8DOC
 
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8E1P
 | | Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIP.v4.1-GT1.2gp120, ... | | 著者 | Sarkar, A, Kumar, S, Wilson, I.A. | | 登録日 | 2022-08-11 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.82 Å) | | 主引用文献 | Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.
Cell Rep Med, 4, 2023
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3FTZ
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6XB9
 | | Crystal structure of Azotobacter vinelandii 3-mercaptopropionic acid dioxygenase in complex with 3-hydroxypropionic acid | | 分子名称: | 3-HYDROXY-PROPANOIC ACID, CHLORIDE ION, Cysteine dioxygenase type I protein, ... | | 著者 | Kiser, P.D, Khadka, N, Shi, W, Pierce, B.S. | | 登録日 | 2020-06-05 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure of 3-mercaptopropionic acid dioxygenase with a substrate analog reveals bidentate substrate binding at the iron center.
J.Biol.Chem., 296, 2021
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7WN0
 | | Structure of PfENT1(Y190A) in complex with nanobody 19 | | 分子名称: | Equilibrative nucleoside/nucleobase transporter, nanobody19 | | 著者 | Wang, C, Deng, D, Ren, R.B, Yu, L.Y. | | 登録日 | 2022-01-17 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
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7WN1
 | | Structure of PfNT1(Y190A) in complex with nanobody 48 and inosine | | 分子名称: | Equilibrative nucleoside/nucleobase transporter, INOSINE, nanobody48 | | 著者 | Wang, C, Deng, D, Ren, R.B, Yu, L.Y. | | 登録日 | 2022-01-17 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
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3UA0
 | | N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH Decrease | | 分子名称: | Fibroin heavy chain | | 著者 | He, Y.-X, Zhang, N.-N, Chen, B.-Y, Li, W.-F, Chen, Y.-X, Zhou, C.-Z. | | 登録日 | 2011-10-20 | | 公開日 | 2012-03-28 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH Decrease.
J.Mol.Biol., 418, 2012
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7E7E
 | | The co-crystal structure of ACE2 with Fab | | 分子名称: | Processed angiotensin-converting enzyme 2, ZINC ION, h11B11-Fab | | 著者 | Xiao, J.Y, Zhang, Y. | | 登録日 | 2021-02-26 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants.
Nat Commun, 12, 2021
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7YTJ
 | | Cryo-EM structure of VTC complex | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, INOSITOL HEXAKISPHOSPHATE, PHOSPHATE ION, ... | | 著者 | Guan, Z.Y, Chen, J, Liu, R.W, Chen, Y.K, Xing, Q, Du, Z.M, Liu, Z. | | 登録日 | 2022-08-15 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex.
Nat Commun, 14, 2023
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7U5B
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7CWO
 | | SARS-CoV-2 spike protein RBD and P17 fab complex | | 分子名称: | Spike glycoprotein, heavy chain of P17 Fab, light chain of P17 Fab | | 著者 | Wang, X, Wang, N. | | 登録日 | 2020-08-29 | | 公開日 | 2020-12-16 | | 最終更新日 | 2021-01-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
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7CWL
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7CWM
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7CWN
 | | P17-H014 Fab cocktail in complex with SARS-CoV-2 spike protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Wang, N, Wang, X. | | 登録日 | 2020-08-29 | | 公開日 | 2020-12-16 | | 最終更新日 | 2021-01-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Cell Res., 31, 2021
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8SBG
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8SIJ
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8SL7
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8HIT
 | | Crystal structure of anti-CTLA-4 humanized IgG1 MAb--JS007 in complex with human CTLA-4 | | 分子名称: | Cytotoxic T-lymphocyte protein 4, JS007-VH, JS007-VL | | 著者 | Tan, S, Shi, Y, Wang, Q, Gao, G.F, Guan, J, Chai, Y, Qi, J. | | 登録日 | 2022-11-21 | | 公開日 | 2023-02-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Characterization of the high-affinity anti-CTLA-4 monoclonal antibody JS007 for immune checkpoint therapy of cancer.
Mabs, 15, 2023
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7ML9
 | | The Mpp75Aa1.1 beta-pore-forming protein from Brevibacillus laterosporus | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Insecticidal protein, ... | | 著者 | Rydel, T.J, Zheng, M, Evdokimov, A. | | 登録日 | 2021-04-27 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structural and functional characterization of Mpp75Aa1.1, a putative beta-pore forming protein from Brevibacillus laterosporus active against the western corn rootworm.
Plos One, 16, 2021
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8WQI
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8WQB
 | | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | | 分子名称: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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8WQH
 | | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | | 分子名称: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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8WQG
 | | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1) | | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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8WQF
 | | cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 2) | | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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2HAL
 | | An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors | | 分子名称: | Hepatitis A Protease 3C, N-ACETYL-LEUCYL-PHENYLALANYL-PHENYLALANYL-GLUTAMATE-FLUOROMETHYLKETONE INHIBITOR, N-[(BENZYLOXY)CARBONYL]-L-ALANINE | | 著者 | Yin, J, Cherney, M.M, Bergmann, E.M, James, M.N. | | 登録日 | 2006-06-13 | | 公開日 | 2006-08-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | An Episulfide Cation (Thiiranium Ring) Trapped in the Active Site of HAV 3C Proteinase Inactivated by Peptide-based Ketone Inhibitors.
J.Mol.Biol., 361, 2006
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