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8F53
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BU of 8f53 by Molmil
Top-down design of protein architectures with reinforcement learning
Descriptor: RC_I_2
Authors:Borst, A.J, Baker, D.
Deposit date:2022-11-11
Release date:2023-05-10
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
1LPL
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BU of 1lpl by Molmil
Structural Genomics of Caenorhabditis elegans: CAP-Gly domain of F53F4.3
Descriptor: Hypothetical 25.4 kDa protein F53F4.3 in chromosome V
Authors:Li, S, Finley, J, Liu, Z.-J, Qiu, S.H, Luan, C.H, Carson, M, Tsao, J, Johnson, D, Lin, G, Zhao, J, Thomas, W, Nagy, L.A, Sha, B, DeLucas, L.J, Wang, B.-C, Luo, M, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2002-05-08
Release date:2002-05-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal Structure of the Cytoskeleton-associated Protein Glycine-rich (CAP-Gly) Domain
J.Biol.Chem., 277, 2002
1L3B
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BU of 1l3b by Molmil
MT0146, THE PRECORRIN-6Y METHYLTRANSFERASE (CBIT) HOMOLOG FROM M. THERMOAUTOTROPHICUM, C2 SPACEGROUP W/ LONG CELL
Descriptor: Precorrin-6y methyltransferase/putative decarboxylase
Authors:Keller, J.P, Smith, P.M, Benach, J, Christendat, D, deTitta, G, Hunt, J.F.
Deposit date:2002-02-26
Release date:2002-11-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The Crystal Structure of Mt0146/CbiT Suggests that the Putative Precorrin-8W Decarboxylase is a Methyltransferase
Structure, 10, 2002
4TM9
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BU of 4tm9 by Molmil
Crystal Structure of Human Transthyretin Thr119Trp Mutant
Descriptor: Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-31
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
1LTR
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BU of 1ltr by Molmil
CRYSTAL STRUCTURE OF THE B SUBUNIT OF HUMAN HEAT-LABILE ENTEROTOXIN FROM E. COLI CARRYING A PEPTIDE WITH ANTI-HSV ACTIVITY
Descriptor: HEAT-LABILE ENTEROTOXIN, SULFATE ION
Authors:Matkovic-Calogovic, D, Loreggian, A, Palu, G, Zanotti, G.
Deposit date:1998-07-31
Release date:1999-02-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Crystal structure of the B subunit of Escherichia coli heat-labile enterotoxin carrying peptides with anti-herpes simplex virus type 1 activity.
J.Biol.Chem., 274, 1999
4TQA
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BU of 4tqa by Molmil
Crystal Structure of a GDP-bound G13D Oncogenic Mutant of Human GTPase KRas
Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Hunter, J.C, Manandhar, A, Gurbani, D, Chen, Z, Westover, K.D.
Deposit date:2014-06-10
Release date:2015-06-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations.
Mol Cancer Res., 13, 2015
1LB4
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BU of 1lb4 by Molmil
TRAF6 apo structure
Descriptor: TNF receptor-associated factor 6
Authors:Ye, H, Arron, J.R, Lamothe, B, Cirilli, M, Kobayashi, T, Shevde, N.K, Segal, D, Dzivenu, O, Vologodskaia, M, Yim, M, Du, K, Singh, S, Pike, J.W, Darnay, B.G, Choi, Y, Wu, H.
Deposit date:2002-04-02
Release date:2002-07-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Distinct molecular mechanism for initiating TRAF6 signalling.
Nature, 418, 2002
1LB5
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BU of 1lb5 by Molmil
TRAF6-RANK Complex
Descriptor: TNF receptor-associated factor 6, receptor activator of nuclear factor-kappa B
Authors:Ye, H, Arron, J.R, Lamothe, B, Cirilli, M, Kobayashi, T, Shevde, N.K, Segal, D, Dzivenu, O, Vologodskaia, M, Yim, M, Du, K, Singh, S, Pike, J.W, Darnay, B.G, Choi, Y, Wu, H.
Deposit date:2002-04-02
Release date:2002-07-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Distinct molecular mechanism for initiating TRAF6 signalling.
