3BW7
| |
1MDT
| |
2FEQ
| orally active thrombin inhibitors | Descriptor: | Decapeptide Hirudin Analogue, N-(CARBOXYMETHYL)-3-CYCLOHEXYL-D-ALANYL-N-({4-[(E)-AMINO(IMINO)METHYL]-1,3-THIAZOL-2-YL}METHYL)-L-PROLINAMIDE, Thrombin heavy chain, ... | Authors: | Mack, H, Baucke, D, Hornberger, W, Lange, U.E.W, Hoeffken, H.W. | Deposit date: | 2005-12-16 | Release date: | 2006-08-08 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Orally active thrombin inhibitors. Part 1: optimization of the P1-moiety Bioorg.Med.Chem.Lett., 16, 2006
|
|
2FGH
| ATP bound gelsolin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, gelsolin | Authors: | Ma, Q, Robinson, R.C, Burtnick, L.D, Urosev, D. | Deposit date: | 2005-12-22 | Release date: | 2006-04-18 | Last modified: | 2017-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structure of gelsolin bound to ATP J.Mol.Biol., 357, 2006
|
|
2F8H
| Structure of acetylcitrulline deacetylase from Xanthomonas campestris in metal-free form | Descriptor: | aectylcitrulline deacetylase | Authors: | Shi, D, Yu, X, Roth, L, Allewell, N.M, Tuchman, M. | Deposit date: | 2005-12-02 | Release date: | 2006-09-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of a novel N-acetyl-L-citrulline deacetylase from Xanthomonas campestris Biophys.Chem., 126, 2007
|
|
2F8V
| Structure of full length telethonin in complex with the N-terminus of titin | Descriptor: | N2B-Titin Isoform, SULFATE ION, Telethonin | Authors: | Pinotsis, N, Petoukhov, M, Lange, S, Svergun, D, Zou, P, Gautel, M, Wilmanns, M. | Deposit date: | 2005-12-04 | Release date: | 2006-06-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus. J.Struct.Biol., 155, 2006
|
|
3C0P
| |
2FH2
| C-terminal half of gelsolin soaked in EGTA at pH 4.5 | Descriptor: | CALCIUM ION, Gelsolin | Authors: | Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C. | Deposit date: | 2005-12-23 | Release date: | 2006-06-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Calcium ion exchange in crystalline gelsolin J.Mol.Biol., 357, 2006
|
|
2ERY
| The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein R-Ras2 | Authors: | Salah, E, Schoch, G, Turnbull, A, Papagrigoriou, E, Soundararajan, M, Burgess, N, Elkins, J, Gileadi, C, Gileadi, O, von Delft, F, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2005-10-25 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state To be Published
|
|
3C9J
| The Crystal structure of Transmembrane domain of M2 protein and Amantadine complex | Descriptor: | (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, Proton Channel protein M2, transmembrane segment | Authors: | Stouffer, A.L, Acharya, R, Salom, D. | Deposit date: | 2008-02-15 | Release date: | 2008-03-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for the function and inhibition of an influenza virus proton channel Nature, 451, 2008
|
|
1MZN
| CRYSTAL STRUCTURE at 1.9 ANGSTROEMS RESOLUTION OF THE HOMODIMER OF HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO THE SYNTHETIC AGONIST COMPOUND BMS 649 AND A COACTIVATOR PEPTIDE | Descriptor: | 4-[2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-[1,3]DIOXOLAN-2-YL]-BENZOIC ACID, Nuclear receptor coactivator 2, RXR retinoid X receptor | Authors: | Egea, P.F, Mitschler, A, Moras, D. | Deposit date: | 2002-10-09 | Release date: | 2002-10-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular Recognition of Agonist Ligands by RXRs MOL.ENDOCRINOL., 16, 2002
|
|
2EZT
| Pyruvate oxidase variant F479W in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate | Descriptor: | 2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... | Authors: | Wille, G, Meyer, D, Steinmetz, A, Hinze, E, Golbik, R, Tittmann, K. | Deposit date: | 2005-11-10 | Release date: | 2006-04-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography. Nat.Chem.Biol., 2, 2006
|
|
2LFU
