2GKJ
 
 | | Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor DL-AZIDAP | | Descriptor: | (2R,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID, ACETIC ACID, Diaminopimelate epimerase | | Authors: | Pillai, B, Cherney, M.M, Diaper, C.M, Sutherland, A, Blanchard, J.S, Vederas, J.C, James, M.N. | | Deposit date: | 2006-04-02 | | Release date: | 2006-05-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target.
Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2I6U
 | | Crystal Structure of Ornithine Carbamoyltransferase complexed with Carbamoyl Phosphate and L-Norvaline from Mycobacterium tuberculosis (Rv1656) at 2.2 A | | Descriptor: | NORVALINE, Ornithine carbamoyltransferase, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... | | Authors: | Sankaranarayanan, R, Moradian, F, Cherney, L.T, Garen, C, Cherney, M.M, James, M.N.G, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2006-08-29 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism
J.Mol.Biol., 375, 2008
|
|
1Y0H
 | | Structure of Rv0793 from Mycobacterium tuberculosis | | Descriptor: | ACETATE ION, hypothetical protein Rv0793 | | Authors: | Lemieux, M.J, Ference, C, Cherney, M.M, Wang, M, Garen, C, James, M.N, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2004-11-15 | | Release date: | 2004-12-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The crystal structure of Rv0793, a hypothetical monooxygenase from M. tuberculosis
J.STRUCT.FUNCT.GENOM., 6, 2005
|
|
1Y30
 | | X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with flavin mononucleotide at 2.2 a resolution | | Descriptor: | FLAVIN MONONUCLEOTIDE, hypothetical protein Rv1155 | | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Garen, C, James, M.N, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2004-11-23 | | Release date: | 2005-08-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate.
Acta Crystallogr.,Sect.D, 61, 2005
|
|
2HRV
 | | 2A CYSTEINE PROTEINASE FROM HUMAN RHINOVIRUS 2 | | Descriptor: | 2A CYSTEINE PROTEINASE, ZINC ION | | Authors: | Petersen, J.F.W, Cherney, M.M, Liebig, H.-D, Skern, T, Kuechler, E, James, M.N.G. | | Deposit date: | 1999-04-29 | | Release date: | 2000-05-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis.
EMBO J., 18, 1999
|
|
2AQ6
 | | X-ray crystal structure of mycobacterium tuberculosis pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 1.7 a resolution | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, PYRIDOXINE 5'-PHOSPHATE OXIDASE | | Authors: | Biswal, B.K, Cherney, M.M, Wang, M, Garen, C, James, M.N, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2005-08-17 | | Release date: | 2005-08-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate.
Acta Crystallogr.,Sect.D, 61, 2005
|
|
2ASF
 | | Crystal structure of the conserved hypothetical protein Rv2074 from Mycobacterium tuberculosis 1.6 A | | Descriptor: | CITRIC ACID, Hypothetical protein Rv2074, SODIUM ION | | Authors: | Biswal, B.K, Au, K, Cherney, M.M, Garen, C, James, M.N, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2005-08-23 | | Release date: | 2005-10-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The molecular structure of Rv2074, a probable pyridoxine 5'-phosphate oxidase from Mycobacterium tuberculosis, at 1.6 angstroms resolution.
Acta Crystallogr.,Sect.F, 62, 2006
|
|
2BCD
 | | X-ray crystal structure of Protein Phosphatase-1 with the marine toxin motuporin bound | | Descriptor: | BETA-MERCAPTOETHANOL, MANGANESE (II) ION, MOTUPORIN, ... | | Authors: | Maynes, J.T, Luu, H.A, Cherney, M.M, Andersen, R.J, Williams, D, Holmes, C.F, James, M.N. | | Deposit date: | 2005-10-19 | | Release date: | 2006-01-17 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structures of Protein Phosphatase-1 Bound to Motuporin and Dihydromicrocystin-LA: Elucidation of the Mechanism of Enzyme Inhibition by Cyanobacterial Toxins.
