6R7R
| Crystal structure of the glutamate transporter homologue GltTk in complex with D-aspartate | Descriptor: | D-ASPARTIC ACID, DECYL-BETA-D-MALTOPYRANOSIDE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Arkhipova, V, Guskov, A, Slotboom, D.J. | Deposit date: | 2019-03-29 | Release date: | 2019-04-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Binding and transport of D-aspartate by the glutamate transporter homolog Glt Tk . Elife, 8, 2019
|
|
6RVY
| |
4MHW
| Crystal structure of ThiT with small molecule BAT-25 | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 2-{4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl}ethanol, ... | Authors: | Swier, L.J.Y.M, Guskov, A, Slotboom, D.J. | Deposit date: | 2013-08-30 | Release date: | 2014-09-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of ThiT with small molecules modulators To be Published
|
|
4MUU
| Structure of ThiT with pyrithiamine bound | Descriptor: | 1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-(2-HYDROXYETHYL)-2-METHYLPYRIDINIUM, 2-(2-METHOXYETHOXY)ETHANOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... | Authors: | Swier, L.J.Y.M, Guskov, A, Slotboom, D.J. | Deposit date: | 2013-09-23 | Release date: | 2014-09-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural studies on the thiamin binding protein ThiT To be Published
|
|
4LA9
| Crystal structure of an empty substrate binding domain 1 (SBD1) OF ABC TRANSPORTER GLNPQ from lactococcus lactis | Descriptor: | DI(HYDROXYETHYL)ETHER, Glutamine ABC transporter permease and substrate binding protein protein, PHOSPHATE ION | Authors: | Guskov, A, Schuurman-Wolters, G.K, Slotboom, D.J, Poolman, B. | Deposit date: | 2013-06-19 | Release date: | 2013-09-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria. Structure, 21, 2013
|
|
4KY0
| Crystal structure of a substrate-free glutamate transporter homologue from Thermococcus kodakarensis | Descriptor: | Proton/glutamate symporter, SDF family, TETRAETHYLENE GLYCOL | Authors: | Guskov, A, Jensen, S, Rempel, S, Hanelt, I, Slotboom, D.J. | Deposit date: | 2013-05-28 | Release date: | 2013-09-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of a substrate-free aspartate transporter. Nat.Struct.Mol.Biol., 20, 2013
|
|
4N4D
| Structure of ThiT with AV-38 bound | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, ... | Authors: | Swier, L.J.Y.M, Guskov, A, Slotboom, D.J. | Deposit date: | 2013-10-08 | Release date: | 2014-09-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural studies on the thiamine binding protein ThiT To be Published
|
|
4MES
| |
3RYB
| Lactococcal OppA complexed with SLSQSLSQS | Descriptor: | Oligopeptide, Oligopeptide-binding protein oppA | Authors: | Berntsson, R.P.-A, Thunnissen, A.-M.W.H, Poolman, B, Slotboom, D.-J. | Deposit date: | 2011-05-11 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Importance of a Hydrophobic Pocket for Peptide Binding in Lactococcal OppA. J.Bacteriol., 193, 2011
|
|
3RYA
| Lactococcal OppA complexed with SLSQLSSQS | Descriptor: | Oligopeptide, Oligopeptide-binding protein oppA | Authors: | Berntsson, R.P.-A, Thunnissen, A.-M.W.H, Poolman, B, Slotboom, D.-J. | Deposit date: | 2011-05-11 | Release date: | 2011-06-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Importance of a Hydrophobic Pocket for Peptide Binding in Lactococcal OppA. J.Bacteriol., 193, 2011
|
|
8AFA
| |
4G4P
| Crystal structure of glutamine-binding protein from Enterococcus faecalis at 1.5 A | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Amino acid ABC transporter, amino acid-binding/permease protein, ... | Authors: | Fulyani, F, Guskov, A, Zagar, A.V, Slotboom, D.-J, Poolman, B. | Deposit date: | 2012-07-16 | Release date: | 2013-07-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Functional Diversity of Tandem Substrate-Binding Domains in ABC Transporters from Pathogenic Bacteria. Structure, 21, 2013
|
|
6SGF
| Molecular insight into a new low affinity xylan binding module CBM86, from the xylanolytic gut symbiont Roseburia intestinalis. | Descriptor: | Beta-xylanase, CADMIUM ION, CHLORIDE ION, ... | Authors: | Ejby, M, Abou Hachem, M, Leth, M.L, Guskov, A, Slotboom, D. | Deposit date: | 2019-08-04 | Release date: | 2019-11-20 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.756 Å) | Cite: | Molecular insight into a new low-affinity xylan binding module from the xylanolytic gut symbiont Roseburia intestinalis. Febs J., 287, 2020