| The structure of a N. meningitides protein targeted for vaccine development | Descriptor: | Gna2132 | Authors: | Esposito, V, Musi, V, De Chiara, C, Kelly, G, Veggi, D, Pizza, M, Pastore, A. | Deposit date: | 2011-07-15 | Release date: | 2011-10-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the C-terminal Domain of Neisseria Heparin Binding Antigen (NHBA), One of the Main Antigens of a Novel Vaccine against Neisseria meningitidis. J.Biol.Chem., 286, 2011
|
|
3C5Q
| Crystal structure of diaminopimelate decarboxylase (I148L mutant) from Helicobacter pylori complexed with L-lysine | Descriptor: | Diaminopimelate decarboxylase, GLYCEROL, LYSINE, ... | Authors: | Hu, T, Wu, D, Jiang, H, Shen, X. | Deposit date: | 2008-02-01 | Release date: | 2008-05-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of diaminopimelate decarboxylase from Helicobacter pylori To be Published
|
|
3NVF
| |
1ZYT
| Crystal structure of spin labeled T4 Lysozyme (A82R1) | Descriptor: | 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ... | Authors: | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | Deposit date: | 2005-06-10 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | EPR (1.7 Å), X-RAY DIFFRACTION | Cite: | Structural origin of weakly ordered nitroxide motion in spin-labeled proteins Protein Sci., 18, 2009
|
|
3NVG
| |
3NW9
| Rat COMT in complex with a methylpurin-containing bisubstrate inhibitor | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, Catechol O-methyltransferase, ... | Authors: | Ehler, A, Schlatter, D, Stihle, M, Benz, J, Rudolph, M.G. | Deposit date: | 2010-07-09 | Release date: | 2011-03-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular Recognition at the Active Site of Catechol-O-methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors Chemistry, 17, 2011
|
|
3C8A
| |
3BYI
| Crystal structure of human Rho GTPase activating protein 15 (ARHGAP15) | Descriptor: | Rho GTPase activating protein 15 | Authors: | Shrestha, L, Tickle, J, Elkins, J, Burgess-Brown, N, Johansson, C, Papagrigoriou, E, Kavanagh, K, Pike, A.C.W, Ugochukwu, E, Uppenberg, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Doyle, D, Structural Genomics Consortium (SGC) | Deposit date: | 2008-01-16 | Release date: | 2008-02-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structure of Human Rho GTPase Activating Protein 15 (ARHGAP15). To be Published
|
|
3C90
| The 1.25 A Resolution Structure of Phosphoribosyl-ATP Pyrophosphohydrolase from Mycobacterium tuberculosis, crystal form II | Descriptor: | Phosphoribosyl-ATP pyrophosphatase | Authors: | Javid-Majd, F, Yang, D, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2008-02-14 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 64, 2008
|
|
3BKD
| High resolution Crystal structure of Transmembrane domain of M2 protein | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Transmembrane Domain of Matrix protein M2, ... | Authors: | Stouffer, A.L, Acharya, R, Salom, D. | Deposit date: | 2007-12-06 | Release date: | 2008-01-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for the function and inhibition of an influenza virus proton channel Nature, 451, 2008
|
|
2ERX
| Crystal Structure of DiRas2 in Complex With GDP and Inorganic Phosphate | Descriptor: | GTP-binding protein Di-Ras2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Papagrigoriou, E, Yang, X, Elkins, J, Niesen, F.E, Burgess, N, Salah, E, Fedorov, O, Ball, L.J, von Delft, F, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D. | Deposit date: | 2005-10-25 | Release date: | 2005-11-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal Structure of DiRas2 To be Published
|
|
3C4S
| Crystal structure of the Ssl0352 protein from Synechocystis sp. Northeast Structural Genomics Consortium target SgR42 | Descriptor: | Ssl0352 protein | Authors: | Vorobiev, S.M, Chen, Y, Seetharaman, J, Wang, D, Maglaqui, M, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-01-30 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the Ssl0352 protein from Synechocystis sp. To be Published
|
|
3PNY
| |