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2VB5
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Solution structure of W60G mutant of human beta2-microglobulin
分子名称: BETA-2-MICROGLOBULIN
著者Esposito, G, Corazza, A, Rennella, E, Gumral, D, Mimmi, M.C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M, Bellotti, V.
登録日2007-09-06
公開日2007-09-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Controlling Roles of Trp60 and Trp95 in Beta2-Microglobulin Function, Folding and Amyloid Aggregation Properties.
J.Mol.Biol., 378, 2008
1FTT
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BU of 1ftt by Molmil
THYROID TRANSCRIPTION FACTOR 1 HOMEODOMAIN (RATTUS NORVEGICUS)
分子名称: THYROID TRANSCRIPTION FACTOR 1 HOMEODOMAIN
著者Fogolari, F, Esposito, G, Damante, G, Formisano, S, Di Lauro, R, Viglino, P.
登録日1995-10-03
公開日1996-01-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Analysis of the solution structure of the homeodomain of rat thyroid transcription factor 1 by 1H-NMR spectroscopy and restrained molecular mechanics.
Eur.J.Biochem., 241, 1996
1Y9O
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BU of 1y9o by Molmil
1H NMR Structure of Acylphosphatase from the hyperthermophile Sulfolobus Solfataricus
分子名称: Acylphosphatase
著者Corazza, A, Rosano, C, Pagano, K, Alverdi, V, Esposito, G, Capanni, C, Bemporad, F, Plakoutsi, G, Stefani, M, Chiti, F, Zuccotti, S, Bolognesi, M, Viglino, P.
登録日2004-12-16
公開日2005-11-29
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure, conformational stability, and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus
Proteins, 62, 2006
1JNJ
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BU of 1jnj by Molmil
NMR solution structure of the human beta2-microglobulin
分子名称: beta2-microglobulin
著者Verdone, G, Corazza, A, Viglino, P, Pettirossi, F, Giorgetti, S, Mangione, P, Andreola, A, Stoppini, M, Bellotti, V, Esposito, G.
登録日2001-07-24
公開日2002-02-27
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献The solution structure of human beta2-microglobulin reveals the prodromes of its amyloid transition.
Protein Sci., 11, 2002
2OII
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BU of 2oii by Molmil
Structure of EMILIN-1 C1q-like domain
分子名称: EMILIN-1
著者Verdone, G, Colebrooke, S.A, Corazza, A, Cicero, D.O, Eliseo, T, Viglino, P, Campbell, I.D, Colombatti, A, Esposito, G.
登録日2007-01-11
公開日2008-01-22
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The solution structure of the C-terminal domain of EMILIN-1
To be Published
7EH3
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BU of 7eh3 by Molmil
Structure of Nanobody Nb23 in solution using NMR spectroscopy
分子名称: Nb23
著者Percipalle, M, Hunashal, Y, Esposito, G, Fogolari, F.
登録日2021-03-28
公開日2021-07-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of Nanobody Nb23.
Molecules, 26, 2021
2KA3
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BU of 2ka3 by Molmil
Structure of EMILIN-1 C1Q-like domain
分子名称: EMILIN-1
著者Verdone, G, Corazza, A, Colebrooke, S.A, Cicero, D.O, Eliseo, T, Boyd, J, Doliana, R, Fogolari, F, Viglino, P, Colombatti, A, Campbell, I.D, Esposito, G.
登録日2008-10-30
公開日2008-11-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1
J.Biomol.Nmr, 43, 2009
2GV1
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BU of 2gv1 by Molmil
NMR solution structure of the Acylphosphatase from Eschaerichia Coli
分子名称: Probable acylphosphatase
著者Pagano, K, Corazza, A, Viglino, P, Esposito, G.
登録日2006-05-02
公開日2006-10-31
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献NMR solution structure of the acylphosphatase from Escherichia coli.
J.Biomol.Nmr, 36, 2006
1PY4
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Beta2 microglobulin mutant H31Y displays hints for amyloid formations
分子名称: Beta-2-microglobulin precursor
著者Rosano, C, Zuccotti, S, Mangione, P, Giorgetti, S, Bellotti, V, Pettirossi, F, Corazza, A, Viglino, P, Esposito, G, Bolognesi, M.
登録日2003-07-08
公開日2004-05-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation
J.Mol.Biol., 335, 2004
2K27
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BU of 2k27 by Molmil
Solution structure of Human Pax8 Paired Box Domain
分子名称: Paired box protein Pax-8
著者Codutti, L, Esposito, G, Corazza, A, Fogolari, F, Tell, G, Vascotto, C, van Ingen, H, Boelens, R, Viglino, P, Quadrifoglio, F.
