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8TFY
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BU of 8tfy by Molmil
tRNA 2'-phosphotransferase (Tpt1) from Pyrococcus horikoshii in complex with NADP
Descriptor: CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Probable RNA 2'-phosphotransferase
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2023-07-12
Release date:2023-11-08
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD.
Proc.Natl.Acad.Sci.USA, 120, 2023
8TG6
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BU of 8tg6 by Molmil
tRNA 2'-phosphotransferase (Tpt1) from Aeropyrum pernix in complex with sulfate anions
Descriptor: CHLORIDE ION, Probable RNA 2'-phosphotransferase, SULFATE ION
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2023-07-12
Release date:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for Tpt1-catalyzed 2'-PO 4 transfer from RNA and NADP(H) to NAD.
Proc.Natl.Acad.Sci.USA, 120, 2023
7KW9
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BU of 7kw9 by Molmil
NMR Structure of a tRNA 2'-phosphotransferase from Runella slithyformis in complex with NAD+
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, tRNA 2'-phosphotransferase
Authors:Alphonse, S, Dantuluri, S, Banerjee, A, Shuman, S, Ghose, R.
Deposit date:2020-11-30
Release date:2021-10-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR solution structures of Runella slithyformis RNA 2'-phosphotransferase Tpt1 provide insights into NAD+ binding and specificity.
Nucleic Acids Res., 49, 2021
7KW8
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BU of 7kw8 by Molmil
NMR Structure of a tRNA 2'-phosphotransferase from Runella slithyformis
Descriptor: tRNA 2'-phosphotransferase
Authors:Alphonse, S, Dantuluri, S, Banerjee, A, Shuman, S, Ghose, R.
Deposit date:2020-11-30
Release date:2021-10-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR solution structures of Runella slithyformis RNA 2'-phosphotransferase Tpt1 provide insights into NAD+ binding and specificity.
Nucleic Acids Res., 49, 2021
4XBA
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BU of 4xba by Molmil
Hnt3
Descriptor: Aprataxin-like protein, GLYCEROL, GUANOSINE, ...
Authors:Jacewicz, A, Chauleau, M, Shuman, S.
Deposit date:2014-12-16
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:DNA3'pp5'G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition.
Nucleic Acids Res., 43, 2015
6NVP
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BU of 6nvp by Molmil
Crystal structure of Pseudomonas putida nuclease MPE
Descriptor: MANGANESE (II) ION, Nuclease MPE
Authors:Goldgur, Y, Shuman, S, Ejaz, A.
Deposit date:2019-02-05
Release date:2019-03-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Activity and structure ofPseudomonas putidaMPE, a manganese-dependent single-strand DNA endonuclease encoded in a nucleic acid repair gene cluster.
J.Biol.Chem., 294, 2019
5COV
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BU of 5cov by Molmil
Structure and mechanism of a eukaryal nick-sealing RNA ligase K170M+Mn
Descriptor: MANGANESE (II) ION, Naegleria gruberi RNA ligase
Authors:Unciuleac, M.C, Goldgur, Y, Shuman, S.
Deposit date:2015-07-20
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase.
Proc.Natl.Acad.Sci.USA, 112, 2015
6NVO
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BU of 6nvo by Molmil
Crystal structure of Pseudomonas putida nuclease MPE
Descriptor: MANGANESE (II) ION, Nuclease MPE
Authors:Goldgur, Y, Shuman, S, Ejaz, A.
Deposit date:2019-02-05
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:Activity and structure ofPseudomonas putidaMPE, a manganese-dependent single-strand DNA endonuclease encoded in a nucleic acid repair gene cluster.
J.Biol.Chem., 294, 2019
1FVI
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BU of 1fvi by Molmil
CRYSTAL STRUCTURE OF CHLORELLA VIRUS DNA LIGASE-ADENYLATE
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORELLA VIRUS DNA LIGASE-ADENYLATE, SULFATE ION
Authors:Odell, M, Sriskanda, V, Shuman, S, Nikolov, D.B.
Deposit date:2000-09-20
Release date:2000-11-22
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of eukaryotic DNA ligase-adenylate illuminates the mechanism of nick sensing and strand joining.
Mol.Cell, 6, 2000
6O19
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BU of 6o19 by Molmil
Crystal Structure of Pho7 complex with pho1 promoter site 2
Descriptor: DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*AP*TP*TP*TP*CP*CP*GP*AP*AP*TP*AP*AP*T)-3'), DNA (5'-D(*TP*TP*AP*TP*TP*CP*GP*GP*AP*AP*AP*TP*TP*AP*AP*AP*AP*AP*CP*A)-3'), Transcription factor Pho7, ...
Authors:Garg, A, Goldgur, Y, Shuman, S.
Deposit date:2019-02-18
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.596 Å)
Cite:Structure of Fission Yeast Transcription Factor Pho7 Bound topho1Promoter DNA and Effect of Pho7 Mutations on DNA Binding and Phosphate Homeostasis.
Mol.Cell.Biol., 39, 2019
5COT
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BU of 5cot by Molmil
Structure and mechanism of a eukaryal nick-sealing RNA ligase
Descriptor: ADENOSINE MONOPHOSPHATE, Naegleria gruberi RNA ligase, UNKNOWN ATOM OR ION
Authors:Unciuleac, M.C, Goldgur, Y, Shuman, S.