Nature, 418, 2002
1LF0
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BU of 1lf0 by Molmil
Crystal Structure of RasA59G in the GTP-bound form
Descriptor: CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Hall, B.E, Bar-Sagi, D, Nassar, N.
Deposit date:2002-04-10
Release date:2002-11-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structural Basis for the Transition from Ras-GTP to Ras-GDP
Proc.Natl.Acad.Sci.USA, 99, 2002
4RCA
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BU of 4rca by Molmil
Crystal structure of human PTPdelta and human Slitrk1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase delta, SLIT and NTRK-like protein 1, ...
Authors:Kim, H.M, Park, B.S, Kim, D, Lee, S.G.
Deposit date:2014-09-15
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9908 Å)
Cite:Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.
Nat Commun, 5, 2014
5W3S
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BU of 5w3s by Molmil
Cryo-electron microscopy structure of a TRPML3 ion channel
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL HEMISUCCINATE, Mucolipin-3 isoform 1, ...
Authors:Hirschi, M, Herzik, M.A, Wie, J, Suo, Y, Borschel, W.F, Ren, D, Lander, G.C, Lee, S.Y.
Deposit date:2017-06-08
Release date:2017-10-11
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.
Nature, 550, 2017
5W51
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BU of 5w51 by Molmil
Pol II elongation complex with an N6-methyladenine-containing template and a matched UMPNPP
Descriptor: 14mer non-template DNA, 29mer template DNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ...
Authors:Wang, W, Wang, D.
Deposit date:2017-06-13
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.404 Å)
Cite:Epigenetic DNA Modification N6-Methyladenine Causes Site-Specific RNA Polymerase II Transcriptional Pausing.
J.Am.Chem.Soc., 139, 2017
1LM6
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BU of 1lm6 by Molmil
Crystal Structure of Peptide Deformylase from Streptococcus pneumoniae
Descriptor: FE (III) ION, GLYCEROL, peptide deformylase DEFB
Authors:Kreusch, A, Spraggon, G, Lee, C.C, Klock, H, McMullan, D, Ng, K, Shin, T, Vincent, J, Warner, I, Ericson, C, Lesley, S.A.
Deposit date:2002-04-30
Release date:2003-06-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
5W6M
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BU of 5w6m by Molmil
Crystal structure of the human histidyl-tRNA synthetase mutant D175E
Descriptor: Histidine--tRNA ligase, cytoplasmic
Authors:Blocquel, D, Yang, X.L.
Deposit date:2017-06-16
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.696 Å)
Cite:CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells.
Proc.Natl.Acad.Sci.USA, 2019
5W3W
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BU of 5w3w by Molmil
Crystal structure of SsoPox AsD6 mutant (V27A-Y97W-L228M-W263M) - open form
Descriptor: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ...
Authors:Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M.
Deposit date:2017-06-08
Release date:2018-01-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase.
Sci Rep, 7, 2017
4OUN
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BU of 4oun by Molmil
Crystal Structure of Mini-ribonuclease 3 from Bacillus subtilis
Descriptor: Mini-ribonuclease 3
Authors:Chojnowski, G, Czarnecka, J, Nowak, E, Pianka, D, Glow, D, Sabala, I, Skowronek, K, Nowotny, M, Bujnicki, J.M.
Deposit date:2014-02-18
Release date:2015-02-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Sequence-specific cleavage of dsRNA by Mini-III RNase
Nucleic Acids Res., 43, 2015
1M1B
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BU of 1m1b by Molmil
Crystal Structure of Phosphoenolpyruvate Mutase Complexed with Sulfopyruvate
Descriptor: MAGNESIUM ION, PHOSPHOENOLPYRUVATE PHOSPHOMUTASE, SULFOPYRUVATE
Authors:Liu, S, Lu, Z, Jia, Y, Dunaway-Mariano, D, Herzberg, O.
Deposit date:2002-06-18
Release date:2002-08-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Dissociative phosphoryl transfer in PEP mutase catalysis: structure of the enzyme/sulfopyruvate complex and kinetic properties of mutants.
Biochemistry, 41, 2002
7S24
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BU of 7s24 by Molmil
Crystal structure of the Na+/H+ antiporter NhaA at pH 6.5
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Na(+)/H(+) antiporter NhaA, PENTAETHYLENE GLYCOL
Authors:Drew, D, Brock, J, Uzdavinys, P, Matsuoka, R.
