1JZP
| Modified Peptide A (D18-A1) of the Rabbit Skeletal Dihydropyridine Receptor | 分子名称: | Skeletal Dihydropydrine Receptor | 著者 | Green, D, Pace, S, Sakowska, M, Dulhunty, A.F, Casarotto, M.G. | 登録日 | 2001-09-17 | 公開日 | 2002-03-20 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | The three-dimensional structural surface of two beta-sheet scorpion toxins mimics that of an alpha-helical dihydropyridine receptor segment. Biochem.J., 370, 2003
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8DPR
| Crystal structure of SARS-CoV-2 main protease in complex with inhibitor TKB-248 | 分子名称: | 2,2,2-trifluoro-N-{(2S)-1-[(1R,2S,5S)-2-({(2S)-1-(4-fluoro-1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}carbamothioyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl]-3,3-dimethyl-1-oxobutan-2-yl}acetamide, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, ... | 著者 | Bulut, H, Hayashi, H, Tsuji, K, Kuwata, N, Das, D, Tamamura, H, Mitsuya, H. | 登録日 | 2022-07-16 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification of SARS-CoV-2 M pro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2. Nat Commun, 14, 2023
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5UTM
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8DOY
| Crystal structure of SARS-CoV-2 main protease in complex with an inhibitor TKB-198 | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3C-like proteinase nsp5, ... | 著者 | Bulut, H, Hayashi, H, Tsuji, K, Kuwata, N, Das, D, Tamamura, H, Mitsuya, H. | 登録日 | 2022-07-14 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Potent and biostable inhibitors of the main protease of SARS-CoV-2. Iscience, 25, 2022
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8DTL
| Cryo-EM structure of insulin receptor (IR) bound with S597 peptide | 分子名称: | Insulin mimetic peptide S597, Insulin receptor | 著者 | Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E. | 登録日 | 2022-07-25 | 公開日 | 2022-09-07 | 最終更新日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Activation of the insulin receptor by an insulin mimetic peptide. Nat Commun, 13, 2022
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5UUV
| Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with a product IMP and the inhibitor P182 | 分子名称: | GLYCEROL, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase, ... | 著者 | Kim, Y, Maltseva, N, Mulligan, R, Makowska-Grzyska, M, Gu, M, Gollapalli, D, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-02-17 | 公開日 | 2017-03-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from
Bacillus anthracis in the complex with a product IMP and the inhibitor P182 To Be Published
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4RAN
| Aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, Plasmodium falciparum and vivax 6-oxopurine phosphoribosyltransferases and their pro-drugs as antimalarial agents | 分子名称: | (2-{[2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl](3-aminopropyl)amino}ethyl)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION | 著者 | Keough, D.T, Hockova, D, Janeba, Z, Wang, T.-H, Naesens, L, Edstein, M.D, Chavchich, M, Guddat, L.W. | 登録日 | 2014-09-10 | 公開日 | 2015-01-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.549 Å) | 主引用文献 | Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6-Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents. J.Med.Chem., 58, 2015
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7R3B
| S-adenosylmethionine synthetase from Lactobacillus plantarum complexed with AMPPNP, methionine and SAM | 分子名称: | (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, PHENYLALANINE, ... | 著者 | Shahar, A, Kleiner, D, Bershtein, S, Zarivach, R. | 登録日 | 2022-02-07 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | 主引用文献 | Evolution of homo-oligomerization of methionine S-adenosyltransferases is replete with structure-function constrains. Protein Sci., 31, 2022
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8DTM
| Cryo-EM structure of insulin receptor (IR) bound with S597 component 2 | 分子名称: | Insulin mimetic peptide S597 component 2, Insulin receptor | 著者 | Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E. | 登録日 | 2022-07-26 | 公開日 | 2022-09-07 | 最終更新日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Activation of the insulin receptor by an insulin mimetic peptide. Nat Commun, 13, 2022
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1M7L
| Solution Structure of the Coiled-Coil Trimerization Domain from Lung Surfactant Protein D | 分子名称: | Pulmonary surfactant-associated protein D | 著者 | Kovacs, H, O'Donoghue, S.I, Hoppe, H.-J, Comfort, D, Reid, K.B.M, Campbell, I.D, Nilges, M. | 登録日 | 2002-07-22 | 公開日 | 2002-11-27 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the coiled-coil trimerization domain from lung surfactant protein D J.BIOMOL.NMR, 24, 2002
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1M1R
| Reduced p222 crystal structure of the tetraheme cytochrome c of Shewanella oneidensis MR1 | 分子名称: | HEME C, SMALL tetraheme cytochrome c, SULFATE ION | 著者 | Leys, D, Meyer, T.E, Tsapin, A.I, Nealson, K.H, Cusanovich, M.A, Van Beeumen, J.J. | 登録日 | 2002-06-20 | 公開日 | 2002-08-14 | 最終更新日 | 2021-03-03 | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | 主引用文献 | Crystal structures at atomic resolution reveal the novel concept of 'electron-harvesting' as a role for the small tetraheme cytochrome c J.Biol.Chem., 277, 2002
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7R2W
| Mutant S-adenosylmethionine synthetase from E.coli complexed with AMPPNP and methionine | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, POTASSIUM ION, ... | 著者 | Shahar, A, Kleiner, D, Bershtein, S, Zarivach, R. | 登録日 | 2022-02-06 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Evolution of homo-oligomerization of methionine S-adenosyltransferases is replete with structure-function constrains. Protein Sci., 31, 2022
