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5VAY
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BU of 5vay by Molmil
Bcl-2 complex with Beclin 1 T108D BH3 domain
Descriptor: Apoptosis regulator Bcl-2 -- Bcl-2-like protein 1 Chimera, Beclin-1
Authors:Lee, E.F, Smith, B.J, Yao, S, Fairlie, W.D.
Deposit date:2017-03-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.804 Å)
Cite:Bcl-2 complex with Beclin 1 pT108 BH3 domain
To Be Published
5VAU
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BU of 5vau by Molmil
Bcl-2 complex with Beclin 1 BH3 domain
Descriptor: Apoptosis regulator Bcl-2 -- Bcl-2-like protein 1 Chimera, Beclin-1
Authors:Lee, E.F, Smith, B.J, Yao, S, Fairlie, W.D.
Deposit date:2017-03-28
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:Bcl-2 complex with Beclin 1 BH3 domain
To Be Published
2X6A
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BU of 2x6a by Molmil
Potassium Channel from Magnetospirillum Magnetotacticum
Descriptor: ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, PHOSPHOCHOLINE, POTASSIUM ION
Authors:Clarke, O.B, Caputo, A.T, Hill, A.P, Vandenberg, J.I, Smith, B.J, Gulbis, J.M.
Deposit date:2010-02-15
Release date:2010-06-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2X6B
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BU of 2x6b by Molmil
Potassium Channel from Magnetospirillum Magnetotacticum
Descriptor: ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, BARIUM ION, PHOSPHOCHOLINE, ...
Authors:Clarke, O.B, Caputo, A.T, Hill, A.P, Vandenberg, J.I, Smith, B.J, Gulbis, J.M.
Deposit date:2010-02-15
Release date:2010-06-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2WLN
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BU of 2wln by Molmil
POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM
Descriptor: POTASSIUM CHANNEL, POTASSIUM ION
Authors:Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.44 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2WLI
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BU of 2wli by Molmil
POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM
Descriptor: KIRBAC3.1 POTASSIUM CHANNEL, POTASSIUM CHANNEL, POTASSIUM ION
Authors:Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2WLO
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BU of 2wlo by Molmil
POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM
Descriptor: POTASSIUM CHANNEL, POTASSIUM ION
Authors:Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (4.036 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2WLM
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BU of 2wlm by Molmil
POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM
Descriptor: POTASSIUM CHANNEL, POTASSIUM ION
Authors:Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.61 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2WLL
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BU of 2wll by Molmil
POTASSIUM CHANNEL FROM BURKHOLDERIA PSEUDOMALLEI
Descriptor: DIUNDECYL PHOSPHATIDYL CHOLINE, MAGNESIUM ION, POTASSIUM CHANNEL, ...
Authors:Clarke, O.B, Caputo, A.T, Hill, A.P, VandenBerg, J.I, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2X6C
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BU of 2x6c by Molmil
Potassium Channel from Magnetospirillum Magnetotacticum
Descriptor: ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10, CHLORIDE ION, PHOSPHOCHOLINE, ...
Authors:Clarke, O.B, Caputo, A.T, Hill, A.P, Vandenberg, J.I, Smith, B.J, Gulbis, J.M.
Deposit date:2010-02-15
Release date:2010-06-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
2WLH
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BU of 2wlh by Molmil
POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM
Descriptor: CHLORIDE ION, POTASSIUM CHANNEL, POTASSIUM ION
Authors:Clarke, O.B, Caputo, A.T, Smith, B.J, Gulbis, J.M.
Deposit date:2009-06-24
Release date:2010-06-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels.
Cell(Cambridge,Mass.), 141, 2010
5WBT
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BU of 5wbt by Molmil
Solution Structure and Dynamics of an Ultra-Stable Single-Chain Insulin Analog STUDIES OF AN ENGINEERED MONOMER AND IMPLICATIONS FOR RECEPTOR BINDING
Descriptor: Insulin
Authors:Glidden, M.D, Yang, Y, Wickramasinghe, N.P, Weiss, M.A.
Deposit date:2017-06-29
Release date:2017-11-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding.
J. Biol. Chem., 293, 2018
4P65
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BU of 4p65 by Molmil
Crystal structure of an cyclohexylalanine substituted insulin analog.
Descriptor: CHLORIDE ION, Insulin, PHENOL, ...
Authors:Pandyarajan, V, Wan, Z, Weiss, M.A.
Deposit date:2014-03-21
Release date:2014-10-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Aromatic Anchor at an Invariant Hormone-Receptor Interface: FUNCTION OF INSULIN RESIDUE B24 WITH APPLICATION TO PROTEIN DESIGN.
J.Biol.Chem., 289, 2014
6W3R
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BU of 6w3r by Molmil
Crystal structure of ligand-binding domain of Campylobacter jejuni chemoreceptor Tlp3 in complex with 3-methylisoleucine
Descriptor: 3-methyl-L-alloisoleucine, CHLORIDE ION, Methyl-accepting chemotaxis protein, ...
