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5V4M
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BU of 5v4m by Molmil
Structure of HLA-DR15 with bound alpha3(135-145) peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, ...
Authors:Petersen, J, Rossjohn, J.
Deposit date:2017-03-10
Release date:2017-05-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017
4LCW
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BU of 4lcw by Molmil
The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH
Descriptor: 1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
Authors:Patel, O, Rossjohn, J.
Deposit date:2013-06-24
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells.
J.Exp.Med., 210, 2013
6ATF
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BU of 6atf by Molmil
HLA-DRB1*1402 in complex with Vimentin59-71
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Scally, S.W, Ting, Y.T, Rossjohn, J.
Deposit date:2017-08-29
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
Ann. Rheum. Dis., 76, 2017
3SDC
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BU of 3sdc by Molmil
Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-globotrihexosylceramide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Clarke, A.J, Rossjohn, J.
Deposit date:2011-06-09
Release date:2011-10-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors
Nat.Immunol., 12, 2011
3SDA
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BU of 3sda by Molmil
Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-beta-galactosylceramide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Clarke, A.J, Rossjohn, J.
Deposit date:2011-06-08
Release date:2011-10-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors
Nat.Immunol., 12, 2011
5V4N
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BU of 5v4n by Molmil
Structure of HLA-DR1 with bound alpha3(135-145) peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, alpha3(135-145)-HLA-DRB1*01:01
Authors:Petersen, J, Rossjohn, J.
Deposit date:2017-03-10
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.405 Å)
Cite:Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017
4L6T
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BU of 4l6t by Molmil
GM1 bound form of the ECX AB5 holotoxin
Descriptor: ECXA, ECXB, ZINC ION, ...
Authors:Littler, D.R, Ng, N.M, Rossjohn, J, Beddoe, T.
Deposit date:2013-06-12
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.859 Å)
Cite:EcxAB Is a Founding Member of a New Family of Metalloprotease AB5 Toxins with a Hybrid Cholera-like B Subunit.
Structure, 21, 2013
3SDD
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BU of 3sdd by Molmil
Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-beta-lactosylceramide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Clarke, A.J, Rossjohn, J.
Deposit date:2011-06-09
Release date:2011-10-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors
Nat.Immunol., 12, 2011
4JQX
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BU of 4jqx by Molmil
HLA-B*44:03 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 169-180)
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
Authors:Theodossis, A, Welland, A, Gras, S, Rossjohn, J.
Deposit date:2013-03-20
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:HLA Peptide Length Preferences Control CD8+ T Cell Responses.
J.Immunol., 191, 2013
3SCM
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BU of 3scm by Molmil
Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-isoglobotrihexosylceramide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Clarke, A.J, Rossjohn, J.
Deposit date:2011-06-08
Release date:2011-10-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors
Nat.Immunol., 12, 2011
3TO4
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BU of 3to4 by Molmil
Structure of mouse Valpha14Vbeta2-mouseCD1d-alpha-Galactosylceramide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Patel, O, Rossjohn, J.
Deposit date:2011-09-04
Release date:2011-12-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Vbeta2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen.
Proc.Natl.Acad.Sci.USA, 108, 2011
3DX6
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BU of 3dx6 by Molmil
Crystal Structure of B*4402 presenting a 10mer EBV epitope
Descriptor: ACETATE ION, Beta-2-microglobulin, EBV decapeptide epitope, ...
Authors:Archbold, J.K, Ely, L.K, Rossjohn, J.
Deposit date:2008-07-23
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
J.Exp.Med., 206, 2009
6ATZ
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BU of 6atz by Molmil
HLA-DRB1*1402 in complex with citrullinated fibrinogen peptide
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta chain, ...
Authors:Ting, Y.T, Scally, S.W, Rossjohn, J.
Deposit date:2017-08-29
Release date:2017-09-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
Ann. Rheum. Dis., 76, 2017
6ATI
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BU of 6ati by Molmil
HLA-DRB1*1402 in complex with Vimentin-64Cit59-71
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ...
Authors:Scally, S.W, Ting, Y.T, Rossjohn, J.
Deposit date:2017-08-29
Release date:2017-09-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
Ann. Rheum. Dis., 76, 2017
4L63
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BU of 4l63 by Molmil
Apo form of AB5 holotoxin
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ECXA, ECXB, ...
