8EDQ
 
 | | E. coli pyruvate kinase (PykF) I264F | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pyruvate kinase, SULFATE ION | | 著者 | Donovan, K.A, Coombes, D, Dobson, R.C.J, Cooper, T.F. | | 登録日 | 2022-09-05 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | Beneficial mutations occurring in E. coli pyruvate kinase afford new allosteric mechanisms leading to faster resumption of growth
To Be Published
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7RA3
 | | cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP | | 分子名称: | Gastric inhibitory polypeptide, Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Sun, B, Kobilka, B.K, Sloop, K.W, Feng, D, Kobilka, T.S. | | 登録日 | 2021-06-29 | | 公開日 | 2022-04-13 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Structural determinants of dual incretin receptor agonism by tirzepatide.
Proc.Natl.Acad.Sci.USA, 119, 2022
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5UKH
 | | Structure of TelC from Streptococcus intermedius B196 | | 分子名称: | CALCIUM ION, Uncharacterized protein | | 著者 | Whitney, J.C, Ching, M.Q, Bryant, D, Mougous, J.D. | | 登録日 | 2017-01-22 | | 公開日 | 2017-07-26 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | A broadly distributed toxin family mediates contact-dependent antagonism between gram-positive bacteria.
Elife, 6, 2017
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8EF5
 | | Fentanyl-bound mu-opioid receptor-Gi complex | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | | 登録日 | 2022-09-08 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
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5UQG
 | | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p200 | | 分子名称: | 1,2-ETHANEDIOL, 3-(2-{[(4-chlorophenyl)carbamoyl]amino}propan-2-yl)-N-hydroxybenzene-1-carboximidamide, INOSINIC ACID, ... | | 著者 | Kim, Y, Maltseva, N, Makowska-Grzyska, M, Gu, M, Gollapalli, D, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2017-02-08 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p200
To Be Published
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8EF6
 | | Morphine-bound mu-opioid receptor-Gi complex | | 分子名称: | (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | | 登録日 | 2022-09-08 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
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5URF
 | | The structure of human bocavirus 1 | | 分子名称: | viral protein 3 | | 著者 | Mietzsch, M, Kailasan, S, Garrison, J, Ilyas, M, Chipman, P, Kandola, K, Jansen, M, Spear, J, Sousa, D, McKenna, R, Soderlund-Venermo, M, Baker, T, Agbandje-McKenna, M. | | 登録日 | 2017-02-10 | | 公開日 | 2017-03-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural Insights into Human Bocaparvoviruses.
J. Virol., 91, 2017
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4R6B
 | | Rational Design of Enhanced Photoresistance in a Photoswitchable Fluorescent Protein | | 分子名称: | Green to red photoconvertible GFP-like protein EosFP, SULFATE ION, SULFITE ION | | 著者 | Duan, C, Adam, V, Byrdin, M, Bourgeois, D. | | 登録日 | 2014-08-23 | | 公開日 | 2015-02-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Rational design of enhanced photoresistance in a photoswitchable fluorescent protein.
Methods Appl Fluoresc, 3, 2015
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8EFO
 | | PZM21-bound mu-opioid receptor-Gi complex | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | | 登録日 | 2022-09-08 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
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8EFL
 | | SR17018-bound mu-opioid receptor-Gi complex | | 分子名称: | 5,6-dichloro-1-{1-[(4-chlorophenyl)methyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | | 登録日 | 2022-09-08 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
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7R6N
 | | Exon-free state of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic trimeric construct | | 分子名称: | Group I intron, MAGNESIUM ION | | 著者 | Thelot, F, Liu, D, Liao, M, Yin, P. | | 登録日 | 2021-06-22 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly.
Nat.Methods, 19, 2022
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8EFB
 | | Oliceridine-bound mu-opioid receptor-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | | 登録日 | 2022-09-08 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
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4RAO
 | | Aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, Plasmodium falciparum and vivax 6-oxopurine phosphoribosyltransferases and their pro-drugs as antimalarial agents | | 分子名称: | (2-{[2-(6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl](2-{[(E)-2-phosphonoethenyl]oxy}ethyl)amino}ethyl)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION | | 著者 | Keough, D.T, Hockova, D, Janeba, Z, Wang, T.-H, Naesens, L, Edstein, M.D, Chavchich, M, Guddat, L.W. | | 登録日 | 2014-09-10 | | 公開日 | 2015-01-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.871 Å) | | 主引用文献 | Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6-Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents.
