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PDB: 566 results

2GN8
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Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADP and UDP
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, UDP-GlcNAc C6 dehydratase, ...
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2006-04-09
Release date:2006-05-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity.
J.Biol.Chem., 281, 2006
1GFI
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STRUCTURES OF ACTIVE CONFORMATIONS OF GI ALPHA 1 AND THE MECHANISM OF GTP HYDROLYSIS
Descriptor: GUANINE NUCLEOTIDE-BINDING PROTEIN G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Coleman, D.E, Berghuis, A.M, Sprang, S.R.
Deposit date:1994-11-11
Release date:1995-03-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.
Science, 265, 1994
3G8A
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BU of 3g8a by Molmil
T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoHcy in space group P61
Descriptor: Ribosomal RNA small subunit methyltransferase G, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Demirci, H, Gregory, S.T, Belardinelli, R, Gualerzi, C, Dahlberg, A.E, Jogl, G.
Deposit date:2009-02-11
Release date:2009-06-30
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG
Rna, 15, 2009
1E5A
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BU of 1e5a by Molmil
Structure of human transthyretin complexed with bromophenols: a new mode of binding
Descriptor: 2,4,6-TRIBROMOPHENOL, TRANSTHYRETIN
Authors:Ghosh, M, Meerts, I.A.T.M, Cook, A, Bergman, A, Brouwer, A, Johnson, L.N.
Deposit date:2000-07-20
Release date:2000-08-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Human Transthyretin Complexed with Bromophenols : A New Mode of Binding
Acta Crystallogr.,Sect.D, 56, 2000
2GNA
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Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADP and UDP-Gal
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GALACTOSE-URIDINE-5'-DIPHOSPHATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2006-04-09
Release date:2006-05-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity.
J.Biol.Chem., 281, 2006
1J7I
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Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Apoenzyme
Descriptor: AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE
Authors:Burk, D.L, Hon, W.C, Leung, A.K.-W, Berghuis, A.M.
Deposit date:2001-05-16
Release date:2001-08-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase.
Biochemistry, 40, 2001
2B61
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BU of 2b61 by Molmil
Crystal Structure of Homoserine Transacetylase
Descriptor: Homoserine O-acetyltransferase
Authors:Mirza, I.A, Nazi, I, Korczynska, M, Wright, G.D, Berghuis, A.M.
Deposit date:2005-09-29
Release date:2005-11-15
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of Homoserine Transacetylase from Haemophilus influenzae Reveals a New Family of alpha/beta-Hydrolases
Biochemistry, 44, 2005
2CM0
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The PUB domain functions as a p97 binding module in human peptide N-glycanase.
Descriptor: BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, PEPTIDE N-GLYCANASE HOMOLOG
Authors:Allen, M.D, Buchberger, A, Bycroft, M.
Deposit date:2006-05-03
Release date:2006-06-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Pub Domain Functions as a P97 Binding Module in Human Peptide N-Glycanase.
J.Biol.Chem., 281, 2006
1QY1
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BU of 1qy1 by Molmil
Thermodynamics of Binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the Major Urinary Protein
Descriptor: 2-ISOBUTYL-3-METHOXYPYRAZINE, CADMIUM ION, Major Urinary Protein, ...
Authors:Bingham, R.J, Findlay, J.B.C, Hsieh, S.-Y, Kalverda, A.P, Kjellberg, A, Perazzolo, C, Phillips, S.E.V, Seshadri, K, Trinh, C.H, Turnbull, W.B, Bodenhausen, G, Homans, S.W.
Deposit date:2003-09-09
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Thermodynamics of Binding of 2-Methoxy-3-isopropylpyrazine and 2-Methoxy-3-isobutylpyrazine to the Major Urinary Protein.
J.Am.Chem.Soc., 126, 2004
1Q33
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Crystal structure of human ADP-ribose pyrophosphatase NUDT9
Descriptor: ADP-ribose pyrophosphatase, SULFATE ION, beta-D-glucopyranose
Authors:Shen, B.W, Perraud, A.L, Scharenberg, A, Stoddard, B.L.
