7KA0
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![BU of 7ka0 by Molmil](/molmil-images/mine/7ka0) | Crystal structure of the complex of M. tuberculosis PheRS with cognate precursor tRNA and phenylalanine | Descriptor: | ACETATE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Chang, C, Michalska, K, Jedrzejczak, R, Wower, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-09-29 | Release date: | 2021-05-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation. Nucleic Acids Res., 49, 2021
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7KAB
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![BU of 7kab by Molmil](/molmil-images/mine/7kab) | M. tuberculosis PheRS complex with cognate precursor tRNA and phenylalanine | Descriptor: | GLYCEROL, MAGNESIUM ION, PHENYLALANINE, ... | Authors: | Chang, C, Michalska, K, Jedrzejczak, R, Wower, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2020-09-30 | Release date: | 2021-05-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation. Nucleic Acids Res., 49, 2021
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6USA
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![BU of 6usa by Molmil](/molmil-images/mine/6usa) | Crystal structure of tryptophan synthase from M. tuberculosis - aminoacrylate- and GSK1-bound form | Descriptor: | (3R,4R)-4-[4-(2-Chlorophenyl)piperazin-1-yl]-1,1-dioxothiolan-3-ol, 1,2-ETHANEDIOL, 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, ... | Authors: | Chang, C, Michalska, K, Maltseva, N.I, Jedrzejczak, R, McCarren, P, Nag, P.P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-10-25 | Release date: | 2020-09-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.406 Å) | Cite: | Allosteric inhibitors of Mycobacterium tuberculosis tryptophan synthase. Protein Sci., 29, 2020
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1YQG
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![BU of 1yqg by Molmil](/molmil-images/mine/1yqg) | Crystal structure of a pyrroline-5-carboxylate reductase from neisseria meningitides mc58 | Descriptor: | SULFATE ION, pyrroline-5-carboxylate reductase | Authors: | Chang, C, Joachimiak, A, Li, H, Collart, F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-02-01 | Release date: | 2005-02-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes J.Mol.Biol., 354, 2005
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8T28
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![BU of 8t28 by Molmil](/molmil-images/mine/8t28) | The crystal structure of SrtC2 sortase from Actinomyces oris | Descriptor: | CHLORIDE ION, Class C sortase, PHOSPHATE ION | Authors: | Osipiuk, J, Chang, C, Ton-That, H.L, Ton-That, H, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | Deposit date: | 2023-06-05 | Release date: | 2024-04-17 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis for dual functions in pilus assembly modulated by the lid of a pilus-specific sortase. J.Biol.Chem., 300, 2024
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2AG8
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![BU of 2ag8 by Molmil](/molmil-images/mine/2ag8) | NADP complex of Pyrroline-5-carboxylate reductase from Neisseria meningitidis | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, pyrroline-5-carboxylate reductase | Authors: | Chang, C, Li, H, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-07-26 | Release date: | 2005-09-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes. J.Mol.Biol., 354, 2005
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2R6O
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![BU of 2r6o by Molmil](/molmil-images/mine/2r6o) | Crystal structure of putative diguanylate cyclase/phosphodiesterase from Thiobacillus denitrificans | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) | Authors: | Chang, C, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-09-06 | Release date: | 2007-09-18 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases. J.Mol.Biol., 402, 2010
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4OVM
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![BU of 4ovm by Molmil](/molmil-images/mine/4ovm) | Crystal structure of SgcJ protein from Streptomyces carzinostaticus | Descriptor: | uncharacterized protein SgcJ | Authors: | Chang, C, Bigelow, L, Clancy, S, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2013-11-20 | Release date: | 2013-12-25 | Last modified: | 2023-03-22 | Method: | X-RAY DIFFRACTION (2.719 Å) | Cite: | Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027. J.Antibiot., 2016
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4F06
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![BU of 4f06 by Molmil](/molmil-images/mine/4f06) | Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris HaA2 RPB_2270 in complex with P-HYDROXYBENZOIC ACID | Descriptor: | Extracellular ligand-binding receptor, GLYCEROL, P-HYDROXYBENZOIC ACID, ... | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-03 | Release date: | 2012-08-15 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J.Mol.Biol., 423, 2012
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4EYK
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![BU of 4eyk by Molmil](/molmil-images/mine/4eyk) | Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris BisB5 in complex with 3,4-dihydroxy benzoic acid | Descriptor: | 1,2-ETHANEDIOL, 3,4-DIHYDROXYBENZOIC ACID, Twin-arginine translocation pathway signal | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J.Mol.Biol., 423, 2012
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4EYO
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![BU of 4eyo by Molmil](/molmil-images/mine/4eyo) | Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris HaA2 in complex with p-coumaric acid | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Extracellular ligand-binding receptor | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin: p-Coumaric acid and related aromatic acids. Proteins, 81, 2013
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6BWE
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![BU of 6bwe by Molmil](/molmil-images/mine/6bwe) | Sortase A from Corynebacterium diphtheriae, lid mutant | Descriptor: | Putative fimbrial associated sortase-like protein | Authors: | Osipiuk, J, Chang, C, Huang, I.H, Ton-That, H, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-12-14 | Release date: | 2017-12-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3UKJ