Authors:Khan, M.F, Machuca, M.A, Rahman, M.M, Roujeinikova, A.
Deposit date:2020-03-09
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Structure-Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by theCampylobacter jejuniChemoreceptor Tlp3.
Biomolecules, 10, 2020
4WAT
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BU of 4wat by Molmil
Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IMIDAZOLE, PfRh5
Authors:Chen, L.
Deposit date:2014-09-01
Release date:2014-10-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes.
Elife, 3, 2014
6W3Y
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BU of 6w3y by Molmil
Crystal structure of ligand-binding domain of Campylobacter jejuni chemoreceptor Tlp3 in complex with L-alanine
Descriptor: ALANINE, CHLORIDE ION, GLYCEROL, ...
Authors:Khan, M.F, Machuca, M.A, Rahman, M.M, Roujeinikova, A.
Deposit date:2020-03-09
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Structure-Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by theCampylobacter jejuniChemoreceptor Tlp3.
Biomolecules, 10, 2020
6W3O
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BU of 6w3o by Molmil
Crystal structure of ligand-binding domain of Campylobacter jejuni chemoreceptor Tlp3 in complex with 4-methylisoleucine
Descriptor: 4-methylisoleucine, CHLORIDE ION, Methyl-accepting chemotaxis protein, ...
Authors:Khan, M.F, Machuca, M.A, Rahman, M.M, Roujeinikova, A.
Deposit date:2020-03-09
Release date:2020-05-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Structure-Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by theCampylobacter jejuniChemoreceptor Tlp3.
Biomolecules, 10, 2020
6W3S
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BU of 6w3s by Molmil
Crystal structure of ligand-binding domain of Campylobacter jejuni chemoreceptor Tlp3 in complex with L-leucine
Descriptor: GLYCEROL, LEUCINE, Methyl-accepting chemotaxis protein, ...
Authors:Khan, M.F, Machuca, M.A, Rahman, M.M, Roujeinikova, A.
Deposit date:2020-03-09
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure-Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by theCampylobacter jejuniChemoreceptor Tlp3.
Biomolecules, 10, 2020
7KD6
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BU of 7kd6 by Molmil
Insulin Receptor L1-CR plus alphaCT fragment in co-complex with Fv 83-7 and single-chain insulin SCI-b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lawrence, M.C, Menting, J.G.
Deposit date:2020-10-08
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Single-chain insulin analogs threaded by the insulin receptor alpha CT domain.
Biophys.J., 2022
2TMP
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BU of 2tmp by Molmil
N-TERMINAL DOMAIN OF TISSUE INHIBITOR OF METALLOPROTEINASE-2 (N-TIMP-2), NMR, 49 STRUCTURES
Descriptor: TISSUE INHIBITOR OF METALLOPROTEINASES-2
Authors:Muskett, F.W, Frenkiel, T.A, Feeney, J, Freedman, R.B, Carr, M.D, Williamson, R.A.
Deposit date:1998-05-26
Release date:1998-12-09
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3.
J.Biol.Chem., 273, 1998
4QVX
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BU of 4qvx by Molmil
Discovery of a Potent and Selective BCL-XL Inhibitor That Demonstrates Thrombocytopenia and Inhibits Tumor Growth in Vivo
Descriptor: 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-5-(3-{4-[3-(dimethylamino)prop-1-yn-1-yl]-2-fluorophenoxy}propyl)-1,3-thiazole-4-carboxylic acid, Bcl-2-like protein 1
Authors:Park, C.H.
Deposit date:2014-07-16
Release date:2015-07-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity.
ACS MED.CHEM.LETT., 5, 2014
5JYQ
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BU of 5jyq by Molmil
Structure of Conus Geographus insulin G1
Descriptor: Insulin 1, Insulin 1b, SULFATE ION
Authors:Lawrence, M.C, Menting, J, Norton, R.S, Safavi-Hemami, H.
Deposit date:2016-05-15
Release date:2016-09-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
Nat.Struct.Mol.Biol., 23, 2016
5J3H
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BU of 5j3h by Molmil
Human insulin receptor domains L1-CR in complex with peptide S519C16 and 83-7 Fv
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lawrence, M, Menting, J, Lawrence, C.
Deposit date:2016-03-30
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Insulin Mimetic Peptide Disrupts the Primary Binding Site of the Insulin Receptor.
J.Biol.Chem., 291, 2016
6MTU
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BU of 6mtu by Molmil
Crystal structure of human Scribble PDZ1:pMCC complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Colorectal mutant cancer protein, ...
Authors:Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M.
Deposit date:2018-10-22
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains.
Febs J., 286, 2019
6MTV
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BU of 6mtv by Molmil
Crystal structure of human Scribble PDZ1:MCC complex
Descriptor: Colorectal mutant cancer protein, DI(HYDROXYETHYL)ETHER, Protein scribble homolog, ...
Authors:Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M.
Deposit date:2018-10-22
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.597 Å)
Cite:Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains.
Febs J., 286, 2019

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數據於2024-09-25公開中

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