5UYQ
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![BU of 5uyq by Molmil](/molmil-images/mine/5uyq) | 70S ribosome bound with near-cognate ternary complex base-paired to A site codon, closed 30S (Structure III-nc) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. | 登録日 | 2017-02-24 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
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4AWD
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![BU of 4awd by Molmil](/molmil-images/mine/4awd) | Crystal structure of the beta-porphyranase BpGH16B (BACPLE_01689) from the human gut bacterium Bacteroides plebeius | 分子名称: | BETA-PORPHYRANASE, CALCIUM ION, GLYCEROL | 著者 | Hehemann, J.H, Kelly, A.G, Pudlo, N.A, Martens, E.C, Boraston, A.B. | 登録日 | 2012-06-01 | 公開日 | 2012-07-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes. Proc. Natl. Acad. Sci. U.S.A., 109, 2012
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5UPI
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5V1W
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5UWN
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![BU of 5uwn by Molmil](/molmil-images/mine/5uwn) | Matrix metalloproteinase-13 complexed with selective inhibitor compound 10d | 分子名称: | CALCIUM ION, Collagenase 3, N-(2-aminoethyl)-4'-(((4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)thio)methyl)-[1,1'-biphenyl]-4-sulfonami de, ... | 著者 | Taylor, A.B, Cao, X, Hart, P.J. | 登録日 | 2017-02-21 | 公開日 | 2017-07-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors. J. Med. Chem., 60, 2017
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5UYL
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![BU of 5uyl by Molmil](/molmil-images/mine/5uyl) | 70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. | 登録日 | 2017-02-24 | 公開日 | 2017-06-14 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Ensemble cryo-EM elucidates the mechanism of translation fidelity. Nature, 546, 2017
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5UPM
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5VYH
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![BU of 5vyh by Molmil](/molmil-images/mine/5vyh) | Crystal Structure of MERS-CoV S1 N-terminal Domain | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ... | 著者 | Wang, N, Wrapp, D, Pallesen, J, Ward, A.B, McLellan, J.S. | 登録日 | 2017-05-25 | 公開日 | 2017-08-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4AK5
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![BU of 4ak5 by Molmil](/molmil-images/mine/4ak5) | Native crystal structure of BpGH117 | 分子名称: | 1,2-ETHANEDIOL, ANHYDRO-ALPHA-L-GALACTOSIDASE, CHLORIDE ION, ... | 著者 | Hehemann, J.H, Smyth, L, Yadav, A, Vocadlo, D.J, Boraston, A.B. | 登録日 | 2012-02-21 | 公開日 | 2012-03-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Analysis of Keystone Enzyme in Agar Hydrolysis Provides Insight Into the Degradation (of a Polysaccharide from) Red Seaweeds. J.Biol.Chem., 287, 2012
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4B28
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![BU of 4b28 by Molmil](/molmil-images/mine/4b28) | Crystal structure of DMSP lyase RdDddP from Roseobacter denitrificans | 分子名称: | FE (III) ION, METALLOPEPTIDASE, FAMILY M24, ... | 著者 | Hehemann, J.H, Law, A, Redecke, L, Boraston, A.B. | 登録日 | 2012-07-12 | 公開日 | 2012-07-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The Structure of Rddddp from Roseobacter Denitrificans Reveals that Dmsp Lyases in the Dddp-Family are Metalloenzymes. Plos One, 9, 2014
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4AZ6
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![BU of 4az6 by Molmil](/molmil-images/mine/4az6) | Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH | 分子名称: | 1,2-ETHANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, BETA-N-ACETYLHEXOSAMINIDASE, ... | 著者 | Pluvinage, B, Stubbs, K.A, Vocadlo, D.J, Boraston, A.B. | 登録日 | 2012-06-23 | 公開日 | 2013-07-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh. Org.Biomol.Chem., 11, 2013
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4AW7
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![BU of 4aw7 by Molmil](/molmil-images/mine/4aw7) | BpGH86A: A beta-porphyranase of glycoside hydrolase family 86 from the human gut bacterium Bacteroides plebeius | 分子名称: | 1,2-ETHANEDIOL, 6-O-sulfo-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-3,6-anhydro-alpha-L-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-6-O-sulfo-alpha-L-galactopyranose-(1-3)-alpha-D-galactopyranose, CALCIUM ION, ... | 著者 | Hehemann, J.H, Kelly, A.G, Pudlo, N.A, Martens, E.C, Boraston, A.B. | 登録日 | 2012-06-01 | 公開日 | 2012-07-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | 主引用文献 | Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes. Proc. Natl. Acad. Sci. U.S.A., 109, 2012
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5VN8
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![BU of 5vn8 by Molmil](/molmil-images/mine/5vn8) | Cryo-EM model of B41 SOSIP.664 in complex with fragment antigen binding variable domain of b12 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | 著者 | Ozorowski, G, Pallesen, J, Ward, A.B, Cottrell, C.A. | 登録日 | 2017-04-28 | 公開日 | 2017-07-12 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike. Nature, 547, 2017
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5VQZ
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![BU of 5vqz by Molmil](/molmil-images/mine/5vqz) | Crystal Structure of HIV-1 Reverse Transcriptase (K103N, Y181C) Variant in Complex with 2-chloro-N-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-N-methylacetamide (JLJ686), a Non-nucleoside Inhibitor | 分子名称: | N-(6-cyano-3-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-4-methylnaphthalen-1-yl)-N-methylacetamide, Reverse transcriptase/ribonuclease H, SULFATE ION, ... | 著者 | Buckingham, A.B, Chan, A.H, Anderson, K.S. | 登録日 | 2017-05-09 | 公開日 | 2017-08-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4AAX
