6XZ2
| |
7OOZ
| Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzyloxo-2-chloropurine | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-benzyloxo-2-chloropurine, GLYCEROL, ... | 著者 | Narczyk, M, Stefanic, Z. | 登録日 | 2021-05-28 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
|
|
7OP9
| Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 2,6-dichloropurine | 分子名称: | 2,6-bis(chloranyl)-7H-purine, IMIDAZOLE, MAGNESIUM ION, ... | 著者 | Narczyk, M, Stefanic, Z. | 登録日 | 2021-05-31 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
|
|
7OPA
| Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzylthiopurine | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-benzylthio-2-chloropurine, GLYCEROL, ... | 著者 | Narczyk, M, Stefanic, Z. | 登録日 | 2021-05-31 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
|
|
7OOY
| Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzylthio-2-chloropurine | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-benzylthio-2-chloropurine, GLYCEROL, ... | 著者 | Narczyk, M, Stefanic, Z. | 登録日 | 2021-05-28 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
|
|
7PVO
| |
3FUC
| Recombinant calf purine nucleoside phosphorylase in a binary complex with multisubstrate analogue inhibitor 9-(5',5'-difluoro-5'-phosphonopentyl)-9-deazaguanine structure in a new space group with one full trimer in the asymmetric unit | 分子名称: | AZIDE ION, MAGNESIUM ION, Purine nucleoside phosphorylase, ... | 著者 | Bochtler, M, Breer, K, Bzowska, A, Chojnowski, G, Hashimoto, M, Hikishima, S, Narczyk, M, Wielgus-Kutrowska, B, Yokomatsu, T. | 登録日 | 2009-01-14 | 公開日 | 2009-12-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | 1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state. Biochem.Biophys.Res.Commun., 391, 2010
|
|
5LU0
| Crystal structure of H. pylori referent strain in complex with PO4 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, ... | 著者 | Stefanic, Z. | 登録日 | 2016-09-07 | 公開日 | 2017-09-20 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
|
|
6F52
| |
6F4W
| |
6F5I
| Crystal structure of H. pylori purine nucleoside phosphorylase | 分子名称: | METHANOL, Purine nucleoside phosphorylase DeoD-type | 著者 | Stefanic, Z. | 登録日 | 2017-12-01 | 公開日 | 2018-02-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | 主引用文献 | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
|
|
6F5A
| Crystal structure of H. pylori purine nucleoside phosphorylase | 分子名称: | Purine nucleoside phosphorylase DeoD-type | 著者 | Stefanic, Z. | 登録日 | 2017-12-01 | 公開日 | 2018-02-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
|
|
6F4X
| |
7T7H
| Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with inhibitor CP100356 | 分子名称: | 4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxyquinazolin-2-amine, DNA repair NTP-phosphohydrolase, SODIUM ION | 著者 | Peters, J.K, Gross, J.D. | 登録日 | 2021-12-15 | 公開日 | 2022-06-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.78000259 Å) | 主引用文献 | Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9. Acs Chem.Biol., 17, 2022
|
|
6ZXQ
| Adenylosuccinate Synthetase from H. pylori in complex with HDA, GDP, IMO, Mg | 分子名称: | 6-O-PHOSPHORYL INOSINE MONOPHOSPHATE, Adenylosuccinate synthetase, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Bubic, A, Stefanic, Z. | 登録日 | 2020-07-30 | 公開日 | 2021-08-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The pursuit of new alternative ways to eradicate Helicobacter pylori continues: Detailed characterization of interactions in the adenylosuccinate synthetase active site Int.J.Biol.Macromol., 2023
|
|
3UT6
| Crystal structure of E. Coli PNP complexed with PO4 and formycin A | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type | 著者 | Stefanic, Z. | 登録日 | 2011-11-25 | 公開日 | 2012-05-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A. Febs Lett., 586, 2012
|
|
3OOH
| Crystal structure of E. Coli purine nucleoside phosphorylase with PO4 | 分子名称: | PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type | 著者 | Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M. | 登録日 | 2010-08-31 | 公開日 | 2011-07-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies. Biochimie, 93, 2011
|
|
3OPV
| Crystal structure of E. Coli purine nucleoside phosphorylase Arg24Ala mutant | 分子名称: | PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type | 著者 | Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M. | 登録日 | 2010-09-02 | 公開日 | 2011-07-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies. Biochimie, 93, 2011
|
|
4TS9
| |
4TTJ
| Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 6 FMC molecules | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type, ... | 著者 | Stefanic, Z, Bzowska, A. | 登録日 | 2014-06-21 | 公開日 | 2015-07-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.874 Å) | 主引用文献 | Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis. Sci Rep, 8, 2018
|
|
4TTA
| Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 2 FMC molecules | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type, ... | 著者 | Stefanic, Z, Bzowska, A. | 登録日 | 2014-06-20 | 公開日 | 2015-07-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis. Sci Rep, 8, 2018
|
|
3OOE
| Crystal structure of E. Coli purine nucleoside phosphorylase with PO4 | 分子名称: | PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type | 著者 | Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M. | 登録日 | 2010-08-31 | 公開日 | 2011-07-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies. Biochimie, 93, 2011
|
|
4TTI
| Crystal structure of double mutant E. Coli purine nucleoside phosphorylase with 4 FMC molecules | 分子名称: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type, ... | 著者 | Stefanic, Z, Bzowska, A. | 登録日 | 2014-06-21 | 公開日 | 2015-07-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis. Sci Rep, 8, 2018
|
|
4TS3
| |
3ONV
| Crystal structure of E. Coli purine nucleoside phosphorylase with SO4 | 分子名称: | Purine nucleoside phosphorylase deoD-type, SULFATE ION | 著者 | Mikleusevic, G, Stefanic, Z, Narzyk, M, Wielgus-Kutrowska, B, Bzowska, A, Luic, M. | 登録日 | 2010-08-30 | 公開日 | 2011-07-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | 主引用文献 | Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies. Biochimie, 93, 2011
|
|