5A5Z
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![BU of 5a5z by Molmil](/molmil-images/mine/5a5z) | Approved Drugs Containing Thiols as Inhibitors of Metallo-beta- lactamases: Strategy To Combat Multidrug-Resistant Bacteria | Descriptor: | BETA-LACTAMASE NDM-1, TIOPRONIN, ZINC ION | Authors: | Klingler, F.M, Wichelhaus, T.A, Frank, D, Cuesta-Bernal, J, El-Delik, J, Mueller, H.F, Sjuts, H, Goettig, S, Koenigs, A, Pogoryelov, D, Proschak, E. | Deposit date: | 2015-06-23 | Release date: | 2015-07-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Approved Drugs Containing Thiols as Inhibitors of Metallo-beta-lactamases: Strategy To Combat Multidrug-Resistant Bacteria. J. Med. Chem., 58, 2015
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5NIW
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![BU of 5niw by Molmil](/molmil-images/mine/5niw) | Glucose oxydase mutant A2 | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | Authors: | Hoffmann, K, Frank, D. | Deposit date: | 2017-03-27 | Release date: | 2017-11-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Shuffling Active Site Substate Populations Affects Catalytic Activity: The Case of Glucose Oxidase. ACS Catal, 7, 2017
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2J9N
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![BU of 2j9n by Molmil](/molmil-images/mine/2j9n) | Robotically harvested Trypsin complexed with Benzamidine containing polypeptide mediated crystal contacts | Descriptor: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | Authors: | Viola, R, Carman, P, Walsh, J, Miller, E, Benning, M, Frankel, D, McPherson, A, Cudney, R, Rupp, B. | Deposit date: | 2006-11-14 | Release date: | 2007-04-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Operator Assisted Harvesting of Protein Crystals Using a Universal Micromanipulation Robot. J.Appl.Crystallogr., 40, 2007
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5O7N
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![BU of 5o7n by Molmil](/molmil-images/mine/5o7n) | Beta-lactamase VIM-2 in complex with (2R)-1-(2-Benzyl-3-mercaptopropanoyl)piperidine-2-carboxylic acid | Descriptor: | (2~{R})-1-[(2~{S})-2-(phenylmethyl)-3-sulfanyl-propanoyl]piperidine-2-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase VIM-2, ... | Authors: | Buettner, D, Kramer, J.S, Pogoryelov, D, Proschak, E. | Deposit date: | 2017-06-09 | Release date: | 2018-06-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-beta-Lactamases. Acs Infect Dis., 4, 2018
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5NIT
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![BU of 5nit by Molmil](/molmil-images/mine/5nit) | Glucose oxidase mutant A2 | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Hoffmann, K. | Deposit date: | 2017-03-27 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Shuffling Active Site Substate Populations Affects Catalytic Activity: The Case of Glucose Oxidase. ACS Catal, 7, 2017
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8LPR
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![BU of 8lpr by Molmil](/molmil-images/mine/8lpr) | |
9LPR
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![BU of 9lpr by Molmil](/molmil-images/mine/9lpr) | |
6LPR
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![BU of 6lpr by Molmil](/molmil-images/mine/6lpr) | |
1P03
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![BU of 1p03 by Molmil](/molmil-images/mine/1p03) | |
5LPR
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![BU of 5lpr by Molmil](/molmil-images/mine/5lpr) | |
3LPR
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![BU of 3lpr by Molmil](/molmil-images/mine/3lpr) | |
5NBK
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![BU of 5nbk by Molmil](/molmil-images/mine/5nbk) | NDM-1 metallo-beta-lactamase: a parsimonious interpretation of the diffraction data | Descriptor: | CHLORIDE ION, HEXAETHYLENE GLYCOL, Metallo-beta-lactamase type 2, ... | Authors: | Raczynska, J.E, Shabalin, I.G, Jaskolski, M, Minor, W, Wlodawer, A. | Deposit date: | 2017-03-02 | Release date: | 2018-10-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A close look onto structural models and primary ligands of metallo-beta-lactamases. Drug Resist. Updat., 40, 2018
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2ULL
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![BU of 2ull by Molmil](/molmil-images/mine/2ull) | |
7LPR
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![BU of 7lpr by Molmil](/molmil-images/mine/7lpr) | |
1BOQ
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![BU of 1boq by Molmil](/molmil-images/mine/1boq) | PRO REGION C-TERMINUS: PROTEASE ACTIVE SITE INTERACTIONS ARE CRITICAL IN CATALYZING THE FOLDING OF ALPHA-LYTIC PROTEASE | Descriptor: | PROTEIN (ALPHA-LYTIC PROTEASE), SULFATE ION | Authors: | Peters, R.J, Shiau, A.K, Sohl, J.L, Anderson, D.E, Tang, G, Silen, J.L, Agard, D.A. | Deposit date: | 1998-08-05 | Release date: | 1998-08-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Pro region C-terminus:protease active site interactions are critical in catalyzing the folding of alpha-lytic protease. Biochemistry, 37, 1998
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1P04
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![BU of 1p04 by Molmil](/molmil-images/mine/1p04) | |
1P05
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![BU of 1p05 by Molmil](/molmil-images/mine/1p05) | |
1P02
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![BU of 1p02 by Molmil](/molmil-images/mine/1p02) | |
1P06
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![BU of 1p06 by Molmil](/molmil-images/mine/1p06) | |
2LPR
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![BU of 2lpr by Molmil](/molmil-images/mine/2lpr) | |
1GBK
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![BU of 1gbk by Molmil](/molmil-images/mine/1gbk) | |
1GBF
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![BU of 1gbf by Molmil](/molmil-images/mine/1gbf) | |
1GBD
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![BU of 1gbd by Molmil](/molmil-images/mine/1gbd) | |
1GBM
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![BU of 1gbm by Molmil](/molmil-images/mine/1gbm) | |
1GBA
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![BU of 1gba by Molmil](/molmil-images/mine/1gba) | |