Deposit date:2003-07-28
Release date:2003-09-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:The Crystal Structure and Mutational Analysis of Human NUDT9
J.Mol.Biol., 332, 2003
1EBU
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HOMOSERINE DEHYDROGENASE COMPLEX WITH NAD ANALOGUE AND L-HOMOSERINE
Descriptor: 3-AMINOMETHYL-PYRIDINIUM-ADENINE-DINUCLEOTIDE, HOMOSERINE DEHYDROGENASE, L-HOMOSERINE, ...
Authors:DeLaBarre, B, Thompson, P.R, Wright, G.D, Berghuis, A.M.
Deposit date:2000-01-24
Release date:2000-03-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.
Nat.Struct.Biol., 7, 2000
6NY0
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Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-(4-{3-[4-(6-carboxy-1H-benzimidazol-2-yl)phenoxy]-2-hydroxypropoxy}phenyl)-1H-benzimidazole-5-carboxylic acid, Dihydrofolate reductase type 2, ...
Authors:Yachnin, B.J, Berghuis, A.M.
Deposit date:2019-02-10
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues.
Acs Omega, 4, 2019
6NXZ
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Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-[4-[(2~{R})-4-[4-(6-carboxy-1~{H}-benzimidazol-2-yl)phenoxy]-2-oxidanyl-butoxy]phenyl]-1~{H}-benzimidazole-5-carboxylic acid, Dihydrofolate reductase type 2, ...
Authors:Yachnin, B.J, Berghuis, A.M.
Deposit date:2019-02-10
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues.
Acs Omega, 4, 2019
1SB8
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BU of 1sb8 by Molmil
Crystal structure of Pseudomonas aeruginosa UDP-N-acetylglucosamine 4-epimerase complexed with UDP-N-acetylgalactosamine
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE, wbpP
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2004-02-10
Release date:2004-05-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of WbpP, a Genuine UDP-N-acetylglucosamine 4-Epimerase from Pseudomonas aeruginosa: SUBSTRATE SPECIFICITY IN UDP-HEXOSE 4-EPIMERASES.
J.Biol.Chem., 279, 2004
1GIL
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BU of 1gil by Molmil
STRUCTURE OF ACTIVE CONFORMATIONS OF GIA1 AND THE MECHANISM OF GTP HYDROLYSIS
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, G PROTEIN GI ALPHA 1, MAGNESIUM ION
Authors:Coleman, D.E, Berghuis, A.M, Sprang, S.R.
Deposit date:1995-01-02
Release date:1995-02-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.
Science, 265, 1994
1SB9
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BU of 1sb9 by Molmil
Crystal structure of Pseudomonas aeruginosa UDP-N-acetylglucosamine 4-epimerase complexed with UDP-glucose
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-GLUCOSE, wbpP
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2004-02-10
Release date:2004-05-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of WbpP, a Genuine UDP-N-acetylglucosamine 4-Epimerase from Pseudomonas aeruginosa: SUBSTRATE SPECIFICITY IN UDP-HEXOSE 4-EPIMERASES.
J.Biol.Chem., 279, 2004
1BXE
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BU of 1bxe by Molmil
RIBOSOMAL PROTEIN L22 FROM THERMUS THERMOPHILUS
Descriptor: CHLORIDE ION, PROTEIN (RIBOSOMAL PROTEIN L22)
Authors:Unge, J, Aberg, A, Al-Karadaghi, S, Nikulin, A, Nikonov, S, Davydova, N, Nevskaya, N, Garber, M, Liljas, A.
Deposit date:1998-10-02
Release date:1998-10-07
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance.
Structure, 6, 1998
2B0Q
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BU of 2b0q by Molmil
Crystal Structure Of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Neomycin B Complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Aminoglycoside 3'-phosphotransferase, MAGNESIUM ION, ...
