2VQZ
 
 | | Structure of the cap-binding domain of influenza virus polymerase subunit PB2 with bound m7GTP | | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, POLYMERASE BASIC PROTEIN 2 | | 著者 | Guilligay, D, Tarendeau, F, Resa-Infante, P, Coloma, R, Crepin, T, Sehr, P, Lewis, J, Ruigrok, R.W.H, Ortin, J, Hart, D.J, Cusack, S. | | 登録日 | 2008-03-21 | | 公開日 | 2008-05-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Structural Basis for CAP Binding by Influenza Virus Polymerase Subunit Pb2.
Nat.Struct.Mol.Biol., 15, 2008
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2XFM
 | | Complex structure of the MIWI Paz domain bound to methylated single stranded RNA | | 分子名称: | 5'-R(*AP*CP*CP*GP*AP*CP*UP*(OMU)P)-3', PIWI-LIKE PROTEIN 1 | | 著者 | Simon, B, Kirkpatrick, J.P, Eckhardt, S, Sehr, P, Andrade-Navarro, M.A, Pillai, R.S, Carlomagno, T. | | 登録日 | 2010-05-27 | | 公開日 | 2011-01-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Recognition of 2'-O-Methylated 3'-End of Pirna by the Paz Domain of a Piwi Protein.
Structure, 19, 2011
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4CB7
 | | Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 8e) | | 分子名称: | 5-[2-(2-azanyl-7-methyl-6-oxidanylidene-1H-purin-9-ium-9-yl)ethanoyl]-2-oxidanyl-benzoic acid, GLYCEROL, POLYMERASE BASIC SUBUNIT 2 | | 著者 | Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S. | | 登録日 | 2013-10-10 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain
J.Med.Chem., 56, 2013
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4CB5
 | | Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 8f) | | 分子名称: | 9-N-(3-CARBOXY-4-HYDROXYPHENYL)KETOMETHYL-7-N-METHYLGUANINE, CHLORIDE ION, POLYMERASE BASIC SUBUNIT 2 | | 著者 | Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S. | | 登録日 | 2013-10-10 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain
J.Med.Chem., 56, 2013
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4CB6
 | | Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 11) | | 分子名称: | 2,9-N,N-DI(4-CARBOXYBUTYL)-7-N-METHYLGUANINE, IODIDE ION, POLYMERASE BASIC SUBUNIT 2 | | 著者 | Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S. | | 登録日 | 2013-10-10 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain
J.Med.Chem., 56, 2013
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4CB4
 | | Structure of Influenza A H5N1 PB2 cap-binding domain with bound m7GTP | | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, POLYMERASE BASIC SUBUNIT 2 | | 著者 | Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S. | | 登録日 | 2013-10-10 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain
J.Med.Chem., 56, 2013
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6VNR
 | | Crystal Structure of Danio rerio Histone Deacetylase 6 Catalytic Domain 2 (CD2) Complexed with Bishydroxamic Acid Inhibitor | | 分子名称: | 1,2-ETHANEDIOL, Hdac6 protein, N-hydroxy-1-{[4-(hydroxycarbamoyl)phenyl]methyl}-1H-indole-6-carboxamide, ... | | 著者 | Osko, J.D, Porter, N.J, Christianson, D.W. | | 登録日 | 2020-01-29 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.94301319 Å) | | 主引用文献 | Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors.
Chemmedchem, 15, 2020
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6VNQ
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7U59
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6FHH
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6FHI
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7SMD
 | | p107 pocket domain complexed with EID1 peptide | | 分子名称: | EP300-interacting inhibitor of differentiation 1, Retinoblastoma-like protein 1, SULFATE ION | | 著者 | Putta, S, Fernandez, S.M, Tripathi, S.M, Muller, G.A, Rubin, S.M. | | 登録日 | 2021-10-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family.
Structure, 30, 2022
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7SME
 | | p107 pocket domain complexed with HDAC1 peptide | | 分子名称: | Histone deacetylase 1, Retinoblastoma-like protein 1, SULFATE ION | | 著者 | Putta, S, Fernandez, S.M, Tripathi, S.M, Muller, G.A, Rubin, S.M. | | 登録日 | 2021-10-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family.
Structure, 30, 2022
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7SMF
 | | p107 pocket domain complexed with mutated HDAC1-3X peptide | | 分子名称: | Histone deacetylase 1, Retinoblastoma-like protein 1, SULFATE ION | | 著者 | Putta, S, Fernandez, S.M, Tripathi, S.M, Muller, G.A, Rubin, S.M. | | 登録日 | 2021-10-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family.
Structure, 30, 2022
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7SMC
 | | p107 pocket domain complexed with ARID4A peptide | | 分子名称: | AT-rich interactive domain-containing protein 4A, Retinoblastoma-like protein 1, SULFATE ION | | 著者 | Putta, S, Fernandez, S.M, Tripathi, S.M, Muller, G.A, Rubin, S.M. | | 登録日 | 2021-10-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family.
Structure, 30, 2022
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7BJS
 | | Crystal structure of Khc/atypical Tm1 complex | | 分子名称: | Kinesin heavy chain, SD21996p | | 著者 | Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J. | | 登録日 | 2021-01-14 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex.
Genes Dev., 35, 2021
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7BJN
 | | Crystal structure of atypical Tm1 (Tm1-I/C), residues 270-334 | | 分子名称: | SD21996p | | 著者 | Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J. | | 登録日 | 2021-01-14 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex.
Genes Dev., 35, 2021
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7BJG
 | | Crystal structure of atypical Tm1 (Tm1-I/C), residues 262-363 | | 分子名称: | SD21996p | | 著者 | Dimitrova-Paternoga, L, Jagtap, P.K.A, Ephrussi, A, Hennig, J. | | 登録日 | 2021-01-14 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex.
Genes Dev., 35, 2021
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3DS0
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3DS2
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3DS5
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3DTJ
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3DS1
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3DPH
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3DS3
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