8U27
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![BU of 8u27 by Molmil](/molmil-images/mine/8u27) | Bcl-2-xL complexed with compound 35 | 分子名称: | Apoptosis regulator Bcl-2, Bcl-2-like protein 1 chimera, propan-2-yl {4-[(5S)-1-(4-bromobenzoyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl]phenyl}carbamate | 著者 | Rizo, J, Pan, Y.-Z. | 登録日 | 2023-09-05 | 公開日 | 2023-09-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural insights for selective disruption of Beclin 1 binding to Bcl-2. Commun Biol, 6, 2023
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7UDB
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![BU of 7udb by Molmil](/molmil-images/mine/7udb) | Cryo-EM structure of a synaptobrevin-Munc18-1-syntaxin-1 complex class 2 | 分子名称: | Synaptobrevin-2, Syntaxin-1A, Syntaxin-binding protein 1 | 著者 | Rizo, J, Bai, X, Stepien, K.P, Xu, J, Zhang, X. | 登録日 | 2022-03-18 | 公開日 | 2022-04-06 | 最終更新日 | 2022-07-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex. Sci Adv, 8, 2022
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7UDC
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![BU of 7udc by Molmil](/molmil-images/mine/7udc) | cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex class1 | 分子名称: | Synaptobrevin-2, Syntaxin-1A, Syntaxin-binding protein 1 | 著者 | Rizo, J, Bai, X, Stepien, K.P, Xu, J, Zhang, X. | 登録日 | 2022-03-18 | 公開日 | 2022-04-06 | 最終更新日 | 2022-07-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex. Sci Adv, 8, 2022
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4OMO
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4OMN
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4OMP
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![BU of 4omp by Molmil](/molmil-images/mine/4omp) | |
4OML
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4QT7
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1KMD
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![BU of 1kmd by Molmil](/molmil-images/mine/1kmd) | SOLUTION STRUCTURE OF THE VAM7P PX DOMAIN | 分子名称: | Vacuolar morphogenesis protein VAM7 | 著者 | Lu, J, Garcia, J, Dulubova, I, Sudhof, T.C, Rizo, J. | 登録日 | 2001-12-14 | 公開日 | 2002-06-12 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Vam7p PX domain. Biochemistry, 41, 2002
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6ANJ
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![BU of 6anj by Molmil](/molmil-images/mine/6anj) | Synaptotagmin-7, C2A domain | 分子名称: | ACETATE ION, CALCIUM ION, Synaptotagmin-7, ... | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | 登録日 | 2017-08-13 | 公開日 | 2017-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1KIL
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![BU of 1kil by Molmil](/molmil-images/mine/1kil) | Three-dimensional structure of the complexin/SNARE complex | 分子名称: | Complexin I SNARE-complex binding region, MAGNESIUM ION, SNAP-25 C-terminal SNARE motif, ... | 著者 | Chen, X, Tomchick, D, Kovrigin, E, Arac, D, Machius, M, Sudhof, T.C, Rizo, J. | 登録日 | 2001-12-03 | 公開日 | 2002-03-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Three-dimensional structure of the complexin/SNARE complex. Neuron, 33, 2002
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5UF7
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6ANK
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![BU of 6ank by Molmil](/molmil-images/mine/6ank) | Synaptotagmin-7, C2A- and C2B-domains | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7 | 著者 | Tomchick, D.R, Rizo, J, Voleti, R. | 登録日 | 2017-08-13 | 公開日 | 2017-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.254 Å) | 主引用文献 | Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UE8
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3SWH
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4Y21
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![BU of 4y21 by Molmil](/molmil-images/mine/4y21) | Crystal Structure of Munc13-1 MUN domain | 分子名称: | Protein unc-13 homolog A | 著者 | Yang, X.Y, Wang, S, Sheng, Y, Zhang, M, Zou, W.J, Wu, L.J, Kang, L.J, Rizo, J, Zhang, R.G, Xu, T, Ma, C. | 登録日 | 2015-02-09 | 公開日 | 2015-06-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming. Nat.Struct.Mol.Biol., 22, 2015
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2Q3X