登録日2008-03-26
公開日2008-09-30
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献The Solution Structure of DNA-free Pax-8 Paired Box Domain Accounts for Redox Regulation of Transcriptional Activity in the Pax Protein Family.
J.Biol.Chem., 283, 2008
2Z9T
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BU of 2z9t by Molmil
Crystal structure of the human beta-2 microglobulin mutant W60G
分子名称: Beta-2-microglobulin
著者Ricagno, S, Bolognesi, M, Bellotti, V, Corazza, A, Rennella, E, Gural, D, Mimmi, M.C, Betto, E, Pucillo, C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M.
登録日2007-09-26
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties
J.Mol.Biol., 378, 2008
2BJE
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BU of 2bje by Molmil
Acylphosphatase from Sulfolobus solfataricus. Monclinic P21 space group
分子名称: ACYLPHOSPHATASE, CHLORIDE ION, SULFATE ION
著者Rosano, C, Zuccotti, S.
登録日2005-02-02
公開日2005-11-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
2BJD
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BU of 2bjd by Molmil
Sulfolobus Solfataricus Acylphosphatase. Triclinic space group
分子名称: ACYLPHOSPHATASE, CADMIUM ION, CHLORIDE ION, ...
著者Rosano, C, Zuccotti, S, Bolognesi, M.
登録日2005-02-02
公開日2005-11-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
3MKP
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BU of 3mkp by Molmil
Crystal structure of 1K1 mutant of Hepatocyte Growth Factor/Scatter Factor fragment NK1 in complex with heparin
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Gherardi, E, Chirgadze, D.Y, Blundell, T.L.
登録日2010-04-15
公開日2010-08-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Engineering a fragment of Hepatocyte Growth Factor/Scatter Factor for tissue and organ regeneration
To be Published
3QDA
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BU of 3qda by Molmil
Crystal structure of W95L beta-2 microglobulin
分子名称: Beta-2-microglobulin, TRIETHYLENE GLYCOL
著者Ricagno, S, Bellotti, V, Bolognesi, M.
登録日2011-01-18
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献The two tryptophans of beta2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure.
BMC Evol Biol, 11, 2011
5CKA
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BU of 5cka by Molmil
Human beta-2 microglobulin double mutant W60G-N83V
分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
登録日2015-07-15
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CKG
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Human beta-2 microglobulin mutant V85E
分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL
著者Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
登録日2015-07-15
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CFH
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human beta-2 microglobulin double mutant W60G-Y63W
分子名称: Beta-2-microglobulin
著者Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
登録日2015-07-08
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
4M3K
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Structure of a single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase from Bacillus licheniformis
分子名称: Beta-lactamase, CHLORIDE ION, Camelid heavy-chain antibody variable fragment cAb-H7S
著者Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
登録日2013-08-06
公開日2014-08-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
4M3J
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Structure of a single-domain camelid antibody fragment cAb-H7S specific of the BlaP beta-lactamase from Bacillus licheniformis
分子名称: Camelid heavy-chain antibody variable fragment cAb-H7S, SULFATE ION
著者Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
登録日2013-08-06
公開日2014-08-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
4L29
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BU of 4l29 by Molmil
Structure of wtMHC class I with NY-ESO1 double mutant
分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
著者Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
登録日2013-06-04
公開日2013-12-25
最終更新日2014-02-26
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
4L3C
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Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant
分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
著者Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
登録日2013-06-05
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
4N1H
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Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis
分子名称: Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N
著者Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
登録日2013-10-04
公開日2014-10-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
7RKT
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Naegleria fowleri CYP51 (NfCYP51) complex with (S)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl 3-(trifluoromethyl)benzoate
分子名称: (1S)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl 3-(trifluoromethyl)benzoate, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Sharma, V, Podust, L.M.
登録日2021-07-22
公開日2022-07-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri -Specific CYP51 Inhibitors.
J.Med.Chem., 2023
7RKW
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Naegleria fowleri CYP51(NfCYP51) complex with (S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl 3,5-dichlorobenzoate
分子名称: (1S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl 3,5-dichlorobenzoate, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Sharma, V, Podust, L.M.
登録日2021-07-22
公開日2022-07-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri -Specific CYP51 Inhibitors.
J.Med.Chem., 2023

 

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