8K8I
 
 | | De novo design protein -N14 | | Descriptor: | De novo design protein -N14 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-07-30 | | Release date: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | De novo design protein -N14
To Be Published
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8K83
 | | De novo design protein -N2 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, De novo design protein, GLYCEROL | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-07-28 | | Release date: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | De novo design protein -N2
To Be Published
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8K7Z
 | | De novo design protein -N1 | | Descriptor: | De novo design protein | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-07-27 | | Release date: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | De novo design protein -N1
To Be Published
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8K8G
 | | De novo design protein -N9 | | Descriptor: | De novo design protein | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-07-29 | | Release date: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | De novo design protein -N9
To Be Published
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8KC4
 | | De novo design protein -NA05 | | Descriptor: | De novo design protein -NA05 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-06 | | Release date: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | De novo design protein -NA05
To Be Published
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8K8F
 | | De novo design protein -N7 | | Descriptor: | De novo design protein N7, GLYCEROL | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-07-29 | | Release date: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | De novo design protein -N7
To Be Published
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8KA7
 | | De novo design protein -NB7 | | Descriptor: | De novo design protein -NB7 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-02 | | Release date: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | De novo design protein -NB7
To Be Published
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8K84
 | | De novo design protein -N3 | | Descriptor: | DI(HYDROXYETHYL)ETHER, De novo design protein | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-07-28 | | Release date: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | De novo design protein -N3
To Be Published
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8KC5
 | | De novo design protein -T09 | | Descriptor: | De novo design protein -T09 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-06 | | Release date: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | De novo design protein -T09
To Be Published
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8KA6
 | | De novo design protein -NA7 | | Descriptor: | De novo design protein -NA7 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-02 | | Release date: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | De novo design protein -NA7
To Be Published
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8KC8
 | | De novo design protein -T11 | | Descriptor: | De novo design protein -T11 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-06 | | Release date: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | De novo design protein -T11
To Be Published
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8KC1
 | | De novo design protein -NX5 | | Descriptor: | De novo design protein -NX5 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-05 | | Release date: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | De novo design protein -NX5
To Be Published
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8KCJ
 | | De novo design protein -N7 | | Descriptor: | De novo design protein -N7, GLYCEROL | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-07 | | Release date: | 2024-08-14 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | De novo design protein -N7
To Be Published
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8KCK
 | | De novo design protein -N9 | | Descriptor: | De novo design protein -N9 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-07 | | Release date: | 2024-08-14 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | De novo design protein -N9
To Be Published
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8KDQ
 | | De novo design protein -T03 | | Descriptor: | De novo design protein -T03 | | Authors: | Wang, S, Liu, Y. | | Deposit date: | 2023-08-09 | | Release date: | 2024-08-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | De novo design protein -T03
To Be Published
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5ZUE
 | | GTP-bound, double-stranded, curved FtsZ protofilament structure | | Descriptor: | Cell division protein FtsZ, GUANOSINE-5'-TRIPHOSPHATE | | Authors: | Guan, F, Yu, J, Yu, J, Liu, Y, Li, Y, Feng, X.H, Huang, K.C, Chang, Z, Ye, S. | | Deposit date: | 2018-05-07 | | Release date: | 2018-07-04 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Lateral interactions between protofilaments of the bacterial tubulin homolog FtsZ are essential for cell division
Elife, 7, 2018
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6B0V
 | | Crystal Structure of small molecule ARS-107 covalently bound to K-Ras G12C | | Descriptor: | 1-[3-(4-{[(4,5-dichloro-2-hydroxyphenyl)amino]acetyl}piperazin-1-yl)azetidin-1-yl]propan-1-one, CALCIUM ION, GTPase KRas, ... | | Authors: | Hansen, R, Peters, U, Babbar, A, Chen, Y, Feng, J, Janes, M.R, Li, L.-S, Ren, P, Liu, Y, Zarrinkar, P.P. | | Deposit date: | 2017-09-15 | | Release date: | 2018-05-16 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | The reactivity-driven biochemical mechanism of covalent KRASG12Cinhibitors.
Nat. Struct. Mol. Biol., 25, 2018
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8H2I
 | | Near-atomic structure of five-fold averaged PBCV-1 capsid | | Descriptor: | MCPv1, MCPv2, MCPv3, ... | | Authors: | Shao, Q, Agarkova, I.V, Noel, E.A, Dunigan, D.D, Liu, Y, Wang, A, Guo, M, Xie, L, Zhao, X, Rossmann, M.G, Van Etten, J.L, Klose, T, Fang, Q. | | Deposit date: | 2022-10-06 | | Release date: | 2022-11-16 | | Last modified: | 2023-09-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Near-atomic, non-icosahedrally averaged structure of giant virus Paramecium bursaria chlorella virus 1.
Nat Commun, 13, 2022
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6JWE
 | | structure of RET G-quadruplex in complex with colchicine | | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3'), N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide | | Authors: | Wang, F, Wang, C, Liu, Y, Lan, W.X, Li, Y.M, Wang, R.X, Cao, C. | | Deposit date: | 2019-04-20 | | Release date: | 2020-02-26 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR.
Chem.Commun.(Camb.), 56, 2020
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6JWD
 | | structure of RET G-quadruplex in complex with berberine | | Descriptor: | BERBERINE, DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3') | | Authors: | Wang, F, Wang, C, Liu, Y, Lan, W.X, Li, Y.M, Wang, R.X, Cao, C. | | Deposit date: | 2019-04-19 | | Release date: | 2020-04-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR.
Chem.Commun.(Camb.), 56, 2020
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7E29
 | | Crystal Structure of Saccharomyces cerevisiae Ioc4 PWWP domain fused with MBP | | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,ISWI one complex protein 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Li, J, Smolle, M, Liang, H, Liu, Y. | | Deposit date: | 2021-02-05 | | Release date: | 2022-02-09 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.303 Å) | | Cite: | H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function.
Nucleic Acids Res., 50, 2022
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8JIF
 | | Cryo-EM Structure of 3-axis block of AAV9P31-Car4 complex | | Descriptor: | Capsid protein VP1, Carbonic anhydrase 4, ZINC ION | | Authors: | Zhang, R, Liu, Y, Lou, Z. | | Deposit date: | 2023-05-26 | | Release date: | 2024-01-31 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.28 Å) | | Cite: | Structural basis of the recognition of adeno-associated virus by the neurological system-related receptor carbonic anhydrase IV.
Plos Pathog., 20, 2024
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8JZ7
 | | Cryo-EM structure of MK-6892-bound HCAR2 in complex with Gi protein | | Descriptor: | 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | Deposit date: | 2023-07-04 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2.
Signal Transduct Target Ther, 8, 2023
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8JIL
 | | Cryo-EM structure of niacin bound ketone body receptor HCAR2-Gi signaling complex | | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | Deposit date: | 2023-05-26 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
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8JII
 | | Cryo-EM structure of compound 9n and niacin bound ketone body receptor HCAR2-Gi signaling complex | | Descriptor: | 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | Deposit date: | 2023-05-26 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
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