Authors:Fong, D.H, Berghuis, A.M.
Deposit date:2005-09-14
Release date:2005-09-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry.
Embo J., 21, 2002
1TDQ
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BU of 1tdq by Molmil
Structural basis for the interactions between tenascins and the C-type lectin domains from lecticans: evidence for a cross-linking role for tenascins
Descriptor: Aggrecan core protein, CALCIUM ION, Tenascin-R
Authors:Lundell, A, Olin, A.I, Moergelin, M, al-Karadaghi, S, Aspberg, A, Logan, D.T.
Deposit date:2004-05-24
Release date:2004-08-31
Last modified:2021-03-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins
Structure, 12, 2004
2B7L
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BU of 2b7l by Molmil
Crystal Structure of CTP:Glycerol-3-Phosphate Cytidylyltransferase from Staphylococcus aureus
Descriptor: glycerol-3-phosphate cytidylyltransferase
Authors:Fong, D.H, Yim, V.C.-N, D'Elia, M.A, Brown, E.D, Berghuis, A.M.
Deposit date:2005-10-04
Release date:2006-06-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of CTP:glycerol-3-phosphate cytidylyltransferase from Staphylococcus aureus: examination of structural basis for kinetic mechanism.
Biochim.Biophys.Acta, 1764, 2006
1PFR
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BU of 1pfr by Molmil
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN
Descriptor: FE (III) ION, MERCURY (II) ION, PROTEIN R2 OF RIBONUCLEOTIDE REDUCTASE
Authors:Logan, D.T, Su, X.D, Aberg, A, Regnstrom, K, Hajdu, J, Eklund, H, Nordlund, P.
Deposit date:1996-12-03
Release date:1997-03-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site.
Structure, 4, 1996
2CCQ
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The PUB domain functions as a p97 binding module in human peptide N-glycanase.
Descriptor: GLYCEROL, PEPTIDE N-GLYCANASE HOMOLOG
Authors:Allen, M.D, Buchberger, A, Bycroft, M.
Deposit date:2006-01-17
Release date:2006-06-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Pub Domain Functions as a P97 Binding Module in Human Peptide N-Glycanase.
J.Biol.Chem., 281, 2006
2MAI
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BU of 2mai by Molmil
NMR structure of lassomycin
Descriptor: Lassomycin
Authors:Gavrish, E, Sit, C.S, Kandror, O, Spoering, A, Peoples, A, Ling, L, Fetterman, A, Hughes, D, Cao, S, Bissell, A, Torrey, H, Akopian, T, Mueller, A, Epstein, S, Goldberg, A, Clardy, J, Lewis, K.
Deposit date:2013-07-09
Release date:2014-05-07
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2.
Chem.Biol., 21, 2014
1QY2
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BU of 1qy2 by Molmil
Thermodynamics of Binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the Major Urinary Protein
Descriptor: 2-ISOPROPYL-3-METHOXYPYRAZINE, CADMIUM ION, Major Urinary Protein, ...
Authors:Bingham, R.J, Findlay, J.B.C, Hsieh, S.-Y, Kalverda, A.P, Kjellberg, A, Perazzolo, C, Phillips, S.E.V, Seshadri, K, Trinh, C.H, Turnbull, W.B, Bodenhausen, G, Homans, S.W.
Deposit date:2003-09-09
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Thermodynamics of Binding of 2-Methoxy-3-isopropylpyrazine and 2-Methoxy-3-isobutylpyrazine to the Major Urinary Protein.
J.Am.Chem.Soc., 126, 2004
6PPO
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BU of 6ppo by Molmil
Rhinovirus C15 complexed with domain I of receptor CDHR3
Descriptor: CALCIUM ION, Cadherin-related family member 3, Capsid protein VP1, ...
Authors:Sun, Y, Watters, K, Klose, T, Palmenberg, A.C.
Deposit date:2019-07-08
Release date:2020-03-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor.
Proc.Natl.Acad.Sci.USA, 117, 2020

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