6T9D
| Crystal structure of a bispecific DutaFab in complex with human VEGF121 | Descriptor: | VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | Deposit date: | 2019-10-28 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.905 Å) | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
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6T9E
| Crystal structure of a bispecific DutaFab in complex with human PDGF | Descriptor: | DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B | Authors: | Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. | Deposit date: | 2019-10-28 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.989 Å) | Cite: | DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
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3TOI
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7TFB
| P. polymyxa GS(14)-Q-GlnR peptide | Descriptor: | GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ... | Authors: | Travis, B.A, Peck, J, Schumacher, M.A. | Deposit date: | 2022-01-06 | Release date: | 2022-06-29 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.28 Å) | Cite: | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TF7
| S. aureus GS(12) - apo | Descriptor: | Glutamine synthetase | Authors: | Travis, B.A, Peck, J, Schumacher, M.A. | Deposit date: | 2022-01-06 | Release date: | 2022-06-29 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.13 Å) | Cite: | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TF9
| L. monocytogenes GS(14)-Q-GlnR peptide | Descriptor: | C-tail peptide of Glutamine synthetase repressor, GLUTAMINE, Glutamine synthetase, ... | Authors: | Travis, B.A, Peck, J, Schumacher, M.A. | Deposit date: | 2022-01-06 | Release date: | 2022-06-29 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TFA
| P. polymyxa GS(12)-Q-GlnR peptide | Descriptor: | GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ... | Authors: | Travis, B.A, Peck, J, Schumacher, M.A. | Deposit date: | 2022-01-06 | Release date: | 2022-06-29 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.07 Å) | Cite: | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TF6
| S. aureus GS(12)-Q-GlnR peptide | Descriptor: | GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... | Authors: | Travis, B.A, Peck, J, Schumacher, M.A. | Deposit date: | 2022-01-06 | Release date: | 2022-06-29 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.15 Å) | Cite: | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TFE
| L. monocytogenes GS(12) - apo | Descriptor: | Glutamine synthetase, MAGNESIUM ION | Authors: | Travis, B.A, Peck, J, Schumacher, M.A. | Deposit date: | 2022-01-06 | Release date: | 2022-06-29 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TFC
| B. subtilis GS(14)-Q-GlnR peptide | Descriptor: | GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ... | Authors: | Travis, B.A, Peck, J, Schumacher, M.A. | Deposit date: | 2022-01-06 | Release date: | 2022-06-29 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (1.96 Å) | Cite: | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TFD
| P. polymyxa GS(12) - apo | Descriptor: | Glutamine synthetase, MAGNESIUM ION | Authors: | Travis, B.A, Peck, J, Schumacher, M.A. | Deposit date: | 2022-01-06 | Release date: | 2022-06-29 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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5O46
| Crystal structure of Iristatin, a secreted salivary cystatin from the hard tick Ixodes ricinus | Descriptor: | GLYCEROL, Iristatin | Authors: | Busa, M, Rezacova, P, Kotal, J, Kotsyfakis, M, Mares, M. | Deposit date: | 2017-05-26 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin. Cell.Mol.Life Sci., 76, 2019
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3L0R
| Crystal Structure of Salivary Cystatin from the Soft Tick Ornithodoros moubata | Descriptor: | CHLORIDE ION, Cystatin-2, GLYCEROL | Authors: | Rezacova, P, Brynda, J, Andersen, J.F, Salat, J, Kovarova, Z, Mares, M. | Deposit date: | 2009-12-10 | Release date: | 2010-06-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata Biochem.J., 429, 2010
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3NDA
| Crystal structure of serpin from tick Ixodes ricinus | Descriptor: | PENTAETHYLENE GLYCOL, Serpin-2 | Authors: | Rezacova, P, Kovarova, Z, Chmelar, J, Mares, M. | Deposit date: | 2010-06-07 | Release date: | 2010-10-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation. Blood, 117, 2011
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4C7N
| Crystal Structure of the synthetic peptide iM10 in complex with the coiled-coil region of MITF | Descriptor: | MERCURY (II) ION, MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR, SYNTHETIC ALPHA-HELIX, ... | Authors: | Wohlwend, D, Gerhardt, S, Kuekenshoener, T, Einsle, O. | Deposit date: | 2013-09-23 | Release date: | 2014-04-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Improving Coiled Coil Stability While Maintaining Specificity by a Bacterial Hitchhiker Selection System. J.Struct.Biol., 186, 2014
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