Deposit date:2015-07-20
Release date:2015-10-28
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase.
Proc.Natl.Acad.Sci.USA, 112, 2015
5COU
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BU of 5cou by Molmil
Structure and mechanism of a eukaryal nick-sealing RNA ligase K170M+ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Naegleria gruberi RNA ligase
Authors:Unciuleac, M.C, Goldgur, Y, Shuman, S.
Deposit date:2015-07-20
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and two-metal mechanism of a eukaryal nick-sealing RNA ligase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YKL
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BU of 4ykl by Molmil
Hnt3 in complex with DNA and guanosine
Descriptor: Aprataxin-like protein, CHLORIDE ION, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ...
Authors:Jacewicz, A, Chauleau, M, Shuman, S.
Deposit date:2015-03-04
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:DNA3'pp5'G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition.
Nucleic Acids Res., 43, 2015
1I9S
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BU of 1i9s by Molmil
CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor: CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
1I9T
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BU of 1i9t by Molmil
CRYSTAL STRUCTURE OF THE OXIDIZED RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor: CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
5E7P
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BU of 5e7p by Molmil
Crystal Structure of MSMEG_0858 (Uniprot A0QQS4), a AAA ATPase.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein Cdc48, GLYCEROL, ...
Authors:Unciulac-Carp, M, Smith, P, Shuman, S.
Deposit date:2015-10-12
Release date:2016-08-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.507 Å)
Cite:Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase (Msm0858).
J.Bacteriol., 198, 2016
7MQW
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BU of 7mqw by Molmil
Histidine triad protein
Descriptor: HIT family protein, SULFATE ION
Authors:Ghosh, S, Goldgur, Y, Shuman, S.
Deposit date:2021-05-06
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Histidine triad protein
Unpublished
1LY1
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BU of 1ly1 by Molmil
Structure and Mechanism of T4 Polynucleotide Kinase
Descriptor: SULFATE ION, polynucleotide kinase
Authors:Wang, L.K, Lima, C.D, Shuman, S.
Deposit date:2002-06-06
Release date:2002-07-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and mechanism of T4 polynucleotide kinase: an RNA repair enzyme.
EMBO J., 21, 2002
7LD5
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BU of 7ld5 by Molmil
polynucleotide phosphorylase
Descriptor: MAGNESIUM ION, Polyribonucleotide nucleotidyltransferase, poly-A RNA fragment
Authors:Goldgur, Y, Shuman, S, De La Cruz, M.J, Ghosh, S, Unciuleac, M.-C.
Deposit date:2021-01-12
Release date:2021-06-30
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase.
Rna, 27, 2021
1RI3
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BU of 1ri3 by Molmil
Structure and mechanism of mRNA cap (guanine N-7) methyltransferase
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, mRNA CAPPING ENZYME
Authors:Fabrega, C, Hausmann, S, Shen, V, Shuman, S, Lima, C.D.
Deposit date:2003-11-16
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and mechanism of mRNA cap (Guanine-n7) methyltransferase
Mol.Cell, 13, 2004
1RI5
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BU of 1ri5 by Molmil
Structure and mechanism of mRNA cap (guanine N-7) methyltransferase
Descriptor: mRNA CAPPING ENZYME
Authors:Fabrega, C, Hausmann, S, Shen, V, Shuman, S, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2003-11-16
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and mechanism of mRNA cap (Guanine-n7) methyltransferase
Mol.Cell, 13, 2004
1RI4
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BU of 1ri4 by Molmil
Structure and mechanism of mRNA cap (guanine N-7) methyltransferase
Descriptor: S-ADENOSYLMETHIONINE, mRNA CAPPING ENZYME
Authors:Fabrega, C, Hausmann, S, Shen, V, Shuman, S, Lima, C.D.
Deposit date:2003-11-16
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and mechanism of mRNA cap (Guanine-n7) methyltransferase
Mol.Cell, 13, 2004
1RI2
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BU of 1ri2 by Molmil
Structure and mechanism of mRNA cap (guanine N-7) methyltransferase
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, mRNA CAPPING ENZYME
Authors:Fabrega, C, Hausmann, S, Shen, V, Shuman, S, Lima, C.D.
Deposit date:2003-11-16
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and mechanism of mRNA cap (Guanine-n7) methyltransferase
Mol.Cell, 13, 2004
1RI1
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BU of 1ri1 by Molmil
Structure and mechanism of mRNA cap (guanine N-7) methyltransferase
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, S-ADENOSYL-L-HOMOCYSTEINE, mRNA CAPPING ENZYME
Authors:Fabrega, C, Hausmann, S, Shen, V, Shuman, S, Lima, C.D.
Deposit date:2003-11-16
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure and mechanism of mRNA cap (Guanine-n7) methyltransferase
Mol.Cell, 13, 2004
8DCD
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BU of 8dcd by Molmil
RNA ligase RtcB from Pyrococcus horikoshii in complex with Zn2+ and GTP
Descriptor: CHLORIDE ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Jacewicz, A, Dantuluri, S, Shuman, S.
Deposit date:2022-06-16
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structures of RNA ligase RtcB in complexes with divalent cations and GTP.
Rna, 28, 2022

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