4EK7
 
 | | High speed X-ray analysis of plant enzymes at room temperature | | 分子名称: | CHLORIDE ION, Raucaffricine-O-beta-D-glucosidase, beta-D-glucopyranose | | 著者 | Xia, L, Rajendran, C, Ruppert, M, Panjikar, S, Wang, M, Stoeckigt, J. | | 登録日 | 2012-04-09 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | High speed X-ray analysis of plant enzymes at room temperature.
Phytochemistry, 2012
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2V91
 | | STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH STRICTOSIDINE | | 分子名称: | METHYL (2S,3R,4S)-3-ETHYL-2-(BETA-D-GLUCOPYRANOSYLOXY)-4-[(1S)-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLIN-1-YLMETHYL]-3,4-DIHYDRO-2H-PYRAN-5-CARBOXYLATE, STRICTOSIDINE SYNTHASE | | 著者 | Loris, E.A, Panjikar, S, Ruppert, M, Barleben, L, Unger, M, Stoeckigt, J. | | 登録日 | 2007-08-16 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Structure Based Engineering of Strictosidine Synthase: Auxiliary for Alkaloid Libraries
Chem.Biol., 14, 2007
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4ATL
 | | Crystal structure of Raucaffricine glucosidase in complex with Glucose | | 分子名称: | RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, beta-D-glucopyranose | | 著者 | Xia, L, Rajendran, C, Ruppert, M, Panjikar, S, Wang, M, Stoeckigt, J. | | 登録日 | 2012-05-08 | | 公開日 | 2013-01-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | High Speed X-Ray Analysis of Plant Enzymes at Room Temperature
Phytochemistry, 91, 2013
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4ATD
 | | Crystal structure of native Raucaffricine glucosidase | | 分子名称: | RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION | | 著者 | Xia, L, Rajendran, C, Ruppert, M, Panjikar, S, Wang, M, Stoeckigt, J. | | 登録日 | 2012-05-05 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High Speed X-Ray Analysis of Plant Enzymes at Room Temperature
Phytochemistry, 91, 2013
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4IYG
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4IMB
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3ZJ6
 | | Crystal of Raucaffricine Glucosidase in complex with inhibitor | | 分子名称: | (1R,2S,3S,4R,5R)-4-(cyclohexylmethylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triol, RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION | | 著者 | Xia, L, Lin, H, Panjikar, S, Ruppert, M, Castiglia, A, Rajendran, C, Wang, M, Schuebel, H, Warzecha, H, Jaeger, V, Stoeckigt, J. | | 登録日 | 2013-01-17 | | 公開日 | 2014-01-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
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3ZJ7
 | | Crystal structure of strictosidine glucosidase in complex with inhibitor-1 | | 分子名称: | (1R,2S,3S,4R,5R)-4-(cyclohexylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triol, STRICTOSIDINE-O-BETA-D-GLUCOSIDASE | | 著者 | Xia, L, Lin, H, Panjikar, S, Ruppert, M, Castiglia, A, Rajendran, C, Wang, M, Schuebel, H, Warzecha, H, Jaeger, V, Stoeckigt, J. | | 登録日 | 2013-01-17 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
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2BGH
 | | Crystal structure of Vinorine Synthase | | 分子名称: | VINORINE SYNTHASE | | 著者 | Ma, X, Koepke, J, Panjikar, S, Fritzsch, G, Stoeckigt, J. | | 登録日 | 2004-12-22 | | 公開日 | 2005-01-24 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of Vinorine Synthase, the First Representative of the Bahd Superfamily.
