5E21
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![BU of 5e21 by Molmil](/molmil-images/mine/5e21) | PDZ2 of LNX2 at 277K,single conformer model | 分子名称: | Ligand of Numb protein X 2 | 著者 | Hekstra, D.R, White, K.I, Socolich, M.A, Ranganathan, R. | 登録日 | 2015-09-30 | 公開日 | 2016-12-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.011 Å) | 主引用文献 | Electric-field-stimulated protein mechanics. Nature, 540, 2016
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5E11
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![BU of 5e11 by Molmil](/molmil-images/mine/5e11) | Second PDZ domain of Ligand of Numb protein X 2 by Laue crystallography (no electric field) | 分子名称: | Ligand of Numb protein X 2 | 著者 | Hekstra, D.R, White, K.I, Socolich, M.A, Henning, R.W, Srajer, V, Ranganathan, R. | 登録日 | 2015-09-29 | 公開日 | 2016-12-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Electric-field-stimulated protein mechanics. Nature, 540, 2016
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5E22
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![BU of 5e22 by Molmil](/molmil-images/mine/5e22) | The second PDZ domain of Ligand of Numb protein X 2 in the presence of an electric field of ~1 MV/cm along the crystallographic x axis, with eightfold extrapolation of structure factor differences. | 分子名称: | GLYCEROL, Ligand of Numb protein X 2 | 著者 | Hekstra, D.R, White, K.I, Socolich, M.A, Henning, R.W, Srajer, V, Ranganathan, R. | 登録日 | 2015-09-30 | 公開日 | 2016-12-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.797 Å) | 主引用文献 | Electric-field-stimulated protein mechanics. Nature, 540, 2016
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5E1Y
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![BU of 5e1y by Molmil](/molmil-images/mine/5e1y) | PDZ2 of LNX2 at 277K, model with alternate conformations | 分子名称: | Ligand of Numb protein X 2 | 著者 | Hekstra, D.R, White, K.I, Socolich, M.A, Ranganathan, R. | 登録日 | 2015-09-30 | 公開日 | 2016-12-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.011 Å) | 主引用文献 | Electric-field-stimulated protein mechanics. Nature, 540, 2016
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9B7C
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![BU of 9b7c by Molmil](/molmil-images/mine/9b7c) | |
8G4Z
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![BU of 8g4z by Molmil](/molmil-images/mine/8g4z) | E. coli DHFR complex with NADP+ and folate: EF-X off model by Laue diffraction (no electric field) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Klureza, M.A, Hekstra, D.R. | 登録日 | 2023-02-10 | 公開日 | 2024-01-03 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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8G50
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![BU of 8g50 by Molmil](/molmil-images/mine/8g50) | E. coli DHFR complex with NADP+ and folate: EF-X excited state model by Laue diffraction (electric field along b axis; 8-fold extrapolation of structure factor differences) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Klureza, M.A, Hekstra, D.R. | 登録日 | 2023-02-10 | 公開日 | 2024-01-03 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7RIN
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![BU of 7rin by Molmil](/molmil-images/mine/7rin) | |
5SST
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![BU of 5sst by Molmil](/molmil-images/mine/5sst) | DHFR:NADP+:FOL complex at 270 K (crystal 2) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-07-03 | 公開日 | 2023-08-23 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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5SSS
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![BU of 5sss by Molmil](/molmil-images/mine/5sss) | DHFR:NADP+:FOL complex at 270 K (crystal 1) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-07-03 | 公開日 | 2023-08-23 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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5SSU
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![BU of 5ssu by Molmil](/molmil-images/mine/5ssu) | DHFR:NADP+:FOL complex at 270 K (crystal 3) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-07-03 | 公開日 | 2023-08-23 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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5SSW
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![BU of 5ssw by Molmil](/molmil-images/mine/5ssw) | DHFR:NADP+:FOL complex at 270 K (multi-crystal) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-07-03 | 公開日 | 2023-08-23 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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5SSV
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![BU of 5ssv by Molmil](/molmil-images/mine/5ssv) | DHFR:NADP+:FOL complex at 270 K (crystal 4) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-07-03 | 公開日 | 2023-08-23 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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8DAI
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![BU of 8dai by Molmil](/molmil-images/mine/8dai) | E. coli DHFR complex with NADP+ and 10-methylfolate | 分子名称: | Dihydrofolate reductase, MANGANESE (II) ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Greisman, J.B, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-06-13 | 公開日 | 2023-06-21 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FQ2
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![BU of 7fq2 by Molmil](/molmil-images/mine/7fq2) | DHFR:NADP+:FOL complex at 300 K (multi-crystal) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-10 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FPM
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![BU of 7fpm by Molmil](/molmil-images/mine/7fpm) | DHFR:NADP+:FOL complex at 280 K (crystal 2) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-09 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FQ5
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![BU of 7fq5 by Molmil](/molmil-images/mine/7fq5) | DHFR:NADP+:FOL complex at 310 K (crystal 3) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FPO
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![BU of 7fpo by Molmil](/molmil-images/mine/7fpo) | DHFR:NADP+:FOL complex at 280 K (crystal 4) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-09 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FQF
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![BU of 7fqf by Molmil](/molmil-images/mine/7fqf) | DHFR:NADP+:FOL complex (crystal 2, pass 4, 310 K) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FPS
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![BU of 7fps by Molmil](/molmil-images/mine/7fps) | DHFR:NADP+:FOL complex at 290 K (crystal 2) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-10 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FQ8
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![BU of 7fq8 by Molmil](/molmil-images/mine/7fq8) | DHFR:NADP+:FOL complex (crystal 1, pass 2, 310 K) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FPN
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![BU of 7fpn by Molmil](/molmil-images/mine/7fpn) | DHFR:NADP+:FOL complex at 280 K (crystal 3) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-09 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FQE
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![BU of 7fqe by Molmil](/molmil-images/mine/7fqe) | DHFR:NADP+:FOL complex (crystal 2, pass 3, 295 K) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FPR
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![BU of 7fpr by Molmil](/molmil-images/mine/7fpr) | DHFR:NADP+:FOL complex at 290 K (crystal 1) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-10 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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7FQG
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![BU of 7fqg by Molmil](/molmil-images/mine/7fqg) | DHFR:NADP+:FOL complex (crystal 2, pass 5, 295 K) | 分子名称: | Dihydrofolate reductase, FOLIC ACID, MANGANESE (II) ION, ... | 著者 | Greisman, J.B, Dalton, K.M, Brookner, D.E, Hekstra, D.R. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism. Proc.Natl.Acad.Sci.USA, 121, 2024
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