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6VT4
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BU of 6vt4 by Molmil
Naegleria gruberi RNA ligase R149A mutant apo
分子名称: RNA Ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VTE
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BU of 6vte by Molmil
Naegleria gruberi RNA Ligase K170M mutant with AMP and Mn
分子名称: ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, RNA ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
6VT8
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BU of 6vt8 by Molmil
Naegleria gruberi RNA ligase E312A mutant with AMP and Mn
分子名称: ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, RNA Ligase
著者Unciuleac, M.C, Goldgur, Y, Shuman, S.
登録日2020-02-12
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.
Nucleic Acids Res., 48, 2020
4KYY
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BU of 4kyy by Molmil
Crystal Structure of RNA 17-mer UUCGGUUUUGAUCCGGA duplex
分子名称: POTASSIUM ION, RNA 17-mer
著者Smith, P.C, Shuman, S.
登録日2013-05-29
公開日2013-06-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structure of RNA 17-mer UUCGGUUUUGAUCCGGA duplex
To be Published
4O87
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BU of 4o87 by Molmil
Crystal structure of a N-tagged Nuclease
分子名称: CITRIC ACID, N-tagged Nuclease, SULFATE ION
著者Chakravarty, A.K, Smith, P, Shuman, S.
登録日2013-12-26
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination.
Cell Rep, 7, 2014
4O88
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BU of 4o88 by Molmil
Crystal structure of a C-tagged Nuclease
分子名称: CHLORIDE ION, N-tagged Nuclease, SULFATE ION
著者Chakravarty, A.K, Smith, P, Shuman, S.
登録日2013-12-26
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination.
Cell Rep, 7, 2014
4PN0
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BU of 4pn0 by Molmil
Structure of S. pombe Pct1 RNA triphosphatase
分子名称: mRNA-capping enzyme subunit beta
著者Lima, C.D, Doamekpor, S.K.
登録日2014-05-22
公開日2014-11-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Fission yeast RNA triphosphatase reads an Spt5 CTD code.
Rna, 21, 2015
5TT6
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BU of 5tt6 by Molmil
T4 RNA Ligase 1 (K99M)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, T4 RNA ligase 1
著者Goldgur, Y, Unciuleac, M.-C, Shuman, S.H.
登録日2016-11-01
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.187 Å)
主引用文献Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD(+)-dependent polynucleotide ligases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TT5
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BU of 5tt5 by Molmil
Escherichia coli LigA (K115M) in complex with NAD+
分子名称: DNA ligase, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Goldgur, Y, Unciuleac, M.-C, Shuman, S.H.
登録日2016-11-01
公開日2017-03-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.552 Å)
主引用文献Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD(+)-dependent polynucleotide ligases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1CKN
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BU of 1ckn by Molmil
STRUCTURE OF GUANYLYLATED MRNA CAPPING ENZYME COMPLEXED WITH GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, MRNA CAPPING ENZYME, ...
著者Hakansson, K, Doherty, A.J, Wigley, D.B.
登録日1997-04-20
公開日1997-07-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes.
Cell(Cambridge,Mass.), 89, 1997
1CKM
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BU of 1ckm by Molmil
STRUCTURE OF TWO DIFFERENT CONFORMATIONS OF MRNA CAPPING ENZYME IN COMPLEX WITH GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MRNA CAPPING ENZYME
著者Hakansson, K, Doherty, A.J, Wigley, D.B.
登録日1997-04-20
公開日1997-07-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes.
Cell(Cambridge,Mass.), 89, 1997
3EF1
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BU of 3ef1 by Molmil
The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase
分子名称: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase
著者Ghosh, A, Lima, C.D.
登録日2008-09-07
公開日2008-12-02
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structure of Fcp1, an essential RNA polymerase II CTD phosphatase.
Mol.Cell, 32, 2008
3EF0
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The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase
分子名称: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, TETRAFLUOROALUMINATE ION
著者Ghosh, A, Lima, C.D.
登録日2008-09-07
公開日2008-12-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of Fcp1, an essential RNA polymerase II CTD phosphatase.
Mol.Cell, 32, 2008
1CKO
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BU of 1cko by Molmil
STRUCTURE OF MRNA CAPPING ENZYME IN COMPLEX WITH THE CAP ANALOG GPPPG
分子名称: DIGUANOSINE-5'-TRIPHOSPHATE, MRNA CAPPING ENZYME, ZINC ION
著者Hakansson, K, Wigley, D.B.