J.Biol.Chem., 280, 2005
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6N5V
 | | Crystal Structure of Strictosidine in complex with 1H-indole-4-ethanamine | | 分子名称: | 2-(1H-indol-4-yl)ethan-1-amine, Strictosidine synthase | | 著者 | Cai, Y, Shao, N, Xie, H, Futamura, Y, Panjikar, S, Liu, H, Zhu, H, Osada, H, Zou, H. | | 登録日 | 2018-11-22 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.549 Å) | | 主引用文献 | Crystal Structure of Strictosidine in complex with 1H-indole-4-ethanamine
to be published
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3GZJ
 | | Crystal Structure of Polyneuridine Aldehyde Esterase Complexed with 16-epi-Vellosimine | | 分子名称: | 16-epi-Vellosimine, Polyneuridine-aldehyde esterase | | 著者 | Yang, L, Hill, M, Wang, M, Panjikar, S, Stoeckigt, J. | | 登録日 | 2009-04-07 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structural basis and enzymatic mechanism of the biosynthesis of C9- from C10-monoterpenoid indole alkaloids
Angew.Chem.Int.Ed.Engl., 48, 2009
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2VAQ
 | | STRUCTURE OF STRICTOSIDINE SYNTHASE IN COMPLEX WITH INHIBITOR | | 分子名称: | (2S,3R,4S)-methyl 4-(2-(2-(1H-indol-3-yl)ethylamino)ethyl)-2-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-vinyl-3,4-dihydro-2H-pyran-5-carboxylate, STRICTOSIDINE SYNTHASE | | 著者 | Maresh, J, Giddings, L.A, Friedrich, A, Loris, E.A, Panjikar, S, Trout, B.L, Stoeckigt, J, Peters, B, O'Connor, S.E. | | 登録日 | 2007-09-04 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme.
J. Am. Chem. Soc., 130, 2008
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2WFL
 | | Crystal structure of polyneuridine aldehyde esterase | | 分子名称: | POLYNEURIDINE-ALDEHYDE ESTERASE, SULFATE ION | | 著者 | Yang, L, Hill, M, Panjikar, S, Wang, M, Stoeckigt, J. | | 登録日 | 2009-04-08 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
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2WFM
 | | Crystal structure of polyneuridine aldehyde esterase mutant (H244A) | | 分子名称: | POLYNEURIDINE ALDEHYDE ESTERASE | | 著者 | Yang, L, Hill, M, Panjikar, S, Wang, M, Stoeckigt, J. | | 登録日 | 2009-04-08 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis and Enzymatic Mechanism of the Biosynthesis of C9- from C10-Monoterpenoid Indole Alkaloids.
Angew.Chem.Int.Ed.Engl., 48, 2009
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7T5J
 | | Crystal Structure of Strictosidine Synthase in complex with S-IPA (2-(1H-indol-3-yl) propan-1-amine) | | 分子名称: | (2S)-2-(1H-indol-3-yl)propan-1-amine, Strictosidine synthase | | 著者 | Liu, H, Panjikar, S, Futamura, Y, Shao, N, Osada, H, Zou, H. | | 登録日 | 2021-12-12 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | beta-Branched Tryptamine Provoked Non Sandwich-Like-Mode Catalysis of Strictosidine Synthase to Antimalarial Indole Alkaloids
to be published
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7T5I
 | | Crystal Structure of Strictosidine Synthase in complex with R-IPA(2-(1H-indol-3-yl) propan-1-amine) | | 分子名称: | (2R)-2-(1H-indol-3-yl)propan-1-amine, Strictosidine synthase | | 著者 | Liu, H, Panjikar, S, Futamura, Y, Shao, N, Osada, H, Zou, H. | | 登録日 | 2021-12-12 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Beta-Branched Tryptamine Provoked Non Sandwich-Like-Mode Catalysis of Strictosidine Synthase to Antimalarial Indole Alkaloids
to be published
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3ZJ8
 | | Crystal structure of strictosidine glucosidase in complex with inhibitor-2 | | 分子名称: | (1R,2S,3S,4R,5R)-4-[(4-bromophenyl)methylamino]-5-(hydroxymethyl)cyclopentane-1,2,3-triol, STRICTOSIDINE-O-BETA-D-GLUCOSIDASE | | 著者 | Xia, L, Lin, H, Panjikar, S, Ruppert, M, Castiglia, A, Rajendran, C, Wang, M, Schuebel, H, Warzecha, H, Jaeger, V, Stoeckigt, J. | | 登録日 | 2013-01-17 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
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4A3Y
 | | Crystal structure of Raucaffricine glucosidase from ajmaline biosynthesis pathway | | 分子名称: | GLYCEROL, RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION | | 著者 | Xia, L, Ruppert, M, Wang, M, Panjikar, S, Barleben, L, Rajendran, C, Lin, H, Stoeckigt, J. | | 登録日 | 2011-10-06 | | 公開日 | 2012-08-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity.
