6CW3
 
 | | Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 2 | | Descriptor: | Histone acetyltransferase GCN5, Transcriptional adapter 2, ZINC ION, ... | | Authors: | Sun, J, Paduch, M, Kim, S.A, Kramer, R.M, Barrios, A.F, Lu, V, Luke, J, Usatyuk, S, Kossiakoff, A.A, Tan, S. | | Deposit date: | 2018-03-29 | | Release date: | 2018-09-19 | | Last modified: | 2020-03-04 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5HQ2
 | | Structural model of Set8 histone H4 Lys20 methyltransferase bound to nucleosome core particle | | Descriptor: | DNA (149-MER), Guanine nucleotide exchange factor SRM1, Histone H2A, ... | | Authors: | Tavarekere, G, McGinty, R.K, Tan, S. | | Deposit date: | 2016-01-21 | | Release date: | 2016-03-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate.
J.Mol.Biol., 428, 2016
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5IJA
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2ROZ
 | | Structure of the C-terminal PID Domain of Fe65L1 Complexed with the Cytoplasmic Tail of APP Reveals a Novel Peptide Binding Mode | | Descriptor: | Amyloid beta A4 precursor protein-binding family B member 2, peptide from Amyloid beta A4 protein | | Authors: | Li, H, Koshiba, S, Tochio, N, Watanabe, S, Harada, T, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2008-04-25 | | Release date: | 2008-07-22 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode
J.Biol.Chem., 283, 2008
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8Y4B
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8Y46
 | | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to L-KDF or L-2,4-DKDF | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, L-2,4-diketo-3-deoxyfuconate, ... | | Authors: | Akagashi, M, Watanabe, S. | | Deposit date: | 2024-01-30 | | Release date: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase reveals a unique binding mode as a alpha-furanosyl hemiketal of substrates.
Sci Rep, 14, 2024
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8Y11
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8XWK
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8Y4J
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2RRF
 | | The solution structure of the C-terminal region of Zinc finger FYVE domain-containing protein 21 | | Descriptor: | Zinc finger FYVE domain-containing protein 21 | | Authors: | Koshiba, S, Tomizawa, T, Hayashi, F, Tochio, N, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S. | | Deposit date: | 2010-08-03 | | Release date: | 2011-08-03 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | ZF21 protein, a regulator of the disassembly of focal adhesions and cancer metastasis, contains a novel noncanonical pleckstrin homology domain
J.Biol.Chem., 286, 2011
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2RNL
 | | Solution structure of the EGF-like domain from human Amphiregulin | | Descriptor: | Amphiregulin | | Authors: | Qin, X, Hayashi, F, Terada, T, Shirouzu, M, Watanabe, S, Kigawa, T, Yabuta, N, Nojima, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2008-01-11 | | Release date: | 2009-01-20 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the EGF-like domain from human Amphiregulin
To be Published
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6ISC
 | | complex structure of mCD226-ecto and hCD155-D1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD226 antigen, Poliovirus receptor | | Authors: | Wang, H, Qi, J, Zhang, S, Li, Y, Tan, S, Gao, G.F. | | Deposit date: | 2018-11-16 | | Release date: | 2018-12-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Binding mode of the side-by-side two-IgV molecule CD226/DNAM-1 to its ligand CD155/Necl-5.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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8YIB
 | | Staphylococcus aureus lipase -PSA complex - covalent bonding state | | Descriptor: | ACETIC ACID, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Kitadokoro, J, Kamitani, S, Kitadokoro, K. | | Deposit date: | 2024-02-29 | | Release date: | 2024-06-05 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Crystal structure of Staphylococcus aureus lipase complex with unsaturated petroselinic acid.
Febs Open Bio, 14, 2024
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5XJ3
 | | Complex structure of ipilimumab-scFv and CTLA-4 | | Descriptor: | Cytotoxic T-lymphocyte protein 4, ipilimumab-VH, ipilimumab-VL | | Authors: | He, M, Chai, Y, Qi, J, Tong, Z, Tan, S, Gao, G.F. | | Deposit date: | 2017-04-29 | | Release date: | 2018-04-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies
Oncotarget, 8, 2017
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4G9I
 | | Crystal structure of T.kodakarensis HypF | | Descriptor: | Hydrogenase maturation protein HypF, ZINC ION | | Authors: | Tominaga, T, Watanabe, S, Matsumi, R, Atomi, H, Imanaka, T, Miki, K. | | Deposit date: | 2012-07-24 | | Release date: | 2012-10-24 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Structure of the [NiFe]-hydrogenase maturation protein HypF from Thermococcus kodakarensis KOD1.
