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The crystal structure of Corynebacterium glutamicum dihydrodipicolinate synthase to 2.2 A resolution
分子名称:	Dihydrodipicolinate synthetase
著者	Rydel, T.J, Sturman, E.J, Rice, E.A.
登録日	2008-04-01
公開日	2008-11-18
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Characterization and crystal structure of lysine insensitive Corynebacterium glutamicum dihydrodipicolinate synthase (cDHDPS) protein. Arch.Biochem.Biophys., 480, 2008

Crystal Structure of Human Beta Secretase Complexed with inhibitor
分子名称:	Beta-secretase 1, N-[(5R,14R)-5-AMINO-5,14-DIMETHYL-4-OXO-3-OXA-18-AZATRICYCLO[15.3.1.1~7,11~]DOCOSA-1(21),7(22),8,10,17,19-HEXAEN-19-YL]-N-METHYLMETHANESULFONAMIDE, SULFATE ION
著者	Munshi, S.
登録日	2007-04-10
公開日	2008-04-22
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007

Crystal Structure of Human Beta Secretase Complexed with inhibitor
分子名称:	3-({[(1R)-1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)-5-[METHYL(METHYLSULFONYL)AMINO]BENZYL ALPHA-METHYL-D-PHENYLALANINATE, Beta-secretase 1, SULFATE ION
著者	Munshi, S.
登録日	2007-04-10
公開日	2007-06-05
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007

Crystal structure of human Beta Secretase complexed with I21
分子名称:	2-[(5R)-5-amino-5-methyl-4,16-dioxo-14-phenyl-3-oxa-15-azatricyclo[15.3.1.1~7,11~]docosa-1(21),7(22),8,10,12,14,17,19-octaen-19-yl]benzonitrile, Beta-secretase 1
著者	Munshi, S.
登録日	2007-08-16
公開日	2008-04-29
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007