Acs Chem.Biol., 7, 2012
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3U57
 | | Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity | | 分子名称: | (2beta,7beta,16S,17R,19E,21beta)-21-(beta-D-glucopyranosyloxy)-2,7-dihydro-7,17-cyclosarpagan-17-yl acetate, CHLORIDE ION, Raucaffricine-O-beta-D-glucosidase | | 著者 | Xia, L, Ruppert, M, Wang, M, Panjikar, S, Lin, H, Rajendran, C, Barleben, L, Stoeckigt, J. | | 登録日 | 2011-10-11 | | 公開日 | 2011-11-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Structures of alkaloid biosynthetic glucosidases decode substrate specificity.
Acs Chem.Biol., 7, 2012
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3U5Y
 | | Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity | | 分子名称: | CHLORIDE ION, Raucaffricine-O-beta-D-glucosidase, Secologanin | | 著者 | Xia, L, Ruppert, M, Wang, M, Panjikar, S, Lin, H, Rajendran, C, Barleben, L, Stoeckigt, J. | | 登録日 | 2011-10-11 | | 公開日 | 2011-11-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of alkaloid biosynthetic glucosidases decode substrate specificity.
Acs Chem.Biol., 7, 2012
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3UYI
 | | Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding | | 分子名称: | Perakine reductase | | 著者 | Sun, L, Chen, Y, Rajendran, C, Panjikar, S, Mueller, U, Wang, M, Rosenthal, C, Mindnich, R, Penning, T.M, Stoeckigt, J. | | 登録日 | 2011-12-06 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.313 Å) | | 主引用文献 | Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
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3V0T
 | | Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding | | 分子名称: | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, Perakine Reductase | | 著者 | Sun, L, Chen, Y, Rajendran, C, Panjikar, S, Mueller, U, Wang, M, Rosenthal, C, Mindnich, R, Penning, T.M, Stoeckigt, J. | | 登録日 | 2011-12-08 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.333 Å) | | 主引用文献 | Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
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3V0U
 | | Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding | | 分子名称: | Perakine reductase | | 著者 | Sun, L, Chen, Y, Rajendran, C, Panjikar, S, Mueller, U, Wang, M, Rosenthal, C, Mindnich, R, Penning, T.M, Stoeckigt, J. | | 登録日 | 2011-12-08 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | | 主引用文献 | Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
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3V0S
 | | Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding | | 分子名称: | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, Perakine reductase | | 著者 | Sun, L, Chen, Y, Rajendran, C, Panjikar, S, Mueller, U, Wang, M, Rosenthal, C, Mindnich, R, Penning, T.M, Stoeckigt, J. | | 登録日 | 2011-12-08 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.773 Å) | | 主引用文献 | Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
J.Biol.Chem., 287, 2012
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3V1S
 | | Scaffold tailoring by a newly detected Pictet-Spenglerase ac-tivity of strictosidine synthase (STR1): from the common tryp-toline skeleton to the rare piperazino-indole framework | | 分子名称: | 2-(1H-indol-1-yl)ethanamine, Strictosidine synthase | | 著者 | Wu, F, Zhu, H, Sun, L, Rajendran, C, Wang, M, Ren, X, Panjikar, S, Cherkasov, A, Zou, H, Stoeckigt, J. | | 登録日 | 2011-12-10 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.328 Å) | | 主引用文献 | Scaffold Tailoring by a Newly Detected Pictet-Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework
J.Am.Chem.Soc., 134, 2012
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