5FPO
| Structure of Bacterial DNA Ligase with small-molecule ligand 1H- indazol-7-amine (AT4213) in an alternate binding site. | 分子名称: | 1H-indazol-7-amine, DNA LIGASE | 著者 | Jhoti, H, Ludlow, R.F, Pathuri, P, Saini, H.K, Tickle, I.J, Tisi, D, Verdonk, M, Williams, P.A. | 登録日 | 2015-12-02 | 公開日 | 2015-12-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Detection of Secondary Binding Sites in Proteins Using Fragment Screening. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4DT5
| Crystal Structure of Rhagium inquisitor Antifreeze Protein | 分子名称: | Antifreeze protein, GLYCEROL, SULFATE ION | 著者 | Meng, W, Nguyen, J.B, Hakim, A, Thakral, D, Zhu, D.F. | 登録日 | 2012-02-20 | 公開日 | 2013-03-13 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Crystal structure of an insect antifreeze protein and its implications for ice binding. J.Biol.Chem., 288, 2013
|
|
7MLA
| Solution NMR structure of HDMX in complex with Zn and MCo-52-2 | 分子名称: | MCo-52-2, Protein Mdm4, ZINC ION | 著者 | Ramirez, L.S, Theophall, G, Chaudhuri, D, Camarero, J.C, Shekhtman, A. | 登録日 | 2021-04-28 | 公開日 | 2022-05-04 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of HDMX in complex with Zn and cyclotide 52-2 To Be Published
|
|
4DW8
| Crystal structure of a haloacid dehalogenase-like hydrolase (Target EFI-900331) from Bacteroides thetaiotaomicron with bound Na crystal form I | 分子名称: | Haloacid dehalogenase-like hydrolase, SODIUM ION, UNKNOWN LIGAND | 著者 | Vetting, M.W, Wasserman, S.R, Morisco, L.L, Sojitra, S, Allen, K.N, Dunaway-Mariano, D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-02-24 | 公開日 | 2012-03-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.502 Å) | 主引用文献 | Crystal structure of a haloacid dehalogenase-like hydrolase (Target EFI-900331) from Bacteroides thetaiotaomicron with bound Na crystal form I To be Published
|
|
7WDA
| Crystal structure LpqY in complex with Trehalose from Mycobacterium tuberculosis | 分子名称: | SULFATE ION, Trehalose-binding lipoprotein LpqY, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | 著者 | Sharma, D, Das, U. | 登録日 | 2021-12-21 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Structural analysis of LpqY, a substrate-binding protein from the SugABC transporter of Mycobacterium tuberculosis, provides insights into its trehalose specificity. Acta Crystallogr D Struct Biol, 78, 2022
|
|
7WCJ
| Crystal structure LpqY from Mycobacterium tuberculosis | 分子名称: | SULFATE ION, Trehalose-binding lipoprotein LpqY | 著者 | Sharma, D, Das, U. | 登録日 | 2021-12-20 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Structural analysis of LpqY, a substrate-binding protein from the SugABC transporter of Mycobacterium tuberculosis, provides insights into its trehalose specificity. Acta Crystallogr D Struct Biol, 78, 2022
|
|
7VZB
| Cryo-EM structure of C22:0-CoA bound human very long-chain fatty acid ABC transporter ABCD1 | 分子名称: | CHOLESTEROL HEMISUCCINATE, Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] docosanethioate | 著者 | Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z. | 登録日 | 2021-11-15 | 公開日 | 2022-05-18 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1. Nat Commun, 13, 2022
|
|
7MN2
| Rules for designing protein fold switches and their implications for the folding code | 分子名称: | Sb2 | 著者 | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | 登録日 | 2021-04-30 | 公開日 | 2022-05-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
|
|
7WGW
| NMR Solution Structure of a cGMP Fill-in Vacancy G-quadruplex Formed in the Oxidized BLM Gene Promoter | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, DNA (20-MER) | 著者 | Wang, K.B, Liu, Y, Li, Y, Li, J, Dickerhoff, J, Yang, M.H, Yang, D, Kong, L.Y. | 登録日 | 2021-12-29 | 公開日 | 2022-05-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter. J.Am.Chem.Soc., 144, 2022
|
|
7W9P
| Cryo-EM structure of human Nav1.7(E406K) in complex with auxiliary beta subunits, huwentoxin-IV and saxitoxin (S6IV pi helix conformer) | 分子名称: | (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | 著者 | Yan, N, Huang, G, Liu, D, Wei, P, Shen, H. | 登録日 | 2021-12-10 | 公開日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | High-resolution structures of human Na v 1.7 reveal gating modulation through alpha-pi helical transition of S6 IV. Cell Rep, 39, 2022
|
|
3SBA
| Zn-mediated Hexamer of T4 Lysozyme R76H/R80H by Synthetic Symmetrization | 分子名称: | CHLORIDE ION, Lysozyme, ZINC ION | 著者 | Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-03 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
|
|
7MJC
| |
7W9M
| Cryo-EM structure of human Nav1.7(E406K) in complex with auxiliary beta subunits, ProTx-II and tetrodotoxin (S6IV pi helix conformer) | 分子名称: | (1R,5R,6R,7R,9S,11S,12S,13S,14S)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name), 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Huang, G, Liu, D, Wei, P, Shen, H. | 登録日 | 2021-12-10 | 公開日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | High-resolution structures of human Na v 1.7 reveal gating modulation through alpha-pi helical transition of S6 IV. Cell Rep, 39, 2022
|
|
7MJD
| Crystal Structure Analysis of ALDH1B1 | 分子名称: | 8-(2-methoxyphenyl)-10-(4-phenylphenyl)-1$l^{4},8-diazabicyclo[5.3.0]deca-1(7),9-diene, Aldehyde dehydrogenase X, mitochondrial, ... | 著者 | Fernandez, D, Chen, J.K. | 登録日 | 2021-04-20 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Inhibitors targeted to aldehyde dehydrogenase Nat.Chem.Biol., 2022
|
|
7W9L
| Cryo-EM structure of human Nav1.7(E406K)-beta1-beta2 complex | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | 著者 | Yan, N, Huang, G, Liu, D, Wei, P, Shen, H. | 登録日 | 2021-12-10 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | High-resolution structures of human Na v 1.7 reveal gating modulation through alpha-pi helical transition of S6 IV. Cell Rep, 39, 2022
|
|
4ETK
| Crystal Structure of E6A/L130D/A155H variant of de novo designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR186 | 分子名称: | De novo designed serine hydrolase, SODIUM ION | 著者 | Kuzin, A, Su, M, Seetharaman, J, Kornhaber, K, Kornhaber, G, Rajagopalan, S, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-04-24 | 公開日 | 2012-06-13 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014
|
|
3SET
| Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I) | 分子名称: | Maltose-binding periplasmic protein, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-11 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
|
|
7W9T
| Cryo-EM structure of human Nav1.7(E406K) in complex with auxiliary beta subunits, huwentoxin-IV and saxitoxin (S6IV alpha helix conformer) | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | 著者 | Yan, N, Huang, G, Liu, D, Wei, P. | 登録日 | 2021-12-10 | 公開日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | High-resolution structures of human Na v 1.7 reveal gating modulation through alpha-pi helical transition of S6 IV. Cell Rep, 39, 2022
|
|
4NOG
| Crystal structure of a putative ornithine aminotransferase from Toxoplasma gondii ME49 in complex with pyrodoxal-5'-phosphate | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, BETA-MERCAPTOETHANOL, ... | 著者 | Filippova, E.V, Halavaty, A, Ruan, J, Shuvalova, L, Flores, K, Dubrovska, I, Ngo, H, Shanmugam, D, Roos, D, Anderson, W.F, Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2013-11-19 | 公開日 | 2013-12-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii . Front Cell Infect Microbiol, 8, 2018
|
|
4EIW
| Whole cytosolic region of atp-dependent metalloprotease FtsH (G399L) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent zinc metalloprotease FtsH | 著者 | Suno, R, Niwa, H, Tsuchiya, D, Yoshida, M, Morikawa, K. | 登録日 | 2012-04-06 | 公開日 | 2012-06-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Structure of the whole cytosolic region of ATP-dependent protease FtsH Mol.Cell, 22, 2006
|
|
7LJ3
| Structure of human transfer RNA visualized in the cytomegalovirus, a DNA virus | 分子名称: | RNA (75-MER), Tegument protein pp150 | 著者 | Liu, Y.T, Strugatsky, D, Liu, W, Zhou, Z.H. | 登録日 | 2021-01-28 | 公開日 | 2021-11-17 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150. Nat Commun, 12, 2021
|
|
3SES
| Cu-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization | 分子名称: | CHLORIDE ION, COPPER (II) ION, Maltose-binding periplasmic protein, ... | 著者 | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-11 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
|
|
3S9B
| |
7LI9
| |
7LIA
| |