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1M8V
| Structure of Pyrococcus abyssii Sm Protein in Complex with a Uridine Heptamer | 分子名称: | 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', CALCIUM ION, PUTATIVE SNRNP SM-LIKE PROTEIN, ... | 著者 | Thore, S, Mayer, C, Sauter, C, Weeks, S, Suck, D. | 登録日 | 2002-07-26 | 公開日 | 2003-02-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Pyrococcus abyssii Sm core and its Complex with RNA: Common Features of RNA-binding in Archaea and Eukarya J.Biol.Chem., 278, 2003
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7RCQ
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4RJI
| Acetolactate synthase from Bacillus subtilis bound to ThDP - crystal form I | 分子名称: | Acetolactate synthase, MAGNESIUM ION, TETRAETHYLENE GLYCOL, ... | 著者 | Sommer, B, von Moeller, H, Haack, M, Qoura, F, Langner, C, Bourenkov, G, Garbe, D, Brueck, T, Loll, B. | 登録日 | 2014-10-09 | 公開日 | 2014-10-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Detailed Structure-Function Correlations of Bacillus subtilis Acetolactate Synthase. Chembiochem, 16, 2015
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1MAZ
| X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH | 分子名称: | Bcl-2-like protein 1 | 著者 | Muchmore, S.W, Sattler, M, Liang, H, Meadows, R.P, Harlan, J.E, Yoon, H.S, Nettesheim, D, Chang, B.S, Thompson, C.B, Wong, S.L, Ng, S.C, Fesik, S.W. | 登録日 | 1996-04-09 | 公開日 | 1997-04-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature, 381, 1996
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7RAZ
| Small conductance mechanosensitive channel MscS | 分子名称: | PHOSPHATIDYLETHANOLAMINE, Small-conductance mechanosensitive channel | 著者 | Catalano, C, Ben-Hail, D, Qiu, W, des Georges, A, Guo, Y. | 登録日 | 2021-07-05 | 公開日 | 2022-07-13 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Small conductance mechanosensitive channel MscS To Be Published
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4RJK
| Acetolactate synthase from Bacillus subtilis bound to LThDP - crystal form II | 分子名称: | 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, Acetolactate synthase, MAGNESIUM ION, ... | 著者 | Sommer, B, von Moeller, H, Haack, M, Qoura, F, Langner, C, Bourenkov, G, Garbe, D, Brueck, T, Loll, B. | 登録日 | 2014-10-09 | 公開日 | 2014-10-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Detailed Structure-Function Correlations of Bacillus subtilis Acetolactate Synthase. Chembiochem, 16, 2015
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4RG8
| Structural and biochemical studies of a moderately thermophilic Exonuclease I from Methylocaldum szegediense | 分子名称: | Exonuclease I, MAGNESIUM ION | 著者 | Fei, L, Tian, S, Moysey, R, Misca, M, Barker, J.J, Smith, M.A, McEwan, P.A, Pilka, E.S, Crawley, L, Evans, T, Sun, D. | 登録日 | 2014-09-29 | 公開日 | 2015-02-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural and Biochemical Studies of a Moderately Thermophilic Exonuclease I from Methylocaldum szegediense. Plos One, 10, 2015
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5V5C
| VQIINK, Structure of the amyloid-spine from microtubule associated protein tau Repeat 2 | 分子名称: | Microtubule-associated protein tau | 著者 | Seidler, P.M, Sawaya, M.R, Rodriguez, J.A, Eisenberg, D.S, Cascio, D, Boyer, D.R. | 登録日 | 2017-03-14 | 公開日 | 2018-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.25 Å) | 主引用文献 | Structure-based inhibitors of tau aggregation. Nat Chem, 10, 2018
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1LXJ
| X-RAY STRUCTURE OF YBL001c NORTHEAST STRUCTURAL GENOMICS (NESG) CONSORTIUM TARGET YTYst72 | 分子名称: | HYPOTHETICAL 11.5KDA PROTEIN IN HTB2-NTH2 INTERGENIC REGION, SULFATE ION | 著者 | Tao, X, Khayat, R, Christendat, D, Savchenko, A, Xu, X, Edwards, A, Arrowsmith, C.H, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2002-06-05 | 公開日 | 2003-07-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | CRYSTAL STRUCTURES OF MTH1187 AND ITS YEAST ORTHOLOG YBL001C Proteins, 52, 2003
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4RJJ
| Acetolactate synthase from Bacillus subtilis bound to ThDP - crystal form II | 分子名称: | ACETATE ION, Acetolactate synthase, MAGNESIUM ION, ... | 著者 | Sommer, B, von Moeller, H, Haack, M, Qoura, F, Langner, C, Bourenkov, G, Garbe, D, Brueck, T, Loll, B. | 登録日 | 2014-10-09 | 公開日 | 2014-10-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Detailed Structure-Function Correlations of Bacillus subtilis Acetolactate Synthase. Chembiochem, 16, 2015
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7RGC
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4RGF
| Crystal structure of the in-line aligned env22 twister ribozyme soaked with Mn2+ | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... | 著者 | Ren, A, Rajashankar, K.R, Simanshu, D, Patel, D. | 登録日 | 2014-09-30 | 公開日 | 2014-12-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2008 Å) | 主引用文献 | In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme. Nat Commun, 5, 2014
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1M0G
| Solution structure of the alpha domain of mt_nc | 分子名称: | CADMIUM ION, metallothionein MT_nc | 著者 | Capasso, C, Carginale, V, Crescenzi, O, Di Maro, D, Parisi, E, Spadaccini, R, Temussi, P.A. | 登録日 | 2002-06-13 | 公開日 | 2003-05-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of MT_nc, a Novel Metallothionein from the Antarctic Fish Notothenia coriiceps. Structure, 11, 2003
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