8EH5
 
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1RZ9
 | | Crystal Structure of AAV Rep complexed with the Rep-binding sequence | | 分子名称: | 26-MER, Rep protein | | 著者 | Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M, Dyda, F. | | 登録日 | 2003-12-24 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
Mol.Cell, 13, 2004
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1RYO
 | | Human serum transferrin, N-lobe bound with oxalate | | 分子名称: | FE (III) ION, OXALATE ION, Serotransferrin | | 著者 | Halbrooks, P.J, Mason, A.B, Adams, T.E, Briggs, S.K, Everse, S.J. | | 登録日 | 2003-12-22 | | 公開日 | 2004-05-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | The oxalate effect on release of iron from human serum transferrin explained.
J.Mol.Biol., 339, 2004
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8ESC
 | | Structure of the Yeast NuA4 Histone Acetyltransferase Complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | | 著者 | Patel, A.B, Zukin, S.A, Nogales, E. | | 登録日 | 2022-10-13 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure and flexibility of the yeast NuA4 histone acetyltransferase complex.
Elife, 11, 2022
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1SI0
 | | Crystal Structure of Mannheimia haemolytica Ferric iron-Binding Protein A in a closed conformation | | 分子名称: | 1,2-ETHANEDIOL, CARBONATE ION, FE (III) ION, ... | | 著者 | Shouldice, S.R, Skene, R.J, Dougan, D.R, Snell, G, McRee, D.E, Schryvers, A.B, Tari, L.W. | | 登録日 | 2004-02-26 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structural basis for iron binding and release by a novel class of periplasmic iron-binding proteins found in gram-negative pathogens.
J.Bacteriol., 186, 2004
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1SC7
 | | Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex | | 分子名称: | 4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ... | | 著者 | Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B. | | 登録日 | 2004-02-11 | | 公開日 | 2005-04-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex
J.Med.Chem., 48, 2005
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8DZK
 | | Dbr1 in complex with 5-mer cleavage product | | 分子名称: | FE (II) ION, RNA (5'-R(P*(G46)P*UP*GP*UP*U)-3'), RNA lariat debranching enzyme, ... | | 著者 | Clark, N.E, Taylor, A.B. | | 登録日 | 2022-08-08 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the RNA Lariat Debranching Enzyme Dbr1 with Hydrolyzed Phosphorothioate RNA Product.
Biochemistry, 61, 2022
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2VAL
 | | Crystal structure of an Escherichia coli tRNAGly microhelix at 2.0 Angstrom resolution | | 分子名称: | 5'-R(*GP*CP*GP*GP*GP*AP*AP)-3', 5'-R(*UP*UP*CP*CP*CP*GP*CP)-3', MAGNESIUM ION | | 著者 | Forster, C, Brauer, A.B.E, Perbandt, M, Lehmann, D, Furste, J.P, Betzel, C, Erdmann, V.A. | | 登録日 | 2007-09-03 | | 公開日 | 2007-10-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of an Escherichia Coli Trnagly Microhelix at 2.0 Angstrom Resolution
Biochem.Biophys.Res.Commun., 363, 2007
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2V6W
 | | tRNASer acceptor stem: Conformation and hydration of a microhelix in a crystal structure at 1.8 Angstrom resolution | | 分子名称: | 5'-R(*GP*GP*AP*GP*AP*GP*AP)-3', 5'-R(*UP*CP*UP*CP*UP*CP*CP)-3' | | 著者 | Foerster, C, Brauer, A.B.E, Brode, S, Fuerste, J.P, Betzel, C, Erdmann, V.A. | | 登録日 | 2007-07-23 | | 公開日 | 2007-11-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Trnaser Acceptor Stem: Conformation and Hydration of a Microhelix in a Crystal Structure at 1.8 A Resolution.
Acta Crystallogr.,Sect.D, 63, 2007
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7JVI
 | | Crystal structure of a beta-helix domain retrieved from capybara gut metagenome | | 分子名称: | Beta-helix domain, CALCIUM ION | | 著者 | Martins, M.P, Genoroso, W.C, Domingues, M.N, Persinoti, G.F, Morais, M.A.B, Murakami, M.T. | | 登録日 | 2020-08-21 | | 公開日 | 2021-09-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides.