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![BU of 3ukj by Molmil](/molmil-images/mine/3ukj) | Crystal structure of extracellular ligand-binding receptor from Rhodopseudomonas palustris HaA2 | Descriptor: | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, Extracellular ligand-binding receptor, GLYCEROL, ... | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-11-09 | Release date: | 2011-11-23 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin: p-Coumaric acid and related aromatic acids. Proteins, 81, 2013
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4EYG
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![BU of 4eyg by Molmil](/molmil-images/mine/4eyg) | Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris BisB5 in complex with vanillic acid | Descriptor: | 1,2-ETHANEDIOL, 4-HYDROXY-3-METHOXYBENZOATE, ISOPROPYL ALCOHOL, ... | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J.Mol.Biol., 423, 2012
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4EY3
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![BU of 4ey3 by Molmil](/molmil-images/mine/4ey3) | Crystal structure of solute binding protein of ABC transporter in complex with p-hydroxybenzoic acid | Descriptor: | P-HYDROXYBENZOIC ACID, Twin-arginine translocation pathway signal | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J.Mol.Biol., 423, 2012
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4EYQ
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![BU of 4eyq by Molmil](/molmil-images/mine/4eyq) | Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris HaA2 in complex with caffeic acid/3-(4-HYDROXY-PHENYL)PYRUVIC ACID | Descriptor: | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, CAFFEIC ACID, Extracellular ligand-binding receptor | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin: p-Coumaric acid and related aromatic acids. Proteins, 81, 2013
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1TD4
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![BU of 1td4 by Molmil](/molmil-images/mine/1td4) | Crystal structure of VSHP_BPP21 in space group H3 with high resolution. | Descriptor: | Head decoration protein | Authors: | Chang, C, Forrer, P, Ott, D, Wlodawer, A, Plueckthun, A. | Deposit date: | 2004-05-21 | Release date: | 2004-11-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Kinetic Stability and Crystal Structure of the Viral Capsid Protein SHP. J.Mol.Biol., 344, 2004
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1TD0
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![BU of 1td0 by Molmil](/molmil-images/mine/1td0) | Viral capsid protein SHP at pH 5.5 | Descriptor: | Head decoration protein | Authors: | Chang, C, Forrer, P, Ott, D, Wlodawer, A, Plueckthun, A. | Deposit date: | 2004-05-21 | Release date: | 2004-11-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Kinetic Stability and Crystal Structure of the Viral Capsid Protein SHP J.Mol.Biol., 344, 2004
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1TD3
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![BU of 1td3 by Molmil](/molmil-images/mine/1td3) | Crystal structure of VSHP_BPP21 in space group C2 | Descriptor: | Head decoration protein | Authors: | Chang, C, Forrer, P, Ott, D, Wlodawer, A, Plueckthun, A. | Deposit date: | 2004-05-21 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Kinetic Stability and Crystal Structure of the Viral Capsid Protein SHP. J.Mol.Biol., 344, 2004
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1U60
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![BU of 1u60 by Molmil](/molmil-images/mine/1u60) | MCSG APC5046 Probable glutaminase ybaS | Descriptor: | 1,2-ETHANEDIOL, FORMIC ACID, Probable glutaminase ybaS | Authors: | Chang, C, Cuff, M.E, Joachimiak, A, Savchenko, A, Edwards, A, Skarina, T, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-07-28 | Release date: | 2004-09-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis. Biochemistry, 47, 2008
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2LJK
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![BU of 2ljk by Molmil](/molmil-images/mine/2ljk) | |
5SUJ
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![BU of 5suj by Molmil](/molmil-images/mine/5suj) | Crystal structure of uncharacterized protein LPG2148 from Legionella pneumophila | Descriptor: | Uncharacterized protein | Authors: | Chang, C, Xu, X, Cui, H, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2016-08-03 | Release date: | 2016-08-17 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.356 Å) | Cite: | Discovery of Ubiquitin Deamidases in the Pathogenic Arsenal of Legionella pneumophila. Cell Rep, 23, 2018
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4Y7B
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![BU of 4y7b by Molmil](/molmil-images/mine/4y7b) | Factor Xa complex with GTC000441 | Descriptor: | 6-chloro-N-{(3S)-1-[(2S)-1-{(1R,5S)-7-[2-(methylamino)ethyl]-3,7-diazabicyclo[3.3.1]non-3-yl}-1-oxopropan-2-yl]-2-oxopy rrolidin-3-yl}naphthalene-2-sulfonamide, CALCIUM ION, Coagulation factor X | Authors: | Convery, M.A, Young, R.J, Senger, S, Hamblin, J.N, Chan, C, Toomey, J.R, Watson, N.S. | Deposit date: | 2015-02-13 | Release date: | 2015-09-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Factor Xa complex with GTC000441 to be published
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4Y7A
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![BU of 4y7a by Molmil](/molmil-images/mine/4y7a) | Factor Xa complex with GTC000422 | Descriptor: | CALCIUM ION, Coagulation factor X, MAGNESIUM ION, ... | Authors: | Convery, M.A, Young, R.J, Senger, S, Hamblin, J.N, Chan, C, Toomey, J.R, Watson, N.S. | Deposit date: | 2015-02-13 | Release date: | 2015-09-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Factor Xa complex with GTC000422 to be published
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2J38
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![BU of 2j38 by Molmil](/molmil-images/mine/2j38) | CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | Descriptor: | 5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | Authors: | Senger, S, Convery, M.A, Chan, C, Watson, N.S. | Deposit date: | 2006-08-18 | Release date: | 2006-09-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Arylsulfonamides: A Study of the Relationship between Activity and Conformational Preferences for a Series of Factor Xa Inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
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