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8G9X
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BU of 8g9x by Molmil
Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Changela, A, Gorman, J, Kwong, P.D.
Deposit date:2023-02-22
Release date:2023-04-19
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.46 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
6TYB
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BU of 6tyb by Molmil
Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-08-08
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields.
Immunity, 51, 2019
8GAS
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BU of 8gas by Molmil
vFP48.02 Fab in complex with BG505 DS-SOSIP Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2023-02-23
Release date:2023-04-19
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
8G85
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BU of 8g85 by Molmil
vFP52.02 Fab in complex with BG505 DS-SOSIP Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2023-02-17
Release date:2023-04-19
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
8G9W
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BU of 8g9w by Molmil
Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Changela, A, Gorman, J, Kwong, P.D.
Deposit date:2023-02-22
Release date:2023-04-19
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.66 Å)
Cite:Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
6VFJ
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BU of 6vfj by Molmil
De novo designed icosahedral nanoparticle I53_dn5
Descriptor: I53_dn5A, I53_dn5B
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2020-01-05
Release date:2020-08-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.35 Å)
Cite:Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFH
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BU of 6vfh by Molmil
De novo designed tetrahedral nanoparticle T33_dn10
Descriptor: T33_dn10A, T33_dn10B
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2020-01-05
Release date:2020-08-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VFI
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BU of 6vfi by Molmil
De novo designed octahedral nanoparticle O43_dn18
Descriptor: O43_dn18A, O43_dn18B
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2020-01-05
Release date:2020-08-12
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (4.54 Å)
Cite:Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6V8E
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BU of 6v8e by Molmil
Computationally designed C3-symmetric homotrimer from TPR repeat protein
Descriptor: Designed protein
Authors:Sankaran, B, Ueda, G, Zwart, P.H, Baker, D.
Deposit date:2019-12-10
Release date:2020-08-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6VEH
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BU of 6veh by Molmil
Computationally designed C3-symmetric homotrimer from HEAT repeat protein
Descriptor: HEAT repeat domain-containing protein
Authors:Bick, M.J, Ueda, G, Baker, D.
Deposit date:2020-01-02
Release date:2020-08-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens.
Elife, 9, 2020
6XSK
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BU of 6xsk by Molmil
Cryo-EM Structure of Vaccine-Elicited Rhesus Antibody 789-203-3C12 in Complex with Stabilized SI06 (A/Solomon Islands/3/06) Influenza Hemagglutinin Trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 789-203-3C12 Fab Heavy Chain, ...
Authors:Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L.
Deposit date:2020-07-15
Release date:2021-07-21
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.
Immunity, 55, 2022
8F7T
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BU of 8f7t by Molmil
Glycan-Base ConC Env Trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env gp120, ...
Authors:Olia, A.S, Kwong, P.D.
Deposit date:2022-11-20
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases.
Iscience, 26, 2023
8DEC
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BU of 8dec by Molmil
Cryo-EM Structure of Western Equine Encephalitis Virus
Descriptor: Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2
Authors:Pletnev, S, Verardi, R, Roedeger, M, Kwong, P.
Deposit date:2022-06-20
Release date:2023-07-05
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8DEE
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BU of 8dee by Molmil
Asymmetric Unit of Western Equine Encephalitis Virus
Descriptor: Capsid protein, Spike glycoprotein E1, Spike glycoprotein E2
Authors:Pletnev, S, Verardi, R, Roedeger, M, Kwong, P.
Deposit date:2022-06-20
Release date:2023-07-05
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8DUA
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BU of 8dua by Molmil
SIV E660.CR54 SOS-2P Env Trimer with ITS92.02
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Envelope glycoprotein gp41, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2022-07-27
Release date:2022-10-26
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (4.32 Å)
Cite:Cryo-EM structures of prefusion SIV envelope trimer.
Nat.Struct.Mol.Biol., 29, 2022
8DVD
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BU of 8dvd by Molmil
Cryo-EM structure of SIVmac239 SOS-2P Env trimer in complex with human bNAb PGT145
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2022-07-28
Release date:2022-11-16
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (4.12 Å)
Cite:Cryo-EM structures of prefusion SIV envelope trimer.
Nat.Struct.Mol.Biol., 29, 2022
8DUL
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BU of 8dul by Molmil
Cryo-EM Structure of Antibody SKT05 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab SKT05 heavy chain, ...
Authors:Cerutti, G, Verardi, R, Roederer, M, Shapiro, L.
Deposit date:2022-07-27
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8DUN
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BU of 8dun by Molmil
Cryo-EM Structure of Antibody SKW11 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody SKW11 heavy chain, ...
Authors:Cerutti, G, Verardi, R, Roederer, M, Shapiro, L.
Deposit date:2022-07-27
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (5.84 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8DWO
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BU of 8dwo by Molmil
Cryo-EM Structure of Eastern Equine Encephalitis Virus in complex with SKE26 Fab
Descriptor: Envelope glycoprotein E1, Envelope glycoprotein E2, SKE26 Fab Heavy Chain, ...
Authors:Pletnev, S, Verardi, R, Roedeger, M, Kwong, P.
Deposit date:2022-08-01
Release date:2023-07-19
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8DER
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BU of 8der by Molmil
Cryo-EM local refinement of antibody SKV16 in complex with VEEV alphavirus spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SKV16 Fab Heavy Chain, ...
Authors:Casner, R.G, Verardi, R, Roederer, M, Shapiro, L.
Deposit date:2022-06-21
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
8DEQ
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BU of 8deq by Molmil
Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SKV09 Fab Heavy Chain, SKV09 Fab Light Chain, ...
Authors:Casner, R.G, Verardi, R, Roederer, M, Shapiro, L.
Deposit date:2022-06-21
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
7MY2
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BU of 7my2 by Molmil
CryoEM structure of neutralizing nanobody Nb30 in complex with SARS-CoV2 spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb30, ...
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-05-20
Release date:2021-06-16
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.
Nature, 595, 2021
7MY3
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BU of 7my3 by Molmil
CryoEM structure of neutralizing nanobody Nb12 in complex with SARS-CoV2 spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody Nb12, ...
Authors:Xu, K, Kwong, P.D.
Deposit date:2021-05-20
Release date:2021-06-16
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants.
Nature, 595, 2021
7TCQ
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BU of 7tcq by Molmil
Crystal structure of SARS-CoV-2 neutralizing antibody WS6 in complex with spike S2 peptide
Descriptor: Anti-SARS-CoV-2 antibody WS6 Fab heavy chain, Anti-SARS-CoV-2 antibody WS6 Fab light chain, DI(HYDROXYETHYL)ETHER, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2021-12-28
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability.
Structure, 30, 2022
7LZE
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BU of 7lze by Molmil
Cryo-EM Structure of disulfide stabilized HMPV F v4-B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Gorman, J, Kwong, P.D.
Deposit date:2021-03-09
Release date:2021-08-25
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Interprotomer disulfide-stabilized variants of the human metapneumovirus fusion glycoprotein induce high titer-neutralizing responses.
Proc.Natl.Acad.Sci.USA, 118, 2021

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