8IY9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8iy9 by Molmil](/molmil-images/mine/8iy9) | Structure of Niacin-GPR109A-G protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | Authors: | Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-04-04 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. Nat Commun, 15, 2024
|
|
8JER
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jer by Molmil](/molmil-images/mine/8jer) | Structure of Acipimox-GPR109A-G protein complex | Descriptor: | 5-methyl-4-oxidanyl-pyrazin-4-ium-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yadav, M.K, Sarma, P, Chami, M, Banerjee, R, Shukla, A.K. | Deposit date: | 2023-05-16 | Release date: | 2024-03-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structure-guided engineering of biased-agonism in the human niacin receptor via single amino acid substitution. Nat Commun, 15, 2024
|
|
8JZZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jzz by Molmil](/molmil-images/mine/8jzz) | Structure of human C5a-desArg bound human C5aR1 in complex with Go | Descriptor: | Antibody fragment ScFv16, C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-07-06 | Release date: | 2023-10-18 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
|
|
3B7M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b7m by Molmil](/molmil-images/mine/3b7m) | |
8AS2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8as2 by Molmil](/molmil-images/mine/8as2) | Structure of arrestin2 in complex with 4P CCR5 phosphopeptide and Fab30 | Descriptor: | Beta-arrestin-1, C-C chemokine receptor type 5, Fab30 heavy chain, ... | Authors: | Isaikina, P, Jakob, R.P, Maier, T, Grzesiek, S. | Deposit date: | 2022-08-18 | Release date: | 2023-06-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes. Mol.Cell, 83, 2023
|
|
8AS3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8as3 by Molmil](/molmil-images/mine/8as3) | Structure of arrestin2 in complex with 6P CCR5 phosphopeptide and Fab30 | Descriptor: | Beta-arrestin-1, C-C chemokine receptor type 5, Fab30 heavy chain, ... | Authors: | Isaikina, P, Jakob, R.P, Maier, T, Grzesiek, S. | Deposit date: | 2022-08-18 | Release date: | 2023-06-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes. Mol.Cell, 83, 2023
|
|
8AS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8as4 by Molmil](/molmil-images/mine/8as4) | |
8IA2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ia2 by Molmil](/molmil-images/mine/8ia2) | Structure of C5a bound human C5aR1 in complex with Go (Composite map) | Descriptor: | Antibody fragment - ScFv16, C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-02-07 | Release date: | 2023-10-18 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
|
|
8J97
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j97 by Molmil](/molmil-images/mine/8j97) | Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local refine, cross-linked) | Descriptor: | Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K. | Deposit date: | 2023-05-02 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
|
|
8JAF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jaf by Molmil](/molmil-images/mine/8jaf) | Structure of Muscarinic receptor (M2R) in complex with beta-arrestin1 (Local Refine, non-cross linked) | Descriptor: | Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ... | Authors: | Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K. | Deposit date: | 2023-05-05 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
|
|
8J8R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8j8r by Molmil](/molmil-images/mine/8j8r) | Structure of beta-arrestin2 in complex with M2Rpp | Descriptor: | Beta-arrestin-2, Fab30 Heavy Chain, Fab30 Light Chain, ... | Authors: | Maharana, J, Sano, F.K, Shihoya, W, Banerjee, R, Nureki, O, Shukla, A.K. | Deposit date: | 2023-05-02 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
|
|
7O9F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o9f by Molmil](/molmil-images/mine/7o9f) | Bacillus subtilis Ffh in complex with ppGpp | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, Signal recognition particle protein | Authors: | Czech, L, Mais, C.-N, Bange, G. | Deposit date: | 2021-04-16 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp. Nat Commun, 13, 2022
|
|
7O9I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o9i by Molmil](/molmil-images/mine/7o9i) | Escherichia coli Ffh in complex with pppGpp | Descriptor: | Signal recognition particle protein, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate) | Authors: | Czech, L, Mais, C.-N, Bange, G. | Deposit date: | 2021-04-16 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp. Nat Commun, 13, 2022
|
|
7O9G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o9g by Molmil](/molmil-images/mine/7o9g) | Escherichia coli Ffh in complex with ppGpp | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, Signal recognition particle protein | Authors: | Czech, L, Mais, C.-N, Bange, G. | Deposit date: | 2021-04-16 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp. Nat Commun, 13, 2022
|
|
7O9H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o9h by Molmil](/molmil-images/mine/7o9h) | Escherichia coli FtsY in complex with pppGpp | Descriptor: | Signal recognition particle receptor FtsY, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate) | Authors: | Czech, L, Mais, C.-N, Bange, G. | Deposit date: | 2021-04-16 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp. Nat Commun, 13, 2022
|
|
7O5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7o5b by Molmil](/molmil-images/mine/7o5b) | Cryo-EM structure of a Bacillus subtilis MifM-stalled ribosome-nascent chain complex with (p)ppGpp-SRP bound | Descriptor: | 16S rRNA (1533-MER), 23S rRNA (2887-MER), 30S ribosomal protein S10, ... | Authors: | Kratzat, H, Czech, L, Berninghausen, O, Bange, G, Beckmann, R. | Deposit date: | 2021-04-08 | Release date: | 2022-02-02 | Last modified: | 2022-03-09 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp. Nat Commun, 13, 2022
|
|