1U5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1u5i by Molmil](/molmil-images/mine/1u5i) | Crystal Structure analysis of rat m-calpain mutant Lys10 Thr | Descriptor: | Calpain 2, large [catalytic] subunit precursor, Calpain small subunit 1 | Authors: | Hosfield, C.M, Pal, G.P, Elce, J.S, Jia, Z. | Deposit date: | 2004-07-27 | Release date: | 2005-01-18 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Activation of calpain by Ca2+: roles of the large subunit N-terminal and domain III-IV linker peptides J.Mol.Biol., 343, 2004
|
|
1DF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1df0 by Molmil](/molmil-images/mine/1df0) | Crystal structure of M-Calpain | Descriptor: | CALPAIN, M-CALPAIN | Authors: | Hosfield, C.M, Elce, J.S, Davies, P.L, Jia, Z. | Deposit date: | 1999-11-16 | Release date: | 2000-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation. EMBO J., 18, 1999
|
|
1KXR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kxr by Molmil](/molmil-images/mine/1kxr) | Crystal Structure of Calcium-Bound Protease Core of Calpain I | Descriptor: | CALCIUM ION, thiol protease DOMAINS I AND II | Authors: | Moldoveanu, T, Hosfield, C.M, Lim, D, Elce, J.S, Jia, Z, Davies, P.L. | Deposit date: | 2002-02-01 | Release date: | 2002-03-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | A Ca(2+) switch aligns the active site of calpain. Cell(Cambridge,Mass.), 108, 2002
|
|
1MDW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mdw by Molmil](/molmil-images/mine/1mdw) | Crystal Structure of Calcium-Bound Protease Core of Calpain II Reveals the Basis for Intrinsic Inactivation | Descriptor: | CALCIUM ION, Calpain II, catalytic subunit | Authors: | Moldoveanu, T, Hosfield, C.M, Lim, D, Jia, Z, Davies, P.L. | Deposit date: | 2002-08-07 | Release date: | 2003-04-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Calpain silencing by a reversible intrinsic mechanism. Nat.Struct.Biol., 10, 2003
|
|
3DF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3df0 by Molmil](/molmil-images/mine/3df0) | Calcium-dependent complex between m-calpain and calpastatin | Descriptor: | CALCIUM ION, Calpain small subunit 1, Calpain-2 catalytic subunit, ... | Authors: | Moldoveanu, T, Gehring, K, Green, D.R. | Deposit date: | 2008-06-11 | Release date: | 2008-11-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains. Nature, 456, 2008
|
|
1TL9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tl9 by Molmil](/molmil-images/mine/1tl9) | High resolution crystal structure of calpain I protease core in complex with leupeptin | Descriptor: | CALCIUM ION, Calpain 1, large [catalytic] subunit, ... | Authors: | Moldoveanu, T, Campbell, R.L, Cuerrier, D, Davies, P.L. | Deposit date: | 2004-06-09 | Release date: | 2004-11-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site J.Mol.Biol., 343, 2004
|
|
1TLO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tlo by Molmil](/molmil-images/mine/1tlo) | High resolution crystal structure of calpain I protease core in complex with E64 | Descriptor: | CALCIUM ION, Calpain 1, large [catalytic] subunit, ... | Authors: | Moldoveanu, T, Campbell, R.L, Cuerrier, D, Davies, P.L. | Deposit date: | 2004-06-09 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site J.Mol.Biol., 343, 2004
|
|