J.Med.Chem., 58, 2015
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4LJD
 | | Structure of a photobleached state of IrisFP under low intensity laser-light | | 分子名称: | Green to red photoconvertible GPF-like protein EosFP, SULFATE ION, SULFITE ION | | 著者 | Duan, C, Adam, V, Byrdin, M, Ridard, J, Kieffer-Jacquinod, S, Morlot, C, Arcizet, D, Demachy, I, Bourgeois, D. | | 登録日 | 2013-07-04 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein.
J.Am.Chem.Soc., 135, 2013
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1KS5
 | | Structure of Aspergillus niger endoglucanase | | 分子名称: | Endoglucanase A | | 著者 | Khademi, S, Zhang, D, Swanson, S.M, Wartenberg, A, Witte, C, Meyer, E.F. | | 登録日 | 2002-01-10 | | 公開日 | 2003-01-21 | | 最終更新日 | 2017-02-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Determination of the structure of an endoglucanase from Aspergillus niger and its mode of inhibition by palladium chloride.
Acta Crystallogr.,Sect.D, 58, 2002
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4QYX
 | | Crystal structure of YDR533Cp | | 分子名称: | Probable chaperone protein HSP31 | | 著者 | Wilson, M.A, Amour, S.T, Collins, J.L, Ringe, D, Petsko, G.A. | | 登録日 | 2014-07-26 | | 公開日 | 2014-08-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: A member of the DJ-1/ThiJ/PfpI superfamily.
Proc.Natl.Acad.Sci.USA, 101, 2004
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8EFQ
 | | DAMGO-bound mu-opioid receptor-Gi complex | | 分子名称: | DAMGO, ETHANOLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | | 登録日 | 2022-09-08 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor.
Cell, 185, 2022
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7R6M
 | | Post-2S intermediate of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic dimeric construct | | 分子名称: | Group I intron, Ligated exon mimic of the Group I intron, MAGNESIUM ION | | 著者 | Thelot, F, Liu, D, Liao, M, Yin, P. | | 登録日 | 2021-06-22 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly.
Nat.Methods, 19, 2022
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8EDT
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5UY6
 | | Crystal Structure of the Human CAMKK2B | | 分子名称: | 2-cyclopentyl-4-(5-phenylfuro[2,3-b]pyridin-3-yl)benzoic acid, Calcium/calmodulin-dependent protein kinase kinase 2 | | 著者 | Counago, R.M, Dewry, D, Bountra, C, Arruda, P, Edwards, A.M, Gileadi, O, Structural Genomics Consortium (SGC) | | 登録日 | 2017-02-23 | | 公開日 | 2017-03-29 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of the Human CAMKK2B
To Be Published
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8EEX
 | | Cas7-11 in complex with Csx29 | | 分子名称: | Cas7-11, Csx29, ZINC ION, ... | | 著者 | Demircioglu, F.E, Wilkinson, M.E, Strecker, J, Li, D, Faure, G, Macrae, R.K, Zhang, F. | | 登録日 | 2022-09-07 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | RNA-activated protein cleavage with a CRISPR-associated endopeptidase.
Science, 378, 2022
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7R6L
 | | 5 prime exon-free pre-2S intermediate of the Tetrahymena group I intron, symmetry-expanded monomer from a synthetic dimeric construct | | 分子名称: | Group I intron, 3 prime fragment plus 3 prime exon, 5 prime fragment, ... | | 著者 | Thelot, F, Liu, D, Liao, M, Yin, P. | | 登録日 | 2021-06-22 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Sub-3- angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly.
Nat.Methods, 19, 2022
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8F09
 | | Crystal structure of a trimethoprim-resistant dihydrofolate reductase (DHFR) enzyme from an uncultured soil bacterium | | 分子名称: | Dihydrofolate reductase, SULFATE ION | | 著者 | Stogios, P.J, Evdokimova, D, Borek, D, Di Leo, R, Semper, C, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID) | | 登録日 | 2022-11-02 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structure of a trimethoprim-resistant dihydrofolate reductase (DHFR) enzyme from an uncultured soil bacterium
To Be Published
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5UJH
 | | ov-GRN12-34 | | 分子名称: | Granulin | | 著者 | Bansal, P, Smout, M, Wilson, D, Caceres, C.C, Dastpeyman, M, Sotillo, J, Seifert, J, Brindley, P, Loukas, A, Daly, N. | | 登録日 | 2017-01-18 | | 公開日 | 2018-01-24 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold.
J. Med. Chem., 60, 2017
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8EDS
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