Authors:Littler, D.R, Ng, N.M, Rossjohn, J, Beddoe, T.
Deposit date:2013-06-11
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:EcxAB Is a Founding Member of a New Family of Metalloprotease AB5 Toxins with a Hybrid Cholera-like B Subunit.
Structure, 21, 2013
6D2B
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BU of 6d2b by Molmil
HLA-B*57:01 presenting LSDSTARDVTW
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
Authors:Vivian, J.P, Rossjohn, J.
Deposit date:2018-04-13
Release date:2018-10-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands.
Sci Immunol, 3, 2018
4JQV
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BU of 4jqv by Molmil
HLA-B*18:01 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 173-180)
Descriptor: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Theodossis, A, Welland, A, Gras, S, Rossjohn, J.
Deposit date:2013-03-20
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:HLA Peptide Length Preferences Control CD8+ T Cell Responses.
J.Immunol., 191, 2013
3HE6
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BU of 3he6 by Molmil
Crystal structure of mouse CD1d-alpha-galactosylceramide with mouse Valpha14-Vbeta8.2 NKT TCR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Patel, O, Rossjohn, J.
Deposit date:2009-05-07
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors
Immunity, 31, 2009
3HE7
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BU of 3he7 by Molmil
Crystal structure of mouse CD1d-alpha-galactosylceramide with mouse Valpha14-Vbeta7 NKT TCR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
Authors:Patel, O, Rossjohn, J.
Deposit date:2009-05-08
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Differential recognition of CD1d-alpha-galactosyl ceramide by the V beta 8.2 and V beta 7 semi-invariant NKT T cell receptors
Immunity, 31, 2009
4X6D
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BU of 4x6d by Molmil
CD1a ternary complex with endogenous lipids and BK6 TCR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, OLEIC ACID, ...
Authors:Birkinshaw, R.W, Rossjohn, J.
Deposit date:2014-12-08
Release date:2015-01-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:alpha beta T cell antigen receptor recognition of CD1a presenting self lipid ligands.
Nat.Immunol., 16, 2015
3VK1
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BU of 3vk1 by Molmil
Green-fluorescent variant of the non-fluorescent chromoprotein Rtms5
Descriptor: CHLORIDE ION, GFP-like non-fluorescent chromoprotein, IODIDE ION
Authors:Battad, J.M, Traore, D.A.K, Wilce, M, Byres, M, Rossjohn, J, Devenish, R.J, Prescott, M.
Deposit date:2011-11-07
Release date:2012-06-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Green Fluorescent Protein Containing a QFG Tri-Peptide Chromophore: Optical Properties and X-Ray Crystal Structure.
Plos One, 7, 2012
4GSS
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BU of 4gss by Molmil
HUMAN GLUTATHIONE S-TRANSFERASE P1-1 Y108F MUTANT
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE, S-HEXYLGLUTATHIONE
Authors:Oakley, A, Rossjohn, J, Parker, M.
Deposit date:1997-01-20
Release date:1998-01-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme.
Biochemistry, 36, 1997
8T4Z
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BU of 8t4z by Molmil
T-cell receptor and lipid complex structure
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, ...
Authors:Praveena, T, Rossjohn, J.
Deposit date:2023-06-12
Release date:2024-08-07
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (2.691 Å)
Cite:Lipidomic scanning of self-lipids identifies headless antigens for natural killer T cells.
Proc.Natl.Acad.Sci.USA, 121, 2024
5U17
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BU of 5u17 by Molmil
Structure of human MR1-DA-6-FP in complex with human MAIT A-F7 TCR
Descriptor: 2,4-diaminopteridine-6-carbaldehyde, ACETATE ION, Beta-2-microglobulin, ...
Authors:Keller, A.N, Rossjohn, J.
Deposit date:2016-11-28
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Nat. Immunol., 18, 2017
5U2V
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BU of 5u2v by Molmil
Structure of human MR1-HMB in complex with human MAIT A-F7 TCR
Descriptor: 2-hydroxy-5-methoxybenzaldehyde, Beta-2-microglobulin, GLYCEROL, ...
Authors:Keller, A.N, Rossjohn, J.
Deposit date:2016-12-01
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Nat. Immunol., 18, 2017

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数据于2024-09-25公开中

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