8SQH
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![BU of 8sqh by Molmil](/molmil-images/mine/8sqh) | SpRY-Cas9:gRNA complex targeting TTC PAM DNA | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-05-04 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8SRS
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![BU of 8srs by Molmil](/molmil-images/mine/8srs) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-05-06 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8SPQ
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![BU of 8spq by Molmil](/molmil-images/mine/8spq) | SpRY-Cas9:gRNA complex targeting TGG PAM DNA | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-05-03 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T6S
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![BU of 8t6s by Molmil](/molmil-images/mine/8t6s) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 10 bp R-loop | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T6T
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![BU of 8t6t by Molmil](/molmil-images/mine/8t6t) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 13 bp R-loop | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T6O
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![BU of 8t6o by Molmil](/molmil-images/mine/8t6o) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 0 bp R-loop | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-16 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T6Y
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![BU of 8t6y by Molmil](/molmil-images/mine/8t6y) | SpRY-Cas9:gRNA complex bound to non-target DNA with 1 bp R-loop | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-19 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T78
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![BU of 8t78 by Molmil](/molmil-images/mine/8t78) | SpRY-Cas9:gRNA complex bound to non-target DNA with 8 bp R-loop | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-19 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T76
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![BU of 8t76 by Molmil](/molmil-images/mine/8t76) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 3 bp R-loop | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-19 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T77
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![BU of 8t77 by Molmil](/molmil-images/mine/8t77) | SpRY-Cas9:gRNA complex bound to non-target DNA with 6 bp R-loop | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-19 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T6P
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![BU of 8t6p by Molmil](/molmil-images/mine/8t6p) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 2 bp R-loop | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-16 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T7S
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![BU of 8t7s by Molmil](/molmil-images/mine/8t7s) | SpRYmer bound to NAC PAM DNA | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-21 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T6X
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![BU of 8t6x by Molmil](/molmil-images/mine/8t6x) | SpRY-Cas9:gRNA complex targeting TAC PAM DNA with 18 bp R-loop | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-19 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8T79
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![BU of 8t79 by Molmil](/molmil-images/mine/8t79) | SpRY-Cas9:gRNA complex bound to non-target DNA with 10 bp R-loop | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | 著者 | Hibshman, G.N, Bravo, J.P.K, Taylor, D.W. | 登録日 | 2023-06-20 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8U3Y
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![BU of 8u3y by Molmil](/molmil-images/mine/8u3y) | SpG Cas9 with NGG PAM DNA target | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*CP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ... | 著者 | Bravo, J.P.K, Hibshman, G.N, Taylor, D.W. | 登録日 | 2023-09-08 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8TZZ
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![BU of 8tzz by Molmil](/molmil-images/mine/8tzz) | SpG Cas9 with NGC PAM DNA target | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*GP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ... | 著者 | Bravo, J.P.K, Hibshman, G.N, Taylor, D.W. | 登録日 | 2023-08-28 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9. Nat Commun, 15, 2024
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8DFS
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![BU of 8dfs by Molmil](/molmil-images/mine/8dfs) | type I-C Cascade bound to AcrIF2 | 分子名称: | Anti-CRISPR protein 30, CRISPR-associated protein, CT1133 family, ... | 著者 | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | 登録日 | 2022-06-22 | 公開日 | 2023-02-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Mol.Cell, 83, 2023
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8DFO
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![BU of 8dfo by Molmil](/molmil-images/mine/8dfo) | type I-C Cascade bound to AcrIC4 | 分子名称: | AcrIC4, CRISPR-associated protein, CT1133 family, ... | 著者 | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | 登録日 | 2022-06-22 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Mol.Cell, 83, 2023
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8DEJ
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![BU of 8dej by Molmil](/molmil-images/mine/8dej) | D. vulgaris type I-C Cascade bound to dsDNA target | 分子名称: | CRISPR-associated protein, CT1133 family, TM1801 family, ... | 著者 | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | 登録日 | 2022-06-20 | 公開日 | 2023-02-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Mol.Cell, 83, 2023
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8DFA
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![BU of 8dfa by Molmil](/molmil-images/mine/8dfa) | type I-C Cascade bound to ssDNA target | 分子名称: | CRISPR-associated protein, CT1133 family, TM1801 family, ... | 著者 | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | 登録日 | 2022-06-21 | 公開日 | 2023-02-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Mol.Cell, 83, 2023
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8DEX
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![BU of 8dex by Molmil](/molmil-images/mine/8dex) | type I-C Cascade | 分子名称: | CRISPR-associated protein, CT1133 family, TM1801 family, ... | 著者 | O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. | 登録日 | 2022-06-21 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Mol.Cell, 83, 2023
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7S4U
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![BU of 7s4u by Molmil](/molmil-images/mine/7s4u) | Cryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-point | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand, Target strand, ... | 著者 | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | 登録日 | 2021-09-09 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | 主引用文献 | Structural basis for mismatch surveillance by CRISPR-Cas9. Nature, 603, 2022
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7S4V
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![BU of 7s4v by Molmil](/molmil-images/mine/7s4v) | Cas9 bound to 12-14MM DNA, 60 min time-point, kinked conformation | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | 著者 | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | 登録日 | 2021-09-09 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Structural basis for mismatch surveillance by CRISPR-Cas9. Nature, 603, 2022
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7S4X
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![BU of 7s4x by Molmil](/molmil-images/mine/7s4x) | Cas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformation | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | 著者 | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | 登録日 | 2021-09-09 | 公開日 | 2022-03-02 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Structural basis for mismatch surveillance by CRISPR-Cas9. Nature, 603, 2022
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