1NHU
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![BU of 1nhu by Molmil](/molmil-images/mine/1nhu) | Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor | Descriptor: | (2S)-2-[(2,4-DICHLORO-BENZOYL)-(3-TRIFLUOROMETHYL-BENZYL)-AMINO]-3-PHENYL-PROPIONIC ACID, HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE | Authors: | Wang, M, Ng, K.K.S, Cherney, M.M, Chan, L, Yannopoulos, C.G, Bedard, J, Morin, N, Nguyen-Ba, N, Alaoui-Ismaili, M.H, Bethell, R.C, James, M.N.G. | Deposit date: | 2002-12-19 | Release date: | 2003-03-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Non-Nucleoside Analogue Inhibitors Bind to an Allosteric Site on
HCV NS5B Polymerase: Crystal Structures and Mechanism of Inhibition J.Biol.Chem., 278, 2003
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2FXZ
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![BU of 2fxz by Molmil](/molmil-images/mine/2fxz) | |
1NHV
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![BU of 1nhv by Molmil](/molmil-images/mine/1nhv) | Hepatitis C virus RNA polymerase in complex with non-nucleoside analogue inhibitor | Descriptor: | (2S)-2-[(5-BENZOFURAN-2-YL-THIOPHEN-2-YLMETHYL)-(2,4-DICHLORO-BENZOYL)-AMINO]-3-PHENYL-PROPIONIC ACID, HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE | Authors: | Wang, M, Ng, K.K.S, Cherney, M.M, Chan, L, Yannopoulos, C.G, Bedard, J, Morin, N, Nguyen-Ba, N, Alaoui-Ismaili, M.H, Bethell, R.C, James, M.N.G. | Deposit date: | 2002-12-19 | Release date: | 2003-03-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Non-Nucleoside Analogue Inhibitors Bind to an Allosteric Site on
HCV NS5B Polymerase: Crystal Structures and Mechanism of Inhibition J.Biol.Chem., 278, 2003
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4X1B
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![BU of 4x1b by Molmil](/molmil-images/mine/4x1b) | Human serum transferrin with ferric ion bound at the C-lobe only | Descriptor: | FE (III) ION, GLYCEROL, MALONATE ION, ... | Authors: | Wang, M, Zhang, H, Sun, H. | Deposit date: | 2014-11-24 | Release date: | 2015-04-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | "Anion clamp" allows flexible protein to impose coordination geometry on metal ions Chem.Commun.(Camb.), 51, 2015
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4QY0
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![BU of 4qy0 by Molmil](/molmil-images/mine/4qy0) | Structure of H10 from human-infecting H10N8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | Authors: | Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F. | Deposit date: | 2014-07-23 | Release date: | 2015-01-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus Nat Commun, 6, 2015
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5ZQY
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![BU of 5zqy by Molmil](/molmil-images/mine/5zqy) | Crystal structure of a poly(ADP-ribose) glycohydrolase | Descriptor: | MAGNESIUM ION, Poly(ADP-ribose) glycohydrolase ARH3, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | Authors: | Wang, M, Yuan, Z, Ma, Y, Wang, J, Liu, X. | Deposit date: | 2018-04-20 | Release date: | 2018-08-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.577 Å) | Cite: | Structure-function analyses reveal the mechanism of the ARH3-dependent hydrolysis of ADP-ribosylation. J. Biol. Chem., 293, 2018
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1AMO
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![BU of 1amo by Molmil](/molmil-images/mine/1amo) | THREE-DIMENSIONAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE: PROTOTYPE FOR FMN-AND FAD-CONTAINING ENZYMES | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Wang, M, Roberts, D.L, Paschke, R, Shea, T.M, Masters, B.S.S, Kim, J.J.P. | Deposit date: | 1997-06-17 | Release date: | 1998-06-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes. Proc.Natl.Acad.Sci.USA, 94, 1997
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6JAS
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![BU of 6jas by Molmil](/molmil-images/mine/6jas) | Human serum transferrin with iron citrate bound | Descriptor: | CITRIC ACID, FE (III) ION, MALONATE ION, ... | Authors: | Wang, M, Wang, H, Sun, H. | Deposit date: | 2019-01-25 | Release date: | 2020-01-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Binding of ruthenium and osmium at non-iron sites of transferrin explains their iron-independent cellular uptake To Be Published
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2F48
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![BU of 2f48 by Molmil](/molmil-images/mine/2f48) | |
6IDK
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![BU of 6idk by Molmil](/molmil-images/mine/6idk) | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class I particle) | Descriptor: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | Authors: | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2018-09-10 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (25 Å) | Cite: | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure, 27, 2019
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6IDI
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![BU of 6idi by Molmil](/molmil-images/mine/6idi) | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 8.0. | Descriptor: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | Authors: | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2018-09-10 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure, 27, 2019
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7FFM
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![BU of 7ffm by Molmil](/molmil-images/mine/7ffm) | Human serum transferrin with five osmium binding sites | Descriptor: | MALONATE ION, NITRILOTRIACETIC ACID, OSMIUM ION, ... | Authors: | Wang, M, Sun, H. | Deposit date: | 2021-07-23 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake. J.Inorg.Biochem., 234, 2022
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7FFU
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![BU of 7ffu by Molmil](/molmil-images/mine/7ffu) | Osmium-bound human serum transferrin | Descriptor: | FE (III) ION, MALONATE ION, OSMIUM ION, ... | Authors: | Wang, M, Sun, H. | Deposit date: | 2021-07-23 | Release date: | 2022-06-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake. J.Inorg.Biochem., 234, 2022
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2KJ4
