8UKH
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4YFS
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4ZEV
| Crystal structure of PfHAD1 in complex with mannose-6-phosphate | Descriptor: | 6-O-phosphono-alpha-D-mannopyranose, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Park, J, Tolia, N.H. | Deposit date: | 2015-04-20 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4ZEX
| Crystal structure of PfHAD1 in complex with glyceraldehyde-3-phosphate | Descriptor: | GLYCERALDEHYDE-3-PHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Park, J, Tolia, N.H. | Deposit date: | 2015-04-20 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4ZEW
| Crystal structure of PfHAD1 in complex with glucose-6-phosphate | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Park, J, Tolia, N.H. | Deposit date: | 2015-04-20 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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1Z26
| Structure of Pyrococcus furiosus Argonaute with bound tungstate | Descriptor: | Argonaute, TUNGSTATE(VI)ION | Authors: | Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L. | Deposit date: | 2005-03-07 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Purified Argonaute2 and an siRNA form recombinant human RISC. Nat.Struct.Mol.Biol., 12, 2005
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1Z25
| Structure of P.furiosus Argonaute with bound Mn2+ | Descriptor: | Argonaute, MANGANESE (II) ION | Authors: | Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L. | Deposit date: | 2005-03-07 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Purified Argonaute2 and an siRNA form recombinant human RISC. Nat.Struct.Mol.Biol., 12, 2005
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8DCE
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8E1Z
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7JGG
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8DFG
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8DFH
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8DFI
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7JGF
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7JGE
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8EZL
| Pfs25 in complex with transmission-reducing antibody AS01-50 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ... | Authors: | Shukla, N, Tang, W.K, Tolia, N.H. | Deposit date: | 2022-11-01 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A human antibody epitope map of the malaria vaccine antigen Pfs25. Npj Vaccines, 8, 2023
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8EZM
| Pfs25 in complex with transmission-reducing antibody AS01-63 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, SULFATE ION, ... | Authors: | Shukla, N, Tang, W.K, Tolia, N.H. | Deposit date: | 2022-11-01 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A human antibody epitope map of the malaria vaccine antigen Pfs25. Npj Vaccines, 8, 2023
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8EZK
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8ER1
| X-ray crystal structure of Tet(X6) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase | Authors: | Kumar, H, Tolia, N.H. | Deposit date: | 2022-10-11 | Release date: | 2023-04-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases. Commun Biol, 6, 2023
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8ER0
| X-ray crystal structure of Tet(X6) bound to anhydrotetracycline | Descriptor: | 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase | Authors: | Kumar, H, Tolia, N.H. | Deposit date: | 2022-10-11 | Release date: | 2023-04-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases. Commun Biol, 6, 2023
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7JGH
| Cryo-EM structure of P. falciparum VAR2CSA NF54 core in complex with CSA at 3.36 A | Descriptor: | 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, Erythrocyte membrane protein 1, beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid | Authors: | Ma, R, Tolia, N.H. | Deposit date: | 2020-07-19 | Release date: | 2021-01-13 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA. Nat Microbiol, 6, 2021
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7JGD
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5TUM
| Crystal structure of tetracycline destructase Tet(56) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, tetracycline destructase Tet(56) | Authors: | Park, J, Tolia, N.H. | Deposit date: | 2016-11-06 | Release date: | 2017-05-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.299 Å) | Cite: | Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes. Nat. Chem. Biol., 13, 2017
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5TUF
| Crystal structure of tetracycline destructase Tet(50) in complex with anhydrotetracycline | Descriptor: | 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | Authors: | Park, J, Tolia, N.H. | Deposit date: | 2016-11-06 | Release date: | 2017-05-10 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes. Nat. Chem. Biol., 13, 2017
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5TUL
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