|
|
3FTO
| Crystal structure of OppA in a open conformation | Descriptor: | Oligopeptide-binding protein oppA | Authors: | Berntsson, R.P.-A, Oktaviani, N.A, Fusetti, F, Thunnissen, A.-M.W.H, Poolman, B, Slotboom, D.-J. | Deposit date: | 2009-01-13 | Release date: | 2009-03-31 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Selenomethionine incorporation in proteins expressed in Lactococcus lactis. Protein Sci., 18, 2009
|
|
7Q10
| Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B | Descriptor: | 3N methyl nemycin B, ACETATE ION, Aminoglycoside N(3)-acetyltransferase III, ... | Authors: | Pontillo, N, Guskov, A. | Deposit date: | 2021-10-17 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | 3-N-alkylation in aminoglycoside antibiotic neomycin B overcomes bacterial resistance mediated by acetyltransferase (3) IIIa To Be Published
|
|
7Q1D
| Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aminoglycoside N(3)-acetyltransferase III, CHLORIDE ION, ... | Authors: | Pontillo, N, Guskov, A. | Deposit date: | 2021-10-18 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | 3-N-alkylation in aminoglycoside antibiotic neomycin B overcomes bacterial resistance mediated by acetyltransferase (3) IIIa To Be Published
|
|
7Q1X
| Acetyltrasferase(3) type IIIa in complex with neomycin B | Descriptor: | Aminoglycoside N(3)-acetyltransferase III, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Pontillo, N, Guskov, A. | Deposit date: | 2021-10-21 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism To Be Published
|
|
7Q0Q
| Acetyltrasferase(3) type IIIa in complex with 3-N-methyl-nemycin B | Descriptor: | 3N methyl nemycin B, ACETATE ION, Aminoglycoside N(3)-acetyltransferase III, ... | Authors: | Pontillo, N, Guskov, A. | Deposit date: | 2021-10-16 | Release date: | 2022-11-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | The 3-N-alkylation of the neomycin B outmaneuvers the aminoglycoside resistant enzyme acetyltransferase(3)IIIa via an unexpected mechanism To Be Published
|
|
8PUJ
| The surface-exposed lipo-protein of BtuG2 in complex with cyanocobalamin. | Descriptor: | COB(II)INAMIDE, HYDROXIDE ION, SODIUM ION, ... | Authors: | Whittaker, J, Martinez-Felices, J.M, Guskov, A, Slotboom, D.J. | Deposit date: | 2023-07-17 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The surface-exposed lipo-protein of BtuG3 in complex with cyanocobinamide. To Be Published
|
|
8PTF
| The surface-exposed lipo-protein of BtuG2 in complex with cyanocobalamin. | Descriptor: | COB(II)INAMIDE, SODIUM ION, YncE family protein, ... | Authors: | Whittaker, J, Felices Martinez, J.M, Guskov, A, Slotboom, D.J. | Deposit date: | 2023-07-14 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The surface-exposed lipo-protein of BtuG1 in complex with cyanocobinamide. To Be Published
|
|
8PTD
| The surface-exposed lipo-protein of BtuG1 in complex with cyanocobalamin. | Descriptor: | COBALAMIN, GLYCEROL, HYDROXIDE ION, ... | Authors: | Whittaker, J, Felices Martinez, J.M, Guskov, A, Slotboom, D.J. | Deposit date: | 2023-07-14 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The surface-exposed lipo-protein of BtuG1 in complex with cyanocobalamin. To Be Published
|
|
8BAI
| The surface-exposed lipo-protein of BtuG2 in complex with cyanocobalamin. | Descriptor: | CYANOCOBALAMIN, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Whittaker, J, Martinez Felices, J.M, Guskov, A, Slotboom, D.J. | Deposit date: | 2022-10-11 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | The surface-exposed lipo-protein of BtuG2 in complex with cyanocobalamin. To Be Published
|
|
8BB0
| The surface-exposed lipo-protein of BtuG2 in complex with hydroxycobalamin. | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Whittaker, J, Felices Martinez, J.M, Guskov, A, Slotboom, D.J. | Deposit date: | 2022-10-12 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The surface-exposed lipo-protein of BtuG2 in complex with hydroxycobinamide. To Be Published
|
|
8BAZ
| The surface-exposed lipo-protein of BtuG2 in complex with cyanocobalamin. | Descriptor: | COB(II)INAMIDE, CYANIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Whittaker, J, Martinez-Felices, J.M, Guskov, A, Slotboom, D.J. | Deposit date: | 2022-10-12 | Release date: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The surface-exposed lipo-protein of BtuG2 in complex with cyanocobinamide. To Be Published
|
|