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![BU of 2kj4 by Molmil](/molmil-images/mine/2kj4) | Solution structure of the complex of VEK-30 and plasminogen kringle 2 | Descriptor: | VEK-30, plasminogen | Authors: | Wang, M, Zajicek, J, Prorok, M, Castellin, F.J. | Deposit date: | 2009-05-21 | Release date: | 2009-10-20 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of the complex of VEK-30 and plasminogen kringle 2. J.Struct.Biol., 169, 2010
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6IDL
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![BU of 6idl by Molmil](/molmil-images/mine/6idl) | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class II particle) | Descriptor: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | Authors: | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | Deposit date: | 2018-09-10 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (25 Å) | Cite: | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure, 27, 2019
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2KQ3
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![BU of 2kq3 by Molmil](/molmil-images/mine/2kq3) | Solution structure of SNase140 | Descriptor: | Thermonuclease | Authors: | Wang, M, Feng, Y, Yao, H, Wang, J. | Deposit date: | 2009-10-26 | Release date: | 2010-05-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Importance of the C-Terminal Loop L137-S141 for the Folding and Folding Stability of Staphylococcal Nuclease Biochemistry, 49, 2010
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7WC2
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![BU of 7wc2 by Molmil](/molmil-images/mine/7wc2) | Cryo-EM structure of alphavirus, Getah virus | Descriptor: | Spike glycoprotein E1, Spike glycoprotein E2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Wang, M, Sun, Z.Z, Wang, J.F. | Deposit date: | 2021-12-18 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Implications for the pathogenicity and antigenicity of alpha viruses revealed by a 3.5 angstrom Cryo-EM structure of Getah virus To Be Published
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7WCO
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![BU of 7wco by Molmil](/molmil-images/mine/7wco) | Cryo-EM structure of alphavirus, Getah virus | Descriptor: | Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2 | Authors: | Wang, M, Sun, Z.Z, Wang, J.F. | Deposit date: | 2021-12-20 | Release date: | 2022-11-02 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Implications for the pathogenicity and antigenicity of alpha viruses revealed by a 3.5 angstrom Cryo-EM structure of Getah virus To Be Published
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7VGA
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![BU of 7vga by Molmil](/molmil-images/mine/7vga) | Cryo-EM structure of alphavirus, Getah virus | Descriptor: | Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2 | Authors: | Wang, M, Sun, Z.Z, Wang, J.F. | Deposit date: | 2021-09-15 | Release date: | 2022-11-02 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Implications for the pathogenicity and antigenicity of alpha viruses revealed by a 3.5 angstrom Cryo-EM structure of Getah virus To Be Published
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5X5P
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![BU of 5x5p by Molmil](/molmil-images/mine/5x5p) | Human serum transferrin bound to ruthenium NTA | Descriptor: | FE (III) ION, MALONATE ION, NITRILOTRIACETIC ACID, ... | Authors: | Sun, H, Wang, M. | Deposit date: | 2017-02-17 | Release date: | 2018-02-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Binding of ruthenium and osmium at non‐iron sites of transferrin accounts for their iron-independent cellular uptake. J.Inorg.Biochem., 234, 2022
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7YTW
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![BU of 7ytw by Molmil](/molmil-images/mine/7ytw) | Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter | Descriptor: | ASCORBIC ACID, SODIUM ION, Solute carrier family 23 member 1 | Authors: | She, J, Wang, M, He, J, Zhang, K, Li, S. | Deposit date: | 2022-08-16 | Release date: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter. Nat Commun, 14, 2023
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7YTY
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![BU of 7yty by Molmil](/molmil-images/mine/7yty) | Mouse SVCT1 in an apo state | Descriptor: | Solute carrier family 23 member 1 | Authors: | She, J, Wang, M, He, J, Zhang, K, Li, S. | Deposit date: | 2022-08-16 | Release date: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter. Nat Commun, 14, 2023
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5ERG
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![BU of 5erg by Molmil](/molmil-images/mine/5erg) | Crystal structure of the two-subunit tRNA m1A58 methyltransferase TRM6-TRM61 in complex with SAM | Descriptor: | S-ADENOSYLMETHIONINE, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 | Authors: | Zhu, Y, Wang, M, Wang, C, Fan, X, Jiang, X, Teng, M, Li, X. | Deposit date: | 2015-11-14 | Release date: | 2016-09-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae. Sci Rep, 6, 2016
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5EQJ
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![BU of 5eqj by Molmil](/molmil-images/mine/5eqj) | Crystal structure of the two-subunit tRNA m1A58 methyltransferase from Saccharomyces cerevisiae | Descriptor: | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 | Authors: | Zhu, Y, Wang, M, Wang, C, Fan, X, Jiang, X, Teng, M, Li, X. | Deposit date: | 2015-11-13 | Release date: | 2016-09-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae. Sci Rep, 6, 2016
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2PL5
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![BU of 2pl5 by Molmil](/molmil-images/mine/2pl5) | Crystal Structure of Homoserine O-acetyltransferase from Leptospira interrogans | Descriptor: | GLYCEROL, Homoserine O-acetyltransferase | Authors: | Liu, L, Wang, M, Wang, Y, Wei, Z, Xu, H, Gong, W. | Deposit date: | 2007-04-19 | Release date: | 2007-11-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of homoserine O-acetyltransferase from Leptospira interrogans Biochem.Biophys.Res.Commun., 363, 2007
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