3K3H
| Crystal structure of the PDE9A catalytic domain in complex with (S)-BAY73-6691 | Descriptor: | 1-(2-chlorophenyl)-6-[(2S)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | Authors: | Wang, H, Luo, X, Ye, M, Hou, J, Robinson, H, Ke, H. | Deposit date: | 2009-10-02 | Release date: | 2010-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insight into Binding of Phosphodiesterase-9A Selective Inhibitors by Crystal Structures and Mutagenesis J.Med.Chem., 53, 2010
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7MPS
| Brucella melitensis NrnC with engaged loop | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NanoRNase C, SULFATE ION | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2021-05-04 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MQB
| Bartonella henselae NrnC bound to pGG. D4 Symmetry | Descriptor: | NanoRNase C, RNA (5'-R(P*GP*G)-3') | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | Deposit date: | 2021-05-05 | Release date: | 2021-09-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MQD
| Bartonella henselae NrnC complexed with pAGG. D4 symmetry. | Descriptor: | NanoRNase C, RNA (5'-R(P*AP*GP*G)-3') | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | Deposit date: | 2021-05-05 | Release date: | 2021-09-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MPL
| Bartonella henselae NrnC bound to pGG | Descriptor: | 5'-phosphorylated GG, NanoRNase C | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2021-05-04 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MPP
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7MQG
| Bartonella henselae NrnC complexed with pAAAGG. C1 reconstruction. | Descriptor: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | Deposit date: | 2021-05-05 | Release date: | 2021-09-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MPR
| Brucella melitensis NrnC | Descriptor: | NanoRNase C, SULFATE ION | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2021-05-04 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MPM
| Bartonella henselae NrnC bound to pAA | Descriptor: | 5'-phosphorylated AA, NanoRNase C | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2021-05-04 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MQC
| Bartonella henselae NrnC bound to pGG. C1 reconstruction. | Descriptor: | NanoRNase C, RNA (5'-R(P*GP*G)-3') | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | Deposit date: | 2021-05-05 | Release date: | 2021-09-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MPO
| Bartonella henselae NrnC bound to pAp | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, NanoRNase C | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2021-05-04 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MPN
| Bartonella henselae NrnC bound to pGC | Descriptor: | 5'-phosphorylated GC, NanoRNase C | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2021-05-04 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MQI
| Bartonella henselae NrnC complexed with pAAAGG in the presence of Ca2+. C1 reconstruction. | Descriptor: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | Deposit date: | 2021-05-05 | Release date: | 2021-09-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MPQ
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7MQH
| Bartonella henselae NrnC complexed with pAAAGG in the presence of Ca2+. D4 Symmetry. | Descriptor: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | Deposit date: | 2021-05-05 | Release date: | 2021-09-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MPT
| Brucella melitensis NrnC with bound Mg2+ | Descriptor: | MAGNESIUM ION, NanoRNase C, PHOSPHATE ION | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2021-05-04 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MQF
| Bartonella henselae NrnC complexed with pAAAGG. D4 symmetry. | Descriptor: | NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3') | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | Deposit date: | 2021-05-05 | Release date: | 2021-09-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MPU
| Brucella melitensis NrnC bound to pGG | Descriptor: | 5'-phosphorylated GG, NanoRNase C, SULFATE ION | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2021-05-04 | Release date: | 2021-09-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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7MQE
| Bartonella henselae NrnC complexed with pAGG. C1 reconstruction. | Descriptor: | NanoRNase C, RNA (5'-R(P*AP*GP*G)-3') | Authors: | Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H. | Deposit date: | 2021-05-05 | Release date: | 2021-09-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Structural characterization of NrnC identifies unifying features of dinucleotidases. Elife, 10, 2021
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3K3E
| Crystal structure of the PDE9A catalytic domain in complex with (R)-BAY73-6691 | Descriptor: | 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... | Authors: | Wang, H, Luo, X, Ye, M, Hou, J, Robinson, H, Ke, H. | Deposit date: | 2009-10-02 | Release date: | 2010-02-16 | Last modified: | 2013-11-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Insight into Binding of Phosphodiesterase-9A Selective Inhibitors by Crystal Structures and Mutagenesis J.Med.Chem., 53, 2010
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3OGG
| Crystal structure of the receptor binding domain of botulinum neurotoxin D | Descriptor: | Botulinum neurotoxin type D | Authors: | Zhang, Y, Gao, X, Qin, L, Buchko, G.W, Robinson, H, Varnum, S.M. | Deposit date: | 2010-08-16 | Release date: | 2010-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.651 Å) | Cite: | Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D. Biochem.Biophys.Res.Commun., 401, 2010
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3BRE
| Crystal Structure of P.aeruginosa PA3702 | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Probable two-component response regulator | Authors: | De, N, Pirruccello, M, Krasteva, P.V, Bae, N, Raghavan, R.V, Sondermann, H. | Deposit date: | 2007-12-21 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Phosphorylation-independent regulation of the diguanylate cyclase WspR. Plos Biol., 6, 2008
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3F99
| W354F Yersinia enterocolitica PTPase apo form | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase yopH | Authors: | Brandao, T.A.S, Robinson, H, Johnson, S.J, Hengge, A.C. | Deposit date: | 2008-11-13 | Release date: | 2009-01-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures. J.Am.Chem.Soc., 131, 2009
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2ZJG
| Crystal structural of mouse kynurenine aminotransferase III | Descriptor: | GLYCEROL, Kynurenine-oxoglutarate transaminase 3 | Authors: | Han, Q, Cai, T, Tagle, D.A, Robinson, H, Li, J. | Deposit date: | 2008-03-07 | Release date: | 2009-01-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and functional characterization of mouse kynurenine aminotransferase III To be Published
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3D0S
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