Acta Crystallogr.,Sect.F, 68, 2012
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3VND
 | | Crystal structure of tryptophan synthase alpha-subunit from the psychrophile Shewanella frigidimarina K14-2 | | Descriptor: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SULFATE ION, Tryptophan synthase alpha chain | | Authors: | Mitsuya, D, Tanaka, S, Matsumura, H, Takano, K, Urano, N, Ishida, M. | | Deposit date: | 2012-01-12 | | Release date: | 2013-01-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Strategy for cold adaptation of the tryptophan synthase alpha subunit from the psychrophile Shewanella frigidimarina K14-2: crystal structure and physicochemical properties
J.Biochem., 155, 2014
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8YTI
 | | Crystal Structure of Nucleosome-H1x Linker Histone Assembly (sticky-169a DNA fragment) | | Descriptor: | CALCIUM ION, CHLORIDE ION, DNA (169-MER), ... | | Authors: | Adhireksan, Z, Qiuye, B, Padavattan, S, Davey, C.A. | | Deposit date: | 2024-03-26 | | Release date: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Linker Histones Associate Heterogeneously with Nucleosomes in the Condensed State
To Be Published
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5GRJ
 | | Crystal structure of human PD-L1 with monoclonal antibody avelumab | | Descriptor: | Programmed cell death 1 ligand 1, avelumab H chain, avelumab L chain | | Authors: | Liu, K, Tan, S, Chai, Y, Chen, D, Song, H, Zhang, C.W.-H, Shi, Y, Liu, J, Tan, W, Lyu, J, Gao, S, Yan, J, Qi, J, Gao, G.F. | | Deposit date: | 2016-08-11 | | Release date: | 2016-11-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.206 Å) | | Cite: | Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy.
Cell Res., 27, 2017
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8G57
 | | Structure of nucleosome-bound Sirtuin 6 deacetylase | | Descriptor: | DNA strand 1, DNA strand 2, Histone H2A type 1-B/E, ... | | Authors: | Chio, U.S, Rechiche, O, Bryll, A.R, Zhu, J, Feldman, J.L, Peterson, C.L, Tan, S, Armache, J.-P. | | Deposit date: | 2023-02-11 | | Release date: | 2023-04-26 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Cryo-EM structure of the human Sirtuin 6-nucleosome complex.
Sci Adv, 9, 2023
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8GVB
 | | The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 peptide | | Descriptor: | 8-mer peptide from Protein Nef, Beta-2-microglobulin, MHC class I antigen, ... | | Authors: | Gao, G.F, Shi, Y, Ma, K, Chai, Y, Guan, J, Qi, J, Tan, S, Dong, T, Iwamoto, A, Kawana-Tachikawa, A. | | Deposit date: | 2022-09-14 | | Release date: | 2022-10-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors.
J Immunol., 209, 2022
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8GVI
 | | The complex between H25-11 TCR and HLA-A24 bound to HIV-1 Nef138-8 peptide | | Descriptor: | 8-mer peptide from Protein Nef, Beta-2-microglobulin, H25-11 TCR alpha chain, ... | | Authors: | Gao, G.F, Shi, Y, Tan, S, Ma, K, Chai, Y, Qi, J, Kawana-Tachikawa, A, Iwamoto, A, Dong, T, Guan, J. | | Deposit date: | 2022-09-15 | | Release date: | 2022-10-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors.
J Immunol., 209, 2022
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8GVG
 | | The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 (2F) peptide | | Descriptor: | Beta-2-microglobulin, MHC class I antigen, TD08 TCR alpha chain, ... | | Authors: | Gao, G.F, Shi, Y, Ma, K, Chai, Y, Guan, J, Qi, J, Tan, S, Dong, T, Iwamoto, A, Kawana-Tachikawa, A. | | Deposit date: | 2022-09-15 | | Release date: | 2022-10-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.37 Å) | | Cite: | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors.
J Immunol., 209, 2022
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4HX1
 | | Structure of HLA-A68 complexed with a tumor antigen derived peptide | | Descriptor: | 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ... | | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2012-11-09 | | Release date: | 2013-10-02 | | Method: | X-RAY DIFFRACTION (1.802 Å) | | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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4HWZ
 | | Structure of HLA-A68 complexed with an HIV derived peptide | | Descriptor: | 9-mer peptide from Pol protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2012-11-09 | | Release date: | 2013-10-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.397 Å) | | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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4I48
 | | Structure of HLA-A68 complexed with an HIV Env derived peptide | | Descriptor: | 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | Authors: | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | Deposit date: | 2012-11-27 | | Release date: | 2013-10-02 | | Method: | X-RAY DIFFRACTION (2.799 Å) | | Cite: | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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