Nat Commun, 13, 2022
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7JVH
 | | Crystal structure of a GH43_12 retrieved from capybara gut metagenome | | 分子名称: | GLYCEROL, Glycoside Hydrolase Family 43_12 | | 著者 | Cabral, L, Domingues, M.N, Martins, M.P, Persinoti, G.F, Morais, M.A.B, Murakami, M.T. | | 登録日 | 2020-08-21 | | 公開日 | 2021-09-08 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Crystal structure of a GH43_12 retrieved from capybara gut metagenome
To Be Published
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6MS2
 | | Crystal structure of the GH43 BlXynB protein from Bacillus licheniformis | | 分子名称: | CALCIUM ION, Glycoside Hydrolase Family 43 | | 著者 | Zanphorlin, L.M, Morais, M.A.B, Diogo, J.A, Murakami, M.T. | | 登録日 | 2018-10-16 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | | 主引用文献 | Structure-guided design combined with evolutionary diversity led to the discovery of the xylose-releasing exo-xylanase activity in the glycoside hydrolase family 43.
Biotechnol. Bioeng., 116, 2019
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1SEU
 | | Human DNA Topoisomerase I (70 Kda) In Complex With The Indolocarbazole SA315F and Covalent Complex With A 22 Base Pair DNA Duplex | | 分子名称: | 2,10-DIHYDROXY-12-(BETA-D-GLUCOPYRANOSYL)-6,7,12,13-TETRAHYDROINDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE-5,7-DIONE, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', ... | | 著者 | Staker, B.L, Feese, M.D, Cushman, M, Pommier, Y, Zembower, D, Stewart, L, Burgin, A.B. | | 登録日 | 2004-02-18 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex
J.Med.Chem., 48, 2005
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8EQN
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8EJE
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8EJJ
 | | Lassa virus glycoprotein complex (Josiah) bound to S370.7 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Perrett, H.R, Ward, A.B. | | 登録日 | 2022-09-16 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
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8EJF
 | | Structure of lineage V Lassa virus glycoprotein complex (strain Soromba-R) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Perrett, H.R, Ward, A.B. | | 登録日 | 2022-09-16 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
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8EJH
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8D89
 | | Crystal structure of a novel GH5 enzyme retrieved from capybara gut metagenome | | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Martins, M.P, Morais, M.A.B, Murakami, M.T. | | 登録日 | 2022-06-08 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-beta-mannans.
Acta Crystallogr D Struct Biol, 78, 2022
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8EJI
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8EJG
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8EJD
 | | Structure of lineage IV Lassa virus glycoprotein complex (strain Josiah) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Perrett, H.R, Ward, A.B. | | 登録日 | 2022-09-16 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Cell Rep, 42, 2023
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1TK3
 | | Crystal Structure Of Human Apo Dipeptidyl Peptidase IV/CD26 | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Bjelke, J.R, Christensen, J, Branner, S, Wagtmann, N, Olsen, C, Kanstrup, A.B, Rasmussen, H.B. | | 登録日 | 2004-06-08 | | 公開日 | 2004-07-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Tyrosine 547 Constitutes an Essential Part of the Catalytic Mechanism of Dipeptidyl Peptidase IV
J.Biol.Chem., 279, 2004
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1Q0X
 | | Anti-morphine Antibody 9B1 Unliganded Form | | 分子名称: | Fab 9B1, heavy chain, light chain, ... | | 著者 | Pozharski, E, Wilson, M.A, Hewagama, A, Shanafelt, A.B, Petsko, G, Ringe, D. | | 登録日 | 2003-07-17 | | 公開日 | 2004-04-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine
J.Mol.Biol., 337, 2004
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1Q6K
 | | Cathepsin K complexed with t-butyl(1S)-1-cyclohexyl-2-oxoethylcarbamate | | 分子名称: | Cathepsin K, SULFATE ION, TERT-BUTYL(1S)-1-CYCLOHEXYL-2-OXOETHYLCARBAMATE | | 著者 | Catalano, J.G, Deaton, D.N, Furfine, E.S, Hassell, A.M, McFadyen, R.B, Miller, A.B, Miller, L.R, Shewchuk, L.M, Willard, D.H, Wright, L.L. | | 登録日 | 2003-08-13 | | 公開日 | 2004-03-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Exploration of the P1 SAR of aldehyde cathepsin K inhibitors
Bioorg.Med.Chem.Lett., 14, 2004
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