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![BU of 2q3x by Molmil](/molmil-images/mine/2q3x) | The RIM1alpha C2B domain | 分子名称: | CHLORIDE ION, Regulating synaptic membrane exocytosis protein 1, SODIUM ION, ... | 著者 | Guan, R, Dai, H, Tomchick, D.R, Machius, M, Sudhof, T.C, Rizo, J. | 登録日 | 2007-05-30 | 公開日 | 2007-08-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution. Biochemistry, 46, 2007
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2CJS
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![BU of 2cjs by Molmil](/molmil-images/mine/2cjs) | Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, ... | 著者 | Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J. | 登録日 | 2006-04-06 | 公開日 | 2006-06-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural Basis for a Munc13-1 Homodimer to Munc13-1/Rim Heterodimer Switch. Plos Biol., 4, 2006
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2CJT
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![BU of 2cjt by Molmil](/molmil-images/mine/2cjt) | Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, UNC-13 HOMOLOG A | 著者 | Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J. | 登録日 | 2006-04-06 | 公開日 | 2006-06-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Structural Basis for a Munc13-1 Dimeric to Munc13-1/Rim Heterodimer Switch Plos Biol., 4, 2006
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1S2H
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![BU of 1s2h by Molmil](/molmil-images/mine/1s2h) | The Mad2 spindle checkpoint protein possesses two distinct natively folded states | 分子名称: | Mitotic spindle assembly checkpoint protein MAD2A | 著者 | Luo, X, Tang, Z, Xia, G, Wassmann, K, Matsumoto, T, Rizo, J, Yu, H. | 登録日 | 2004-01-08 | 公開日 | 2004-03-30 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat.Struct.Mol.Biol., 11, 2004
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3N5A
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![BU of 3n5a by Molmil](/molmil-images/mine/3n5a) | Synaptotagmin-7, C2B-domain, calcium bound | 分子名称: | CALCIUM ION, Synaptotagmin-7 | 著者 | Tomchick, D.R, Rizo, J, Craig, T.K. | 登録日 | 2010-05-24 | 公開日 | 2010-09-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.441 Å) | 主引用文献 | Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. Plos One, 5, 2010
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6NYT
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![BU of 6nyt by Molmil](/molmil-images/mine/6nyt) | Munc13-1 C2B-domain, calcium bound | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | 登録日 | 2019-02-12 | 公開日 | 2019-02-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.369 Å) | 主引用文献 | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat. Struct. Mol. Biol., 17, 2010
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6NYC
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![BU of 6nyc by Molmil](/molmil-images/mine/6nyc) | Munc13-1 C2B-domain, calcium free | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Munc13-1 | 著者 | Tomchick, D.R, Rizo, J, Machius, M, Lu, J. | 登録日 | 2019-02-11 | 公開日 | 2019-02-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | 主引用文献 | Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat. Struct. Mol. Biol., 17, 2010
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1Y9J
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![BU of 1y9j by Molmil](/molmil-images/mine/1y9j) | Solution structure of the rat Sly1 N-terminal domain | 分子名称: | Sec1 family domain containing protein 1 | 著者 | Arac, D, Dulubova, I, Pei, J, Huryeva, I, Grishin, N.V, Rizo, J. | 登録日 | 2004-12-15 | 公開日 | 2005-02-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional Structure of the rSly1 N-terminal Domain Reveals a Conformational Change Induced by Binding to Syntaxin 5. J.Mol.Biol., 346, 2005
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1BR0
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![BU of 1br0 by Molmil](/molmil-images/mine/1br0) | THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A | 分子名称: | PROTEIN (SYNTAXIN 1-A) | 著者 | Fernandez, I, Ubach, J, Dubulova, I, Zhang, X, Sudhof, T.C, Rizo, J. | 登録日 | 1998-08-25 | 公開日 | 1998-09-02 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A. Cell(Cambridge,Mass.), 94, 1998
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