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5SRV
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BU of 5srv by Molmil
PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5198562533 - (R,R) isomer
Descriptor: (3R,4R)-4-cyclopropyl-3-fluoro-1-(7-fluoro-9H-pyrimido[4,5-b]indol-4-yl)pyrrolidine-3-carboxylic acid, Non-structural protein 3
Authors:Correy, G.J, Fraser, J.S.
Deposit date:2022-06-09
Release date:2022-07-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
5SRU
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BU of 5sru by Molmil
PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5198562523 - (S) isomer
Descriptor: (8S)-6-(7-fluoro-9H-pyrimido[4,5-b]indol-4-yl)-6-azaspiro[3.4]octane-8-carboxylic acid, Non-structural protein 3
Authors:Correy, G.J, Fraser, J.S.
Deposit date:2022-06-09
Release date:2022-07-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
5SRT
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BU of 5srt by Molmil
PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5198562791 - (R) isomer
Descriptor: 7-fluoro-4-[(2R)-2-(1H-tetrazol-5-yl)morpholin-4-yl]-9H-pyrimido[4,5-b]indole, Non-structural protein 3
Authors:Correy, G.J, Fraser, J.S.
Deposit date:2022-06-09
Release date:2022-07-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
5SSA
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BU of 5ssa by Molmil
PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINClv000001jcNa - (r,r) isomer
Descriptor: Non-structural protein 3, [(1r,3r)-3-{[(thieno[2,3-c]pyridine-5-carbonyl)amino]methyl}cyclobutyl]acetic acid
Authors:Correy, G.J, Fraser, J.S.
Deposit date:2022-06-09
Release date:2022-07-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
5SSQ
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BU of 5ssq by Molmil
PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5459166291
Descriptor: 3-{[(1H-benzimidazole-5-carbonyl)amino]methyl}-1H-indole-2-carboxylic acid, Non-structural protein 3
Authors:Correy, G.J, Fraser, J.S.
Deposit date:2022-06-09
Release date:2022-07-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
4G7V
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BU of 4g7v by Molmil
Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.5 A)
Descriptor: CHLORIDE ION, LAURYL DIMETHYLAMINE-N-OXIDE, SUCCINIC ACID, ...
Authors:Li, Q.
Deposit date:2012-07-20
Release date:2014-02-05
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Nat. Struct. Mol. Biol., 21, 2014
4G7Y
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BU of 4g7y by Molmil
Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.8 A)
Descriptor: CHLORIDE ION, Fragment antibody heavy chain, Fragment antibody light chain, ...
Authors:Li, Q.
Deposit date:2012-07-20
Release date:2014-02-05
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Nat. Struct. Mol. Biol., 21, 2014
7BTI
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BU of 7bti by Molmil
Phalloidin bound F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kumari, A, Ragunath, V.K, Sirajuddin, M.
Deposit date:2020-04-01
Release date:2020-05-20
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into actin filament recognition by commonly used cellular actin markers.
Embo J., 39, 2020
5UE8
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BU of 5ue8 by Molmil
The crystal structure of Munc13-1 C1C2BMUN domain
Descriptor: CHLORIDE ION, Protein unc-13 homolog A, ZINC ION
Authors:Tomchick, D.R, Rizo, J, Xu, J.
Deposit date:2016-12-29
Release date:2017-02-15
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.
Elife, 6, 2017
7BTE
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BU of 7bte by Molmil
Lifeact-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kumari, A, Ragunath, V.K, Sirajuddin, M.
Deposit date:2020-04-01
Release date:2020-05-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural insights into actin filament recognition by commonly used cellular actin markers.
Embo J., 39, 2020
7BT7
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BU of 7bt7 by Molmil
F-actin-ADP complex structure
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kumari, A, Ragunath, V.K, Sirajuddin, M.
Deposit date:2020-03-31
Release date:2020-05-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into actin filament recognition by commonly used cellular actin markers.
Embo J., 39, 2020
7BJY
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BU of 7bjy by Molmil
Crystal structure of the first bromodomain (BD1) of human BRDT bound to Ro3280
Descriptor: 1,2-ETHANEDIOL, 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Isoform 2 of Bromodomain testis-specific protein
Authors:Chan, A, Karim, M.R, Schonbrunn, E.
Deposit date:2021-01-14
Release date:2021-08-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
J.Med.Chem., 64, 2021
1TFN
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BU of 1tfn by Molmil
STRUCTURE REFINEMENT FOR A 24-NUCLEOTIDE RNA HAIRPIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: RNA (5'-R(*GP*GP*GP*AP*CP*UP*GP*AP*CP*GP*AP*UP*CP*AP*CP*GP*CP*AP*GP*UP*CP*UP*AP*U)-3')
Authors:Kerwood, D.J, Borer, P.N.
Deposit date:1996-07-10
Release date:1997-02-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure Refinement for a 24-Nucleotide RNA Hairpin
MAGN.RESON.CHEM., 33, 1996
7W5Y
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BU of 7w5y by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with fpr promoter DNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y.
Deposit date:2021-11-30
Release date:2022-10-26
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7W5W
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BU of 7w5w by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with micF promoter DNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y.
Deposit date:2021-11-30
Release date:2022-10-26
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.55 Å)
Cite:Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7W5X
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BU of 7w5x by Molmil
Cryo-EM structure of SoxS-dependent transcription activation complex with zwf promoter DNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lin, W, Feng, Y, Shi, J.
Deposit date:2021-11-30
Release date:2022-10-26
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of three different transcription activation strategies adopted by a single regulator SoxS.
Nucleic Acids Res., 50, 2022
7WZ3
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BU of 7wz3 by Molmil
Cryo-EM structure of human TRiC-tubulin-S1 state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-02-16
Release date:2023-02-22
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X3U
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BU of 7x3u by Molmil
cryo-EM structure of human TRiC-ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-03-01
Release date:2023-06-07
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X3J
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BU of 7x3j by Molmil
Cryo-EM structure of human TRiC-tubulin-S2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-03-01
Release date:2023-06-07
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X6Q
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BU of 7x6q by Molmil
cryo-EM structure of human TRiC-ATP-closed state
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-03-08
Release date:2023-06-07
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X7Y
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BU of 7x7y by Molmil
Cryo-EM structure of Human TRiC-ATP-open state
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-03-10
Release date:2023-06-07
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X0V
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BU of 7x0v by Molmil
cryo-EM structure of human TRiC-ADP-AlFx
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-02-22
Release date:2023-04-12
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X0S
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BU of 7x0s by Molmil
Human TRiC-tubulin-S3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-02-22
Release date:2023-04-12
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X0A
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BU of 7x0a by Molmil
Cryo-EM structure of human TRiC-NPP state
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-02-21
Release date:2023-04-12
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
6M5G
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BU of 6m5g by Molmil
F-actin-Utrophin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kumari, A, Ragunath, V.K, Sirajuddin, M.
Deposit date:2020-03-10
Release date:2020-05-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into actin filament recognition by commonly used cellular actin markers.
Embo J., 39, 2020

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数据于2024-09-25公开中

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