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6XL1
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BU of 6xl1 by Molmil
crystal structure of cA4-activated Card1(D294N)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Card1, MANGANESE (II) ION, ...
Authors:Rostol, J, Xie, W, Patel, D.J, Marraffini, L.
Deposit date:2020-06-27
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Card1 nuclease provides defence during type III CRISPR immunity.
Nature, 590, 2021
1N49
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BU of 1n49 by Molmil
Viability of a Drug-Resistant HIV-1 Protease Variant: Structural Insights for Better Anti-Viral Therapy
Descriptor: Protease, RITONAVIR
Authors:Prabu-Jeyabalan, M, Nalivaika, E.A, King, N.M, Schiffer, C.A.
Deposit date:2002-10-30
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Viability of a Drug-Resistant Human Immunodeficiency Virus Type 1 Protease Variant: Structural Insights for Better Antiviral Therapy
J.VIROL., 77, 2003
4O33
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BU of 4o33 by Molmil
Crystal Structure of human PGK1 3PG and terazosin(TZN) ternary complex
Descriptor: 3-PHOSPHOGLYCERIC ACID, Phosphoglycerate kinase 1, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][(2R)-tetrahydrofuran-2-yl]methanone
Authors:Li, X.L, Finci, L.I, Wang, J.H.
Deposit date:2013-12-18
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Terazosin activates Pgk1 and Hsp90 to promote stress resistance.
Nat.Chem.Biol., 11, 2015
4O3F
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BU of 4o3f by Molmil
Crystal Structure of mouse PGK1 3PG and terazosin(TZN) ternary complex
Descriptor: 3-PHOSPHOGLYCERIC ACID, Phosphoglycerate kinase 1, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][(2R)-tetrahydrofuran-2-yl]methanone
Authors:Li, X.L, Finci, I.L, Wang, J.H.
Deposit date:2013-12-18
Release date:2014-10-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.106 Å)
Cite:Terazosin activates Pgk1 and Hsp90 to promote stress resistance.
Nat.Chem.Biol., 11, 2015
1PSU
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BU of 1psu by Molmil
Structure of the E. coli PaaI protein from the phyenylacetic acid degradation operon
Descriptor: Phenylacetic acid degradation protein PaaI
Authors:Kniewel, R, Buglino, J, Solorzano, V, Wu, J, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2003-06-21
Release date:2003-07-08
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure, function, and mechanism of the phenylacetate pathway hot dog-fold thioesterase PaaI.
J.Biol.Chem., 281, 2006
2FS2
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BU of 2fs2 by Molmil
Structure of the E. coli PaaI protein from the phyenylacetic acid degradation operon
Descriptor: Phenylacetic acid degradation protein paaI, SULFATE ION
Authors:Kniewel, R, Buglino, J.A, Solorzano, V, Wu, J, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-01-20
Release date:2006-02-07
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure, Function, and Mechanism of the Phenylacetate Pathway Hot Dog-fold Thioesterase PaaI
J.Biol.Chem., 281, 2006
5FUO
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BU of 5fuo by Molmil
Extending the half-life of a Fab fragment through generation of a humanised anti-Human Serum Albumin (HSA) Fv domain: an investigation into the correlation between affinity and serum half-life
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, SERUM ALBUMIN
Authors:Adams, R, Ceska, T.
Deposit date:2016-01-28
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Extending the Half-Life of a Fab Fragment Through Generation of a Humanized Anti-Human Serum Albumin Fv Domain: An Investigation Into the Correlation between Affinity and Serum Half-Life.
Mabs, 8, 2016
5FUZ
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BU of 5fuz by Molmil
Extending the half-life of a Fab fragment through generation of a humanised anti-Human Serum Albumin (HSA) Fv domain: an investigation into the correlation between affinity and serum half-life
Descriptor: 645 FAB, HEAVY CHAIN, LIGHT CHAIN
Authors:Adams, R, Ceska, T.
Deposit date:2016-02-01
Release date:2016-06-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Extending the Half-Life of a Fab Fragment Through Generation of a Humanized Anti-Human Serum Albumin Fv Domain: An Investigation Into the Correlation between Affinity and Serum Half-Life.
Mabs, 8, 2016
5F72
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BU of 5f72 by Molmil
De novo design and crystallographic validation of antibodies targeting a pre-selected epitope
Descriptor: Kelch-like ECH-associated protein 1, Single chain Fv from a Fab
Authors:Liu, X, Taylor, R.D, Griffin, L, Coker, S, Adams, R, Ceska, T, Shi, J, Lawson, A.D.G, Baker, T.
Deposit date:2015-12-07
Release date:2016-12-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:De novo design and crystallographic validation of antibodies targeting a pre-selected epitope
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