登録日1997-09-06
公開日1998-01-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of a complex between a cap analogue and mRNA guanylyl transferase demonstrates the structural chemistry of RNA capping.
Proc.Natl.Acad.Sci.USA, 95, 1998
2HV9
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BU of 2hv9 by Molmil
Encephalitozoon cuniculi mRNA Cap (Guanine-N7) Methyltransferase in complex with sinefungin
分子名称: SINEFUNGIN, mRNA cap guanine-N7 methyltransferase
著者Lima, C.D.
登録日2006-07-27
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mutational Analysis of Encephalitozoon cuniculi mRNA Cap (Guanine-N7) Methyltransferase, Structure of the Enzyme Bound to Sinefungin, and Evidence That Cap Methyltransferase Is the Target of Sinefungin's Antifungal Activity
J.Biol.Chem., 281, 2006
4XQ0
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BU of 4xq0 by Molmil
Structure of fission yeast RNA polymerase II CTD phosphatase Fcp1-R271A bound to beryllium fluoride
分子名称: MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, TETRAETHYLENE GLYCOL
著者Ghosh, A, Lima, C.D.
登録日2015-01-18
公開日2015-03-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.
Rna, 21, 2015
4XPZ
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BU of 4xpz by Molmil
Structure of fission yeast RNA polymerase II CTD phosphatase Fcp1-R271A bound to aluminum fluoride
分子名称: ALUMINUM FLUORIDE, MAGNESIUM ION, RNA polymerase II subunit A C-terminal domain phosphatase, ...
著者Ghosh, A, Lima, C.D.
登録日2015-01-18
公開日2015-03-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Genetic and structural analysis of the essential fission yeast RNA polymerase II CTD phosphatase Fcp1.
Rna, 21, 2015
4PN1
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BU of 4pn1 by Molmil
Structure of S. pombe Pct1 RNA triphosphatase in complex with the Spt5 CTD
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Synthetic peptide, ...
著者Lima, C.D, Doamekpor, S.K.
登録日2014-05-22
公開日2014-11-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Fission yeast RNA triphosphatase reads an Spt5 CTD code.
Rna, 21, 2015
4PZ7
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BU of 4pz7 by Molmil
PCE1 guanylyltransferase
分子名称: GLYCEROL, SULFATE ION, mRNA-capping enzyme subunit alpha
著者Doamekpor, S.K, Lima, C.D.
登録日2014-03-28
公開日2014-06-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.109 Å)
主引用文献How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
Genes Dev., 28, 2014
4PZ8
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BU of 4pz8 by Molmil
PCE1 guanylyltransferase bound to SPT5 CTD
分子名称: SULFATE ION, Transcription elongation factor spt5, mRNA-capping enzyme subunit alpha
著者Doamekpor, S.K, Lima, C.D.
登録日2014-03-28
公開日2014-06-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
Genes Dev., 28, 2014
4PZ6
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PCE1 guanylyltransferase bound to SER2/SER5 phosphorylated RNA pol II CTD
分子名称: DNA-directed RNA polymerase II subunit rpb1, GUANOSINE, mRNA-capping enzyme subunit alpha
著者Doamekpor, S.K, Lima, C.D.
登録日2014-03-28
公開日2014-06-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.
Genes Dev., 28, 2014
2HVQ
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BU of 2hvq by Molmil
Structure of Adenylated full-length T4 RNA Ligase 2
分子名称: Hypothetical 37.6 kDa protein in Gp24-hoc intergenic region, MAGNESIUM ION
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
2HVS
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BU of 2hvs by Molmil
Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 2'-deoxyribonucleotide at the nick
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3', 5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3', ...
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
2HVR
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BU of 2hvr by Molmil
Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 3'-deoxyribonucleotide at the nick
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3', 5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3', ...
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
3RTX
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Crystal structure of mammalian capping enzyme (Mce1) and Pol II CTD complex
分子名称: GUANINE, RNA Polymerase II C-terminal domain, mRNA-capping enzyme
著者Ghosh, A, Lima, C.D.
登録日2011-05-04
公開日2011-06-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural insights to how mammalian capping enzyme reads the CTD code.
Mol.Cell, 43, 2011

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