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6FB1
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BU of 6fb1 by Molmil
Crystal Structure of a Tailored I-CreI Homing Endonuclease Protein (3115 variant) in complex with its target DNA (Haemoglobin beta subunit gene) in the presence of Magnesium
Descriptor: DNA (5'-D(*TP*CP*AP*GP*AP*CP*TP*TP*CP*TP*CP*CP*AP*C)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*CP*TP*CP*CP*TP*GP*TP*GP*G)-3'), DNA (5'-D(P*AP*GP*AP*AP*GP*TP*CP*TP*GP*A)-3'), ...
Authors:Molina, R, Prieto, J.
Deposit date:2017-12-18
Release date:2018-07-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.024 Å)
Cite:Understanding the indirect DNA read-out specificity of I-CreI Meganuclease.
Sci Rep, 8, 2018
6FB8
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BU of 6fb8 by Molmil
Crystal Structure of the I-CreI Homing Endonuclease D75N variant in complex with an altered version of its target DNA at 5NNN region in the presence of Magnesium
Descriptor: DNA (5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*CP*GP*CP*AP*GP*TP*TP*TP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*AP*AP*AP*CP*TP*GP*CP*GP*TP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3'), DNA endonuclease I-CreI, ...
Authors:Molina, R, Prieto, J.
Deposit date:2017-12-18
Release date:2018-07-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Understanding the indirect DNA read-out specificity of I-CreI Meganuclease.
Sci Rep, 8, 2018
6FB7
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BU of 6fb7 by Molmil
Crystal Structure of the I-CreI Homing Endonuclease D75N variant in complex with its target DNA in the presence of Manganese
Descriptor: DNA (5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*AP*CP*GP*TP*TP*TP*TP*GP*A)-3'), DNA endonuclease I-CreI, ...
Authors:Molina, R, Prieto, J.
Deposit date:2017-12-18
Release date:2018-07-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.689 Å)
Cite:Understanding the indirect DNA read-out specificity of I-CreI Meganuclease.
Sci Rep, 8, 2018
3MXA
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BU of 3mxa by Molmil
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Descriptor: DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(P*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ...
Authors:Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G.
Deposit date:2010-05-07
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
3MX9
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BU of 3mx9 by Molmil
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Descriptor: CALCIUM ION, DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ...
Authors:Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G.
Deposit date:2010-05-07
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
3MXB
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BU of 3mxb by Molmil
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Descriptor: CALCIUM ION, DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ...
Authors:Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G.
Deposit date:2010-05-07
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
Nucleic Acids Res., 39, 2011
4ZTD
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BU of 4ztd by Molmil
Crystal Structure of Human PCNA in complex with a TRAIP peptide
Descriptor: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen
Authors:Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A.
Deposit date:2015-05-14
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212, 2016
5ME8
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BU of 5me8 by Molmil
N-terminal domain of the human tumor suppressor ING5
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Inhibitor of growth protein 5
Authors:Roversi, P, Blanco, F.J, Rojas, A.L, Buitrago, J.A.R.
Deposit date:2016-11-14
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431, 2019
5MTO
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BU of 5mto by Molmil
N-terminal domain of the human tumor suppressor ING5 C19S mutant
Descriptor: Inhibitor of growth protein 5, SODIUM ION, SULFATE ION
Authors:Ormaza, G, Buitrago, J.A.R, Roversi, P, Rojas, A.L, Blanco, F.J.
Deposit date:2017-01-10
Release date:2018-02-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.
J.Mol.Biol., 431, 2019
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