J.Mol.Biol., 356, 2006
|
|
2BDX
 | | X-ray Crystal Structure of dihydromicrocystin-LA bound to Protein Phosphatase-1 | | Descriptor: | DIHYDROMICROCYSTIN-LA, MANGANESE (II) ION, Serine/threonine protein phosphatase PP1-gamma catalytic subunit | | Authors: | Maynes, J.T, Luu, H.A, Cherney, M.M, Andersen, R.J, Williams, D, Holmes, C.F, James, M.N. | | Deposit date: | 2005-10-21 | | Release date: | 2006-01-17 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structures of Protein Phosphatase-1 Bound to Motuporin and Dihydromicrocystin-LA: Elucidation of the Mechanism of Enzyme Inhibition by Cyanobacterial Toxins.
J.Mol.Biol., 356, 2006
|
|
2GK1
 | | X-ray crystal structure of NGT-bound HexA | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, Beta-hexosaminidase subunit alpha, ... | | Authors: | Lemieux, M.J, Mark, B.L, Cherney, M.M, Withers, S.G, Mahuran, D.J, James, M.N. | | Deposit date: | 2006-03-31 | | Release date: | 2006-05-30 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Crystallographic Structure of Human beta-Hexosaminidase A: Interpretation of Tay-Sachs Mutations and Loss of G(M2) Ganglioside Hydrolysis.
J.Mol.Biol., 359, 2006
|
|
2GKE
 | | Crystal structure of diaminopimelate epimerase in complex with an irreversible inhibitor LL-AziDAP | | Descriptor: | (2S,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID, ACETIC ACID, Diaminopimelate epimerase, ... | | Authors: | Pillai, B, Cherney, M.M, Diaper, C.M, Sutherland, A, Blanchard, J.S, Vederas, J.C, James, M.N. | | Deposit date: | 2006-04-01 | | Release date: | 2006-05-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target.
Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
1KHV
 | | Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Lu3+ | | Descriptor: | LUTETIUM (III) ION, RNA-DIRECTED RNA POLYMERASE | | Authors: | Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. | | Deposit date: | 2001-12-01 | | Release date: | 2002-01-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase.
J.Biol.Chem., 277, 2002
|
|
1KHW
 | | Crystal Structure of Rabbit Hemorrhagic Disease Virus RNA-dependent RNA polymerase complexed with Mn2+ | | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | | Authors: | Ng, K.K, Cherney, M.M, Vazquez, A.L, Machin, A, Alonso, J.M, Parra, F, James, M.N. | | Deposit date: | 2001-12-01 | | Release date: | 2002-01-16 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase.
J.Biol.Chem., 277, 2002
|
|
1YU6
 | | Crystal Structure of the Subtilisin Carlsberg:OMTKY3 Complex | | Descriptor: | CALCIUM ION, Ovomucoid, Subtilisin Carlsberg | | Authors: | Maynes, J.T, Cherney, M.M, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | Deposit date: | 2005-02-11 | | Release date: | 2005-05-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations.
Acta Crystallogr.,Sect.D, 61, 2005
|
|
2ATO
 | | Crystal structure of Human Cathepsin K in complex with myocrisin | | Descriptor: | (S)-(1,2-DICARBOXYETHYLTHIO)GOLD, Cathepsin K, SULFATE ION | | Authors: | Weidauer, E, Yasuda, Y, Biswal, B.K, Kerr, L.D, Cherney, M.M, Gordon, R.E, James, M.N.G, Bromme, D. | | Deposit date: | 2005-08-25 | | Release date: | 2006-08-29 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Effects of disease-modifying anti-rheumatic drugs (DMARDs) on the activities of rheumatoid arthritis-associated cathepsins K and S.
Biol.Chem., 388, 2007
|
|
2GKR
 | | Crystal structure of the N-terminally truncated OMTKY3-del(1-5) | | Descriptor: | CHLORIDE ION, Ovomucoid | | Authors: | Lee, T.W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | Deposit date: | 2006-04-03 | | Release date: | 2007-02-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.16 Å) | | Cite: | Structural Insights into the Non-additivity Effects in the Sequence-to-Reactivity Algorithm for Serine Peptidases and their Inhibitors.
J.Mol.Biol., 367, 2007
|
|
2GKT
 | |
2GKV
 | | Crystal structure of the SGPB:P14'-Ala32 OMTKY3-del(1-5) complex | | Descriptor: | Ovomucoid, Streptogrisin B | | Authors: | Lee, T.W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | Deposit date: | 2006-04-03 | | Release date: | 2007-02-13 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Insights into the Non-additivity Effects in the Sequence-to-Reactivity Algorithm for Serine Peptidases and their Inhibitors.
