8JA0
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5GZL
| Cyclodeaminase_PA | 分子名称: | LYSINE, Lysine cyclodeaminase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Ying, H, Chen, K. | 登録日 | 2016-09-29 | 公開日 | 2018-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Cyclodeaminase_PA To Be Published
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5GZI
| Cyclodeaminase_PA | 分子名称: | (2S)-piperidine-2-carboxylic acid, Lysine cyclodeaminase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Ying, H, Chen, K. | 登録日 | 2016-09-28 | 公開日 | 2018-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Cyclodeaminase_PA To Be Published
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5GZJ
| Cyclodeaminase_PA | 分子名称: | Lysine cyclodeaminase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Ying, H, Chen, K. | 登録日 | 2016-09-28 | 公開日 | 2018-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Cyclodeaminase_PA To Be Published
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5GZM
| Cyclodeaminase_PA | 分子名称: | (2S)-piperidine-2-carboxylic acid, Lysine cyclodeaminase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Ying, H, Chen, K. | 登録日 | 2016-09-29 | 公開日 | 2018-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cyclodeaminase_PA To Be Published
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8IYS
| TUG891-bound FFAR4 in complex with Gq | 分子名称: | 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | He, Y, Yin, H. | 登録日 | 2023-04-06 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
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8H4I
| DHA-bound FFAR4 in complex with Gs | 分子名称: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | He, Y, Yin, H. | 登録日 | 2022-10-10 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
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8H4L
| DHA-bound FFAR4 in complex with Gq | 分子名称: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | He, Y, Yin, H. | 登録日 | 2022-10-10 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
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8H4K
| GW9508-bound FFAR4 in complex with Gq | 分子名称: | 3-(4-{[(3-phenoxyphenyl)methyl]amino}phenyl)propanoic acid, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | He, Y, Yin, H. | 登録日 | 2022-10-10 | 公開日 | 2023-06-21 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
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7WJQ
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5WSZ
| Crystal structure of a lytic polysaccharide monooxygenase,BtLPMO10A, from Bacillus thuringiensis | 分子名称: | COPPER (II) ION, LpmO10A | 著者 | Zhao, Y, Zhang, H, Yin, H. | 登録日 | 2016-12-08 | 公開日 | 2017-02-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.565 Å) | 主引用文献 | Crystal structure of a lytic polysaccharide monooxygenase,BtLPMO10A, from Bacillus thuringiensis To Be Published
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3RVG
| Crystals structure of Jak2 with a 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitor | 分子名称: | 1-(cyclohexylamino)-7-(1-methyl-1H-pyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide, Tyrosine-protein kinase JAK2 | 著者 | Lim, J, Taoka, B, Otte, R.D, Spencer, K, Dinsmore, C.J, Altman, M.D, Chan, G, Rosenstein, C, Sharma, S, Su, H.P, Szewczak, A.A, Xu, L, Yin, H, Zugay-Murphy, J, Marshall, C.G, Young, J.R. | 登録日 | 2011-05-06 | 公開日 | 2012-03-21 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | 主引用文献 | Discovery of 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitors of Janus kinase 2 (JAK2) for the treatment of myeloproliferative disorders. J.Med.Chem., 54, 2011
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7V8O
| Crystal structure of cyclohexanone monooxygenase from T. municipale mutant L437T complexed with NADP+ and FAD in space group of P21221 | 分子名称: | 1,2-ETHANEDIOL, Cyclohexanone Monooxygenase from Thermocrispum municipale, DI(HYDROXYETHYL)ETHER, ... | 著者 | Li, T, Li, G.Y, Yin, H. | 登録日 | 2021-08-23 | 公開日 | 2022-07-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Biocatalytic Baeyer-Villiger Reactions: Uncovering the Source of Regioselectivity at Each Evolutionary Stage of a Mutant with Scrutiny of Fleeting Chiral Intermediates. Acs Catalysis, 12, 2022
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7V8S
