8XZD
| |
8XYZ
| The structure of fox ACE2 and PT RBD complex | 分子名称: | Angiotensin-converting enzyme, Signal peptide, Spike protein S1, ... | 著者 | sun, J.Q. | 登録日 | 2024-01-20 | 公開日 | 2024-07-03 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | The binding and structural basis of fox ACE2 to RBDs from different sarbecoviruses. Virol Sin, 39, 2024
|
|
8XZB
| The structure of fox ACE2 and SARS-CoV RBD complex | 分子名称: | Angiotensin-converting enzyme, Spike protein S1, ZINC ION | 著者 | sun, J.Q. | 登録日 | 2024-01-21 | 公開日 | 2024-07-03 | 最終更新日 | 2024-09-11 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | The binding and structural basis of fox ACE2 to RBDs from different sarbecoviruses. Virol Sin, 39, 2024
|
|
6CFD
| ADEP4 bound to E. faecium ClpP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit, N-[(6aS,12S,15aS,17R,21R,23aS)-17,21-dimethyl-6,11,15,20,23-pentaoxooctadecahydro-2H,6H,11H,15H-pyrido[2,1-i]dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13]oxatetraazacyclohexadecin-12-yl]-3,5-difluoro-Nalpha-[(2E)-hept-2-enoyl]-L-phenylalaninamide | 著者 | Lee, R.E, Griffith, E.C. | 登録日 | 2018-02-14 | 公開日 | 2018-05-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | In VivoandIn VitroEffects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci. Antimicrob. Agents Chemother., 62, 2018
|
|
5D9Y
| Crystal structure of TET2-5fC complex | 分子名称: | DNA (5'-D(*AP*CP*TP*GP*TP*(5FC)P*GP*AP*AP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*TP*TP*CP*GP*AP*CP*AP*GP*T)-3'), FE (III) ION, ... | 著者 | Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y. | 登録日 | 2015-08-19 | 公開日 | 2015-11-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.971 Å) | 主引用文献 | Structural insight into substrate preference for TET-mediated oxidation. Nature, 527, 2015
|
|
5DEU
| Crystal structure of TET2-5hmC complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, DNA (5'-D(*AP*CP*CP*AP*CP*(5HC)P*GP*GP*TP*GP*GP*T)-3'), ... | 著者 | Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y. | 登録日 | 2015-08-26 | 公開日 | 2015-11-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Structural insight into substrate preference for TET-mediated oxidation. Nature, 527, 2015
|
|
3JVS
| Characterization of the Chk1 allosteric inhibitor binding site | 分子名称: | 2-[(4-tert-butyl-3-nitrophenyl)carbonyl]-N-naphthalen-1-ylhydrazinecarboxamide, Serine/threonine-protein kinase Chk1 | 著者 | Chen, P. | 登録日 | 2009-09-17 | 公開日 | 2009-10-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Characterization of the CHK1 allosteric inhibitor binding site. Biochemistry, 48, 2009
|
|
3JVR
| |
6IRG
| Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class II | 分子名称: | Glutamate receptor ionotropic, NMDA 1, NMDA 2A | 著者 | Zhang, J, Chang, S, Zhang, X, Zhu, S. | 登録日 | 2018-11-12 | 公開日 | 2019-01-16 | 最終更新日 | 2019-06-05 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors Cell Rep, 25, 2018
|
|
6IRA
| Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 7.8 | 分子名称: | Glutamate receptor ionotropic, NMDA 1, NMDA 2A | 著者 | Zhang, J, Chang, S, Zhang, X, Zhu, S. | 登録日 | 2018-11-12 | 公開日 | 2019-01-16 | 最終更新日 | 2019-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors Cell Rep, 25, 2018
|
|
7MON
| Structure of human RIPK3-MLKL complex | 分子名称: | Mixed lineage kinase domain-like protein, N-[4-({2-[(cyclopropanecarbonyl)amino]pyridin-4-yl}oxy)-3-fluorophenyl]-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 3 | 著者 | Meng, Y, Davies, K.A, Czabotar, P.E, Murphy, J.M. | 登録日 | 2021-05-03 | 公開日 | 2021-11-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis. Nat Commun, 12, 2021
|
|
7MX3
| Crystal structure of human RIPK3 complexed with GSK'843 | 分子名称: | 1,2-ETHANEDIOL, 3-(1,3-benzothiazol-5-yl)-7-(1,3-dimethyl-1H-pyrazol-5-yl)thieno[3,2-c]pyridin-4-amine, Receptor-interacting serine/threonine-protein kinase 3 | 著者 | Davies, K.A, Czabotar, P.E. | 登録日 | 2021-05-18 | 公開日 | 2021-11-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | 主引用文献 | Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis. Nat Commun, 12, 2021
|
|
8E86
| |
8E8A
| Human DNA polymerase eta-DNA-dT-ended primer binary complex | 分子名称: | DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta | 著者 | Chang, C, Gao, Y. | 登録日 | 2022-08-25 | 公開日 | 2023-02-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
|
|
8E87
| |
8E8J
| |
8E8B
| |
8E8G
| |
8E8D
| |
8E8C
| |
8E89
| Human DNA polymerase eta-DNA-rU-ended primer-binary complex | 分子名称: | DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, DNA/RNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*U)-3') | 著者 | Chang, C, Gao, Y. | 登録日 | 2022-08-25 | 公開日 | 2023-02-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
|
|
8E8H
| |
8E85
| |
8E88
| |
8E8F
| |