8G3R
 
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8G3M
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8G3N
 | | N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with 4 FNI9 Fab molecules | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Dang, H, Snell, G. | | 登録日 | 2023-02-08 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
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8G40
 | | N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 3 FNI19 Fab molecules | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Dang, H.V, Snell, G. | | 登録日 | 2023-02-08 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
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8G3P
 | | N2 neuraminidase of A/Hong_Kong/2671/2019 in complex with 4 FNI9 Fab molecules | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Dang, H.V, Snell, G. | | 登録日 | 2023-02-08 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-06-28 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
Nature, 618, 2023
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5ZXI
 | | Co-crystal structure of an Inhibitor in complex with human PPARdelta LBD | | 分子名称: | 6-[2-({2-[4-(furan-2-yl)phenyl]-5-methyl-1H-imidazol-1-yl}methyl)phenoxy]hexanoic acid, Peroxisome proliferator-activated receptor delta | | 著者 | Rani, S.T, Laxminarasimhan, A, Senaiar, R.S, Krishnamurthy, N. | | 登録日 | