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PDB: 22488 件

3OZZ
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Structure of a cytochrome b5 core-swap mutant
分子名称: Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE
著者Terzyan, S, Parthasarathy, S, Zhang, X.C, Benson, D.
登録日2010-09-27
公開日2011-09-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of a cytochrome b5 core-swap mutant
To be Published
4J2W
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Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
著者Amaral, M, Levy, C, Heyes, D.J, Lafite, P, Outeiro, T.F, Giorgini, F, Leys, D, Scrutton, N.S.
登録日2013-02-05
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of kynurenine 3-monooxygenase inhibition.
Nature, 496, 2013
2J9Y
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Tryptophan Synthase Q114N mutant in complex with Compound II
分子名称: (3E)-4-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}-2-IMINOBUT-3-ENOIC ACID, SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ...
著者Blumenstein, L, Domratcheva, T, Niks, D, Ngo, H, Seidel, R, Dunn, M.F, Schlichting, I.
登録日2006-11-16
公開日2007-12-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Betaq114N and Betat110V Mutations Reveal a Critically Important Role of the Substrate Alpha-Carboxylate Site in the Reaction Specificity of Tryptophan Synthase.
Biochemistry, 46, 2007
2J9Z
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Tryptophan Synthase T110 mutant complex
分子名称: PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ...
著者Blumenstein, L, Domratcheva, T, Niks, D, Ngo, H, Seidel, R, Dunn, M.F, Schlichting, I.
登録日2006-11-16
公開日2007-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Betaq114N and Betat110V Mutations Reveal a Critically Important Role of the Substrate Alpha-Carboxylate Site in the Reaction Specificity of Tryptophan Synthase.
Biochemistry, 46, 2007
2JAG
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L1-intermediate of halorhodopsin T203V
分子名称: CHLORIDE ION, Halorhodopsin, PALMITIC ACID, ...
著者Gmelin, W, Zeth, K, Efremov, R, Heberle, J, Tittor, J, Oesterhelt, D.
登録日2006-11-28
公開日2006-12-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献The crystal structure of the L1 intermediate of halorhodopsin at 1.9 angstroms resolution.
Photochem. Photobiol., 83, 2007
2JCN
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The crystal structure of BAK1 - a mitochondrial apoptosis regulator
分子名称: BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, SULFATE ION
著者Moche, M, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Johansson, I, Karlberg, T, Kosinska, U, Kotenyova, T, Lundgren, S, Nilsson, M.E, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Upsten, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2006-12-27
公開日2007-01-04
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of Bak1 - an Apoptosis Trigger in the Mitochondrial Outer Membrane
To be Published
2JDQ
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C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5
分子名称: IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2
著者Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S.
登録日2007-01-11
公開日2007-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit
Nat.Struct.Mol.Biol., 14, 2007
3P5J
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The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease
分子名称: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
著者Bubeck, D, Graham, S.C, Jones, E.Y.
登録日2010-10-08
公開日2010-11-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease.
J.Biol.Chem., 286, 2011
3P8T
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Crystal structure of the archaeal asparagine synthetase A
分子名称: AsnS-like asparaginyl-tRNA synthetase related protein
著者Blaise, M, Kern, D.
登録日2010-10-15
公開日2011-08-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
2JAB
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A designed ankyrin repeat protein evolved to picomolar affinity to Her2
分子名称: H10-2-G3
著者Zahnd, C, Wyler, E, Schwenk, J.M, Steiner, D, Lawrence, M.C, McKern, N.M, Pecorari, F, Ward, C.W, Joos, T.O, Pluckthun, A.
登録日2006-11-27
公開日2007-05-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Designed Ankyrin Repeat Protein Evolved to Picomolar Affinity to Her2
J.Mol.Biol., 369, 2007
3P1X
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Crystal structure of DRBM 2 domain of Interleukin enhancer-binding factor 3 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4527E
分子名称: Interleukin enhancer-binding factor 3
著者Seetharaman, J, Neely, H, Wang, D, Janjua, H, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2010-09-30
公開日2010-12-29
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of DRBM 2 domain of Interleukin enhancer-binding factor 3 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4527E
To be Published
5XXB
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Large subunit of Toxoplasma gondii ribosome
分子名称: 25S RNA, 5.8S RNA, 5S RNA, ...
著者Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N.
登録日2017-07-03
公開日2017-08-30
最終更新日2017-10-18
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
2JR6
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BU of 2jr6 by Molmil
Solution structure of UPF0434 protein NMA0874. Northeast Structural Genomics Target MR32
分子名称: UPF0434 protein NMA0874
著者Ghosh, A, Singarapu, K.K, Wu, Y, Liu, G, Sukumaran, D, Chen, C.X, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2007-06-20
公開日2007-07-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of UPF0434 protein NMA0874.
To be Published
2JST
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Four-Alpha-Helix Bundle with Designed Anesthetic Binding Pockets II: Halothane Effects on Structure and Dynamics
分子名称: 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE, Four-Alpha-Helix Bundle
著者Cui, T, Bondarenko, V, Ma, D, Canlas, C, Brandon, N.R, Johansson, J.S, Tang, P, Xu, Y.
登録日2007-07-12
公開日2008-05-27
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics
Biophys.J., 94, 2008
4IWO
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Crystal structure and mechanism of activation of TBK1
分子名称: N-{3-[(5-cyclopropyl-2-{[3-(2-oxopyrrolidin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide, Serine/threonine-protein kinase TBK1
著者Panne, D, Larabi, A.
登録日2013-01-24
公開日2013-03-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Crystal structure and mechanism of activation of TANK-binding kinase 1.
Cell Rep, 3, 2013
3P8C
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Structure and Control of the Actin Regulatory WAVE Complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Abl interactor 2, CHLORIDE ION, ...
著者Chen, Z, Borek, D, Padrick, S.B, Gomez, T.S, Metlagel, Z, Ismail, A.M, Umetani, J, Billadeau, D.D, Otwinowski, Z, Rosen, M.K.
登録日2010-10-13
公開日2010-12-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure and control of the actin regulatory WAVE complex.
Nature, 468, 2010
4IYE
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Crystal structure of AdTx1 (rho-Da1a) from eastern green mamba (Dendroaspis angusticeps)
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Toxin AdTx1
著者Stura, E.A, Vera, L, Maiga, A.A, Marchetti, C, Lorphelin, A, Bellanger, L, Servant, D, Gilles, N.
登録日2013-01-28
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.951 Å)
主引用文献Crystallization of recombinant green mamba rho-Da1a toxin during a lyophilization procedure and its structure determination.
Acta Crystallogr.,Sect.F, 69, 2013
2K2X
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Solution Structure of Tick Carboxypeptidase Inhibitor at pH 3.5
分子名称: Carboxypeptidase inhibitor
著者Pantoja-Uceda, D, Blanco, F.
登録日2008-04-15
公開日2009-01-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2JYT
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Human Granulin C, isomer 1
分子名称: Granulin-5
著者Tolkatchev, D, Wang, P, Chen, Z, Xu, P, Ni, F.
登録日2007-12-19
公開日2008-04-22
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities.
Protein Sci., 17, 2008
2JZP
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NMR solution structure of Kx5Q ProtL mutant
分子名称: Protein L
著者Lopez-Mendez, N, Tadeo, X, Castano, D, Pons, M, Millet Aguilar-Galindo, O.
登録日2008-01-11
公開日2009-01-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Protein stabilization and the hofmeister effect: the role of hydrophobic solvation
Biophys.J., 97, 2009
4IWP
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Crystal structure and mechanism of activation of TBK1
分子名称: N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1
著者Panne, D, Larabi, A.
登録日2013-01-24
公開日2013-03-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.065 Å)
主引用文献Crystal structure and mechanism of activation of TANK-binding kinase 1.
Cell Rep, 3, 2013
3OVJ
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Structure of an amyloid forming peptide KLVFFA from amyloid beta in complex with orange G
分子名称: 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid, KLVFFA hexapeptide segment from Amyloid beta
著者Landau, M, Eisenberg, D.
登録日2010-09-16
公開日2011-07-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Towards a pharmacophore for amyloid.
Plos Biol., 9, 2011
2K0A
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1H, 15N and 13C chemical shift assignments for Rds3 protein
分子名称: Pre-mRNA-splicing factor RDS3, ZINC ION
著者Loening, N, van Roon, A, Yang, J, Nagai, K, Neuhaus, D.
登録日2008-01-31
公開日2008-07-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3OIY
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Helicase domain of reverse gyrase from Thermotoga maritima
分子名称: CHLORIDE ION, PYROPHOSPHATE 2-, reverse gyrase helicase domain
著者Rudolph, M.G, Klostermeier, D.
登録日2010-08-20
公開日2010-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The latch modulates nucleotide and DNA binding to the helicase-like domain of Thermotoga maritima reverse gyrase and is required for positive DNA supercoiling.
Nucleic Acids Res., 39, 2011
2JOD
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Pac1-Rshort N-terminal EC domain Pacap(6-38) complex
分子名称: Pituitary adenylate cyclase-activating polypeptide, Pituitary adenylate cyclase-activating polypeptide type I receptor
著者Olejniczak, E.T, Sun, C, Song, D, Davis-Taber, R.A, Barrett, L.W, Scott, V.E, Richardson, P.L, Pereda-lopez, A, Uchic, M.E, Solomon, L.R, Lake, M.R, Walter, K.A, Hajduk, P.J.
登録日2007-03-07
公開日2007-05-22
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS.
Proc.Natl.Acad.Sci.Usa, 104, 2007

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