J.Mol.Biol., 367, 2007
|
|
3ERE
 | | Crystal structure of the arginine repressor protein from Mycobacterium tuberculosis in complex with the DNA operator | | Descriptor: | 5'-D(*DTP*DTP*DGP*DCP*DAP*DTP*DAP*DAP*DCP*DGP*DAP*DTP*DGP*DCP*DAP*DA)-3', 5'-D(*DTP*DTP*DGP*DCP*DAP*DTP*DCP*DGP*DTP*DTP*DAP*DTP*DGP*DCP*DAP*DA)-3', Arginine repressor, ... | | Authors: | Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-10-01 | | Release date: | 2008-10-14 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the arginine repressor protein in complex with the DNA operator from Mycobacterium tuberculosis.
J.Mol.Biol., 384, 2008
|
|
1F32
 | | CRYSTAL STRUCTURE OF ASCARIS PEPSIN INHIBITOR-3 | | Descriptor: | MAJOR PEPSIN INHIBITOR PI-3 | | Authors: | Ng, K.K, Petersen, J.F, Cherney, M.M, Garen, C, James, M.N. | | Deposit date: | 2000-05-31 | | Release date: | 2001-02-01 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis for the inhibition of porcine pepsin by Ascaris pepsin inhibitor-3.
Nat.Struct.Biol., 7, 2000
|
|
1F34
 | | CRYSTAL STRUCTURE OF ASCARIS PEPSIN INHIBITOR-3 BOUND TO PORCINE PEPSIN | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAJOR PEPSIN INHIBITOR PI-3, PEPSIN A | | Authors: | Ng, K.K, Petersen, J.F, Cherney, M.M, Garen, C, James, M.N. | | Deposit date: | 2000-05-31 | | Release date: | 2001-02-01 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural basis for the inhibition of porcine pepsin by Ascaris pepsin inhibitor-3.
Nat.Struct.Biol., 7, 2000
|
|
3EI8
 | | Crystal structure of K270N variant of LL-diaminopimelate aminotransferase from Arabidopsis thaliana complexed with LL-DAP: External aldimine form | | Descriptor: | (2S,6S)-2-amino-6-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}heptanedioic acid, GLYCEROL, LL-diaminopimelate aminotransferase, ... | | Authors: | Watanabe, N, Clay, M.D, van Belkum, M.J, Cherney, M.M, Vederas, J.C, James, M.N.G. | | Deposit date: | 2008-09-15 | | Release date: | 2008-10-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
J.Mol.Biol., 384, 2008
|
|
3EIB
 | | Crystal structure of K270N variant of LL-diaminopimelate aminotransferase from Arabidopsis thaliana | | Descriptor: | GLYCEROL, LL-diaminopimelate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Watanabe, N, Clay, M.D, van Belkum, M.J, Cherney, M.M, Vederas, J.C, James, M.N.G. | | Deposit date: | 2008-09-15 | | Release date: | 2008-10-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
J.Mol.Biol., 384, 2008
|
|
3EI6
 | | Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana complexed with PLP-DAP: an external aldimine mimic | | Descriptor: | (2S,6S)-2-amino-6-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]heptanedioic acid, GLYCEROL, LL-diaminopimelate aminotransferase, ... | | Authors: | Watanabe, N, Clay, M.D, van Belkum, M.J, Cherney, M.M, Vederas, J.C, James, M.N.G. | | Deposit date: | 2008-09-15 | | Release date: | 2008-10-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
J.Mol.Biol., 384, 2008
|
|
3EKM
 | | Crystal structure of diaminopimelate epimerase form arabidopsis thaliana in complex with irreversible inhibitor DL-AziDAP | | Descriptor: | (2R,6S)-2,6-DIAMINO-2-METHYLHEPTANEDIOIC ACID, Diaminopimelate epimerase, chloroplastic | | Authors: | Pillai, B, Moorthie, V.A, Cherney, M.M, van Belkum, M.J, Vederas, J.C, James, M.N.G. | | Deposit date: | 2008-09-19 | | Release date: | 2009-02-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana, an amino acid racemase critical for L-lysine biosynthesis.
J.Mol.Biol., 385, 2009
|
|
