3HOG
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2BW7
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![BU of 2bw7 by Molmil](/molmil-images/mine/2bw7) | A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen | Descriptor: | 2,3,17BETA-TRIHYDROXY-1,3,5(10)-ESTRATRIENE, ADENYLATE CYCLASE, CALCIUM ION, ... | Authors: | Steegborn, C, Litvin, T.N, Hess, K.C, Capper, A.B, Taussig, R, Buck, J, Levin, L.R, Wu, H. | Deposit date: | 2005-07-12 | Release date: | 2005-07-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A Novel Mechanism for Adenylyl Cyclase Inhibition from the Crystal Structure of its Complex with Catechol Estrogen J.Biol.Chem., 280, 2005
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3SEY
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![BU of 3sey by Molmil](/molmil-images/mine/3sey) | Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II) | Descriptor: | ACETATE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-11 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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3SB6
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![BU of 3sb6 by Molmil](/molmil-images/mine/3sb6) | Cu-mediated Dimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization | Descriptor: | CHLORIDE ION, COPPER (II) ION, Lysozyme | Authors: | Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-03 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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2GNU
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![BU of 2gnu by Molmil](/molmil-images/mine/2gnu) | The crystallization of reaction center from Rhodobacter sphaeroides occurs via a new route | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | Authors: | Wadsten, P, Woehri, A.B, Snijder, A, Katona, G, Gardiner, A.T, Cogdell, R.J, Neutze, R, Engstroem, S. | Deposit date: | 2006-04-11 | Release date: | 2006-11-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Lipidic sponge phase crystallization of membrane proteins J.Mol.Biol., 364, 2006
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2GPP
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![BU of 2gpp by Molmil](/molmil-images/mine/2gpp) | Estrogen Related Receptor-gamma ligand binding domain complexed with a RIP140 peptide and synthetic ligand GSK4716 | Descriptor: | 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE, Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1 | Authors: | Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T. | Deposit date: | 2006-04-18 | Release date: | 2006-09-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation. J.Biol.Chem., 281, 2006
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3SEX
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![BU of 3sex by Molmil](/molmil-images/mine/3sex) | Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form II) | Descriptor: | IODIDE ION, Maltose-binding periplasmic protein, NICKEL (II) ION, ... | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-11 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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3S9L
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![BU of 3s9l by Molmil](/molmil-images/mine/3s9l) | Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | Authors: | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | Deposit date: | 2011-06-01 | Release date: | 2011-08-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH. Proc.Natl.Acad.Sci.USA, 108, 2011
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2C3X
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![BU of 2c3x by Molmil](/molmil-images/mine/2c3x) | Structure of iodinated CBM25 from Bacillus halodurans amylase in complex with maltotetraose | Descriptor: | ALPHA-AMYLASE G-6, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Boraston, A.B, Healey, M, Klassen, J, Ficko-Blean, E, Lammerts van Bueren, A, Law, V. | Deposit date: | 2005-10-12 | Release date: | 2005-10-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A Structural and Functional Analysis of Alpha-Glucan Recognition by Family 25 and 26 Carbohydrate-Binding Modules Reveals a Conserved Mode of Starch Recognition J.Biol.Chem., 281, 2006
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3V83
