019
1SKM
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BU of 1skm by Molmil
HhaI methyltransferase in complex with DNA containing an abasic south carbocyclic sugar at its target site
Descriptor: 5'-D(*T*GP*TP*CP*AP*GP*(HCX)P*GP*CP*AP*TP*GP*G)-3', 5'-D(*TP*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', Modification methylase HhaI, ...
Authors:Horton, J.R, Ratner, G, Banavali, N, Huang, N, Marquez, V.E, MacKerell, A.D, Cheng, X.
Deposit date:2004-03-05
Release date:2004-08-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferase
Nucleic Acids Res., 32, 2004
6OD5
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BU of 6od5 by Molmil
Human TCF4 C-terminal bHLH domain in Complex with 12-bp Oligonucleotide Containing E-box Sequence with 5-carboxylcytosines
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*AP*(1CC)P*GP*CP*AP*CP*GP*TP*GP*(1CC)P*G)-3'), ...
Authors:Horton, J.R, Cheng, X, Yang, J.
Deposit date:2019-03-25
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.
Nucleic Acids Res., 47, 2019
7M10
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BU of 7m10 by Molmil
PHF2 PHD Domain Complexed with Peptide From N-terminus of VRK1
Descriptor: FORMIC ACID, Lysine-specific demethylase PHF2, Serine/threonine-protein kinase VRK1 N-terminus peptide, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2021-03-11
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions.
Biochem.J., 478, 2021
6B0Q
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BU of 6b0q by Molmil
Zinc finger Domain of WT1(-KTS form) with 13+1mer Oligonucleotide with 3' Triplet TGT
Descriptor: DNA (5'-D(P*AP*AP*CP*AP*CP*TP*CP*CP*CP*AP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*TP*GP*GP*GP*AP*GP*TP*GP*TP*T)-3'), SULFATE ION, ...
Authors:Horton, J.R, Cheng, X.
Deposit date:2017-09-14
Release date:2018-01-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.794 Å)
Cite:Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites.
Nucleic Acids Res., 46, 2018

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PDB entries from 2024-08-28

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