| Crystal structure of cyclohexanone monooxygenase from T. municipale mutant L437T complexed with NADP+ and FAD in space group of P1211 | 分子名称: | Cyclohexanone Monooxygenase from Thermocrispum municipale, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Li, T, Li, G.Y, Yin, H. | 登録日 | 2021-08-23 | 公開日 | 2022-07-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Biocatalytic Baeyer-Villiger Reactions: Uncovering the Source of Regioselectivity at Each Evolutionary Stage of a Mutant with Scrutiny of Fleeting Chiral Intermediates. Acs Catalysis, 12, 2022
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7V8R
| Crystal structure of cyclohexanone monooxygenase from T. municipale mutant L437T complexed with NADP+ and FAD in space group of C2221 | 分子名称: | 1,2-ETHANEDIOL, Cyclohexanone Monooxygenase from Thermocrispum municipale, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Li, T, Li, G.Y, Yin, H. | 登録日 | 2021-08-23 | 公開日 | 2022-07-06 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.764 Å) | 主引用文献 | Biocatalytic Baeyer-Villiger Reactions: Uncovering the Source of Regioselectivity at Each Evolutionary Stage of a Mutant with Scrutiny of Fleeting Chiral Intermediates. Acs Catalysis, 12, 2022
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7X3Z
| Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NAD | 分子名称: | (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one, 17-beta-hydroxysteroid dehydrogenase type 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Li, T, Lin, S.X, Yin, H. | 登録日 | 2022-03-01 | 公開日 | 2023-01-25 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | New insights into the substrate inhibition of human 17 beta-hydroxysteroid dehydrogenase type 1. J.Steroid Biochem.Mol.Biol., 228, 2023
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8XKN
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8KGG
| LPS-bound P2Y10 in complex with G13 | 分子名称: | (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | He, Y, Yin, Y. | 登録日 | 2023-08-19 | 公開日 | 2024-07-31 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Insights into lysophosphatidylserine recognition and G alpha 12/13 -coupling specificity of P2Y10. Cell Chem Biol, 2024
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7RJF
| MOPD-1 mutant-L47W | 分子名称: | MALONATE ION, ZINC ION, [L47W]MOPD-1 | 著者 | Huawu, Y, Conan, K.W, Gordon, J.K, Brett, M.C, Yen-Hua, H, David, J.C. | 登録日 | 2021-07-20 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Rational Design of Potent Peptide Inhibitors of the PD-1:PD-L1 Interaction for Cancer Immunotherapy. J.Am.Chem.Soc., 143, 2021
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8W56
| Cryo-EM structure of DSR2-DSAD1 state 1 | 分子名称: | SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI | 著者 | Zhang, H, Li, Z, Li, X.Z. | 登録日 | 2023-08-25 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Insights into the modulation of bacterial NADase activity by phage proteins. Nat Commun, 15, 2024
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8WKN
| Cryo-EM structure of DSR2-DSAD1 | 分子名称: | SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI | 著者 | Zhang, H, Li, Z, Li, X.Z. | 登録日 | 2023-09-28 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Insights into the modulation of bacterial NADase activity by phage proteins. Nat Commun, 15, 2024
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8K98
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8K9A
| Cryo-EM structure of DSR2-DSAD1 state 2 | 分子名称: | SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI | 著者 | Zhang, H, Li, Z, Li, X.Z. | 登録日 | 2023-07-31 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Insights into the modulation of bacterial NADase activity by phage proteins. Nat Commun, 15, 2024
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5WYZ
| Crystal structure of human TLR8 in complex with CU-CPT9b | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(3-methyl-4-oxidanyl-phenyl)quinolin-7-ol, ... | 著者 | Tanji, H, Ohto, U, Shimizu, T. | 登録日 | 2017-01-16 | 公開日 | 2017-12-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Small-molecule inhibition of TLR8 through stabilization of its resting state Nat. Chem. Biol., 14, 2018
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5WYX
| Crystal structure of human TLR8 in complex with CU-CPT8m | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, ... | 著者 | Tanji, H, Ohto, U, Shimizu, T. | 登録日 | 2017-01-16 | 公開日 | 2017-12-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Small-molecule inhibition of TLR8 through stabilization of its resting state Nat. Chem. Biol., 14, 2018
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