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![BU of 3v83 by Molmil](/molmil-images/mine/3v83) | The 2.1 angstrom crystal structure of diferric human transferrin | Descriptor: | BICARBONATE ION, FE (III) ION, HEXAETHYLENE GLYCOL, ... | Authors: | Noinaj, N, Steere, A, Mason, A.B, Buchanan, S.K. | Deposit date: | 2011-12-22 | Release date: | 2012-02-15 | Last modified: | 2012-04-18 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Structural basis for iron piracy by pathogenic Neisseria. Nature, 483, 2012
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3UPV
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![BU of 3upv by Molmil](/molmil-images/mine/3upv) | TPR2B-domain:pHsp70-complex of yeast Sti1 | Descriptor: | Heat shock protein SSA4, Heat shock protein STI1 | Authors: | Schmid, A.B, Lagleder, S, Graewert, M.A, Roehl, A, Hagn, F, Wandinger, S.K, Cox, M.B, Demmer, O, Richter, K, Groll, M, Kessler, H. | Deposit date: | 2011-11-18 | Release date: | 2012-01-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop. Embo J., 31, 2012
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3SEW
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![BU of 3sew by Molmil](/molmil-images/mine/3sew) | Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I) | Descriptor: | CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-11 | Release date: | 2011-09-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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6U54
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![BU of 6u54 by Molmil](/molmil-images/mine/6u54) | Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire C (ZC) Complexed with Zaire ebolavirus Nucleoprotein C-terminal Domain 634-739 | Descriptor: | Anti-Zaire ebolavirus Nucleoprotein Single Domain Antibody Zaire C (ZC), Nucleoprotein | Authors: | Taylor, A.B, Sherwood, L.J, Hart, P.J, Hayhurst, A. | Deposit date: | 2019-08-26 | Release date: | 2019-11-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Paratope Duality and Gullying are Among the Atypical Recognition Mechanisms Used by a Trio of Nanobodies to Differentiate Ebolavirus Nucleoproteins. J.Mol.Biol., 431, 2019
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3SBB
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![BU of 3sbb by Molmil](/molmil-images/mine/3sbb) | Disulphide-mediated Tetramer of T4 Lysozyme R76C/R80C by Synthetic Symmetrization | Descriptor: | CHLORIDE ION, Lysozyme | Authors: | Laganowsky, A, Soriaga, A.B, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. | Deposit date: | 2011-06-03 | Release date: | 2011-09-21 | Last modified: | 2015-01-28 | Method: | X-RAY DIFFRACTION (1.434 Å) | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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2BR7
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![BU of 2br7 by Molmil](/molmil-images/mine/2br7) | Crystal Structure of Acetylcholine-binding Protein (AChBP) from Aplysia californica in complex with HEPES | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SOLUBLE ACETYLCHOLINE RECEPTOR | Authors: | Celie, P.H.N, Kasheverov, I.E, Mordvintsev, D.Y, Hogg, R.C, Van Nierop, P, Van Elk, R, Van Rossum-Fikkert, S.E, Zhmak, M.N, Bertrand, D, Tsetlin, V, Sixma, T.K, Smit, A.B. | Deposit date: | 2005-05-03 | Release date: | 2005-06-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of Nicotinic Acetylcholine Receptor Homolog Achbp in Complex with an Alpha- Conotoxin Pnia Variant Nat.Struct.Mol.Biol., 12, 2005
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2BR8
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![BU of 2br8 by Molmil](/molmil-images/mine/2br8) | Crystal Structure of Acetylcholine-binding Protein (AChBP) from Aplysia californica in complex with an alpha-conotoxin PnIA variant | Descriptor: | ALPHA-CONOTOXIN PNIA, SOLUBLE ACETYLCHOLINE RECEPTOR, SULFATE ION | Authors: | Celie, P.H.N, Kasheverov, I.E, Mordvintsev, D.Y, Hogg, R.C, van Nierop, P, van Elk, R, van Rossum-Fikkert, S.E, Zhmak, M.N, Bertrand, D, Tsetlin, V, Sixma, T.K, Smit, A.B. | Deposit date: | 2005-05-03 | Release date: | 2005-06-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Nicotinic Acetylcholine Receptor Homolog Achbp in Complex with an Alpha-Conotoxin Pnia Variant Nat.Struct.Mol.Biol., 12, 2005
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3UAQ