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![BU of 4aax by Molmil](/molmil-images/mine/4aax) | CpGH89CBM32-5, from Clostridium perfringens, in complex with N- acetylgalactosamine | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, ALPHA-N-ACETYLGLUCOSAMINIDASE, CALCIUM ION, ... | 著者 | Ficko-Blean, E, Stuart, C.P, Suits, M.D, Cid, M, Tessier, M, Woods, R.J, Boraston, A.B. | 登録日 | 2011-12-05 | 公開日 | 2012-04-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Carbohydrate Recognition by an Architecturally Complex Alpha-N-Acetylglucosaminidase from Clostridium Perfringens. Plos One, 7, 2012
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4A34
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4A42
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![BU of 4a42 by Molmil](/molmil-images/mine/4a42) | CpGH89CBM32-6 produced by Clostridium perfringens | 分子名称: | ALPHA-N-ACETYLGLUCOSAMINIDASE FAMILY PROTEIN, CALCIUM ION | 著者 | Ficko-Blean, E, Stuart, C.P, Suits, M.D, Cid, M, Tessier, M, Woods, R.J, Boraston, A.B. | 登録日 | 2011-10-06 | 公開日 | 2012-04-04 | 最終更新日 | 2012-04-18 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Carbohydrate Recognition by an Architecturally Complex Alpha-N-Acetylglucosaminidase from Clostridium Perfringens. Plos One, 7, 2012
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5UPO
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4BFQ
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![BU of 4bfq by Molmil](/molmil-images/mine/4bfq) | Assembly of a triple pi-stack of ligands in the binding site of Aplysia californica acetylcholine binding protein (AChBP) | 分子名称: | 4,6-dimethyl-N'-(3-pyridin-2-ylisoquinolin-1-yl)pyrimidine-2-carboximidamide, GLYCEROL, SOLUBLE ACETYLCHOLINE RECEPTOR | 著者 | Stornaiuolo, M, De Kloe, G.E, Rucktooa, P, Fish, A, van Elk, R, Edink, E.S, Bertrand, D, Smit, A.B, de Esch, I.J.P, Sixma, T.K. | 登録日 | 2013-03-21 | 公開日 | 2013-05-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Assembly of a Pi-Pi Stack of Ligands in the Binding Site of an Acetylcholine Binding Protein Nat.Commun., 4, 2013
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5UWL
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![BU of 5uwl by Molmil](/molmil-images/mine/5uwl) | Matrix metalloproteinase-13 complexed with selective inhibitor compound (S)-17a | 分子名称: | (S)-N-(3-methyl-1-(methylamino)-1-oxobutan-2-yl)-5-(4-(((4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)thio)methyl)phenyl)furan-2-carboxamide, CALCIUM ION, Collagenase 3, ... | 著者 | Taylor, A.B, Cao, X, Hart, P.J. | 登録日 | 2017-02-21 | 公開日 | 2017-07-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors. J. Med. Chem., 60, 2017
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4D6G
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![BU of 4d6g by Molmil](/molmil-images/mine/4d6g) | Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the blood group A-trisaccharide (L19 mutant) | 分子名称: | 1,2-ETHANEDIOL, GLYCOSIDE HYDROLASE, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose | 著者 | Kwan, D.H, Constantinescu, I, Chapanian, R, Higgins, M.A, Samain, E, Boraston, A.B, Kizhakkedathu, J.N, Withers, S.G. | 登録日 | 2014-11-11 | 公開日 | 2014-11-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Towards Efficient Enzymes for the Generation of Universal Blood Through Structure-Guided Directed Evolution. J.Am.Chem.Soc., 137, 2015
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4D71
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![BU of 4d71 by Molmil](/molmil-images/mine/4d71) | Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 2 blood group A-tetrasaccharide (E558A X02 mutant) | 分子名称: | 1,2-ETHANEDIOL, GLYCOSIDE HYDROLASE, SULFATE ION, ... | 著者 | Kwan, D.H, Constantinescu, I, Chapanian, R, Higgins, M.A, Samain, E, Boraston, A.B, Kizhakkedathu, J.N, Withers, S.G. | 登録日 | 2014-11-19 | 公開日 | 2015-01-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Towards Efficient Enzymes for the Generation of Universal Blood Through Structure-Guided Directed Evolution. J.Am.Chem.Soc., 137, 2015
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5TA0
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![BU of 5ta0 by Molmil](/molmil-images/mine/5ta0) | Crystal structure of BuGH86E322Q in complex with neoagarooctaose | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... | 著者 | Pluvinage, B, Boraston, A.B, Abbott, W.D. | 登録日 | 2016-09-09 | 公開日 | 2017-09-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nat Commun, 9, 2018
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5T9A
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![BU of 5t9a by Molmil](/molmil-images/mine/5t9a) | Crystal structure of BuGH2Cwt | 分子名称: | 1,2-ETHANEDIOL, Glycoside Hydrolase, SULFATE ION | 著者 | Pluvinage, B, Boraston, A.B, Abbott, W.D. | 登録日 | 2016-09-09 | 公開日 | 2017-09-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nat Commun, 9, 2018
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5T7A
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![BU of 5t7a by Molmil](/molmil-images/mine/5t7a) | Crystal structure of Br derivative BhCBM56 | 分子名称: | 1,2-ETHANEDIOL, BH0236 protein, BROMIDE ION | 著者 | Pluvinage, B, Boraston, A.B. | 登録日 | 2016-09-02 | 公開日 | 2017-08-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Properties of a family 56 carbohydrate-binding module and its role in the recognition and hydrolysis of beta-1,3-glucan. J. Biol. Chem., 292, 2017
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