Deposit date:2021-09-03
Release date:2022-08-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Na + /H + antiporter NhaA at active pH reveals the mechanistic basis for pH sensing.
Nat Commun, 13, 2022
1M4M
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BU of 1m4m by Molmil
Mouse Survivin
Descriptor: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, ZINC ION
Authors:Muchmore, S.W, Chen, J, Jakob, C, Zakula, D, Matayoshi, E.D, Wu, W, Zhang, H, Li, F, Ng, S.C, Altieri, D.C.
Deposit date:2002-07-03
Release date:2002-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:CRYSTAL STRUCTURE AND MUTAGENIC ANALYSIS OF THE INHIBITOR-OF-APOPTOSIS PROTEIN SURVIVIN
MOL.CELL, 6, 2000
7RXF
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BU of 7rxf by Molmil
Multi-conformer model of Apo Ketosteroid Isomerase Y57F mutant from Pseudomonas Putida (pKSI) at 250 K
Descriptor: CHLORIDE ION, MAGNESIUM ION, Steroid Delta-isomerase
Authors:Yabukarski, F, Doukov, T, Herschlag, D.
Deposit date:2021-08-23
Release date:2022-11-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Ensemble-function relationships to dissect mechanisms of enzyme catalysis.
Sci Adv, 8, 2022
1MN7
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BU of 1mn7 by Molmil
NDP kinase mutant (H122G;N119S;F64W) in complex with aBAZTTP
Descriptor: 3'-AZIDO-3'-DEOXY-THYMIDINE-5'-ALPHA BORANO TRIPHOSPHATE, MAGNESIUM ION, NDP kinase
Authors:gallois-montbrun, s, schneider, b, chen, y, giacomoni-fernandes, v, mulard, l, morera, s, janin, j, deville-bonne, d, veron, m.
Deposit date:2002-09-05
Release date:2002-10-02
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Improving nucleoside diphosphate kinase for antiviral nucleotide analogs activation
J.BIOL.CHEM., 277, 2002
7SEH
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BU of 7seh by Molmil
Glucose-6-phosphate 1-dehydrogenase (K403QdLtL)
Descriptor: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Mathews, I.I, Garcia, A.A, Wakatsuki, S, Mochly-Rosen, D.
Deposit date:2021-09-30
Release date:2022-08-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants.
J.Biol.Chem., 298, 2022
5TIC
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BU of 5tic by Molmil
X-ray structure of wild-type E. coli Acyl-CoA thioesterase I at pH 5
Descriptor: Acyl-CoA thioesterase I, CHLORIDE ION
Authors:Thoden, J.B, Holden, H.M, Grisewood, M.J, Hernandez Lozada, N.J, Gifford, N.P, Mendez-Perez, D, Schoenberger, H.A, Allan, M.F, Pfleger, B.F, Marines, C.D.
Deposit date:2016-10-02
Release date:2017-04-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Computational Redesign of Acyl-ACP Thioesterase with Improved Selectivity toward Medium-Chain-Length Fatty Acids.
ACS Catal, 7, 2017
1MGY
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BU of 1mgy by Molmil
Structure of the D85S mutant of bacteriorhodopsin with bromide bound
Descriptor: 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, BROMIDE ION, Bacteriorhodopsin, ...
Authors:Facciotti, M.T, Cheung, V.S, Nguyen, D, Rouhani, S, Glaeser, R.M.
Deposit date:2002-08-16
Release date:2003-07-07
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Bromide-Bound D85S Mutant of Bacteriorhodopsin: Principles of Ion Pumping
Biophys.J., 85, 2003
7RXK
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BU of 7rxk by Molmil
Multi-conformer model of Apo Ketosteroid Isomerase Y32F/Y57F mutant from Pseudomonas Putida (pKSI) at 250 K
Descriptor: CHLORIDE ION, MAGNESIUM ION, Steroid Delta-isomerase
Authors:Yabukarski, F, Doukov, T, Herschlag, D.
Deposit date:2021-08-23
Release date:2022-11-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Ensemble-function relationships to dissect mechanisms of enzyme catalysis.
Sci Adv, 8, 2022

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