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![BU of 3uaq by Molmil](/molmil-images/mine/3uaq) | Crystal Structure of the N-lobe Domain of Lactoferrin Binding Protein B (LbpB) of Moraxella bovis | Descriptor: | LbpB B-lobe | Authors: | Arutyunova, E, Brooks, C.L, Beddeck, A, Mak, M.W, Schryvers, A.B, Lemieux, M.J. | Deposit date: | 2011-10-21 | Release date: | 2012-03-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9318 Å) | Cite: | Crystal structure of the N-lobe of lactoferrin binding protein B from Moraxella bovis(1). Biochem.Cell Biol., 90, 2012
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3GZO
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![BU of 3gzo by Molmil](/molmil-images/mine/3gzo) | HUMAN SOD1 G93A Variant | Descriptor: | COPPER (II) ION, GLYCEROL, MALONATE ION, ... | Authors: | Galaleldeen, A, Taylor, A.B, Narayana, N, Whitson, L.J, Hart, P.J. | Deposit date: | 2009-04-07 | Release date: | 2009-10-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A. Arch.Biochem.Biophys., 492, 2009
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3H2Q
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![BU of 3h2q by Molmil](/molmil-images/mine/3h2q) | Human SOD1 H80R variant, P21 crystal form | Descriptor: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J. | Deposit date: | 2009-04-14 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding
and Compromised Post-translational Modification by the Copper Chaperone CCS To be Published
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6U02
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![BU of 6u02 by Molmil](/molmil-images/mine/6u02) | CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab-63 Heavy Chain, Fab-63 Light Chain, ... | Authors: | Ward, A.B, Turner, H.L, Zhu, X. | Deposit date: | 2019-08-13 | Release date: | 2019-12-04 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe, 26, 2019
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6UGQ
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![BU of 6ugq by Molmil](/molmil-images/mine/6ugq) | Human Carbonic Anhydrase IX-mimic complexed with SB4-206 | Descriptor: | 5-chloro-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase IX-mimic, ZINC ION | Authors: | Murray, A.B, Lomelino, C.L, McKenna, R. | Deposit date: | 2019-09-26 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.305 Å) | Cite: | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
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6U4T
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![BU of 6u4t by Molmil](/molmil-images/mine/6u4t) | Carbonic anhydrase 9 in complex with SB4197 | Descriptor: | 4-methyl-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ZINC ION | Authors: | Murray, A.B, Lomelino, C.L, McKenna, R. | Deposit date: | 2019-08-26 | Release date: | 2020-01-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.356 Å) | Cite: | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
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6U6Z
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![BU of 6u6z by Molmil](/molmil-images/mine/6u6z) | Human SAMHD1 bound to deoxyribo(TG*TTCA)-oligonucleotide | Descriptor: | DNA polymer TG(PST)TCA, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION | Authors: | Taylor, A.B, Yu, C.H, Ivanov, D.N. | Deposit date: | 2019-08-30 | Release date: | 2020-09-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification. Nat Commun, 12, 2021
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3VFI
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![BU of 3vfi by Molmil](/molmil-images/mine/3vfi) | Crystal Structure of a Metagenomic Thioredoxin | Descriptor: | thioredoxin | Authors: | Craig, T.K, Gardberg, A, Lorimer, D.D, Burgin Jr, A.B, Segall, A, Rohwer, F. | Deposit date: | 2012-01-09 | Release date: | 2013-01-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of a Metagenomic Thioredoxin To be Published
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2BJ0
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![BU of 2bj0 by Molmil](/molmil-images/mine/2bj0) | Crystal Structure of AChBP from Bulinus truncatus revals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ACETYLCHOLINE-BINDING PROTEIN | Authors: | Celie, P.H.N, Klaassen, R.V, Van Rossum-Fikkert, S.E, Van Elk, R, Van Nierop, P, Smit, A.B, Sixma, T.K. | Deposit date: | 2005-01-27 | Release date: | 2005-05-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Acetylcholine-Binding Protein from Bulinus Truncatus Reveals the Conserved Structural Scaffold and Sites of Variation in Nicotinic Acetylcholine Receptors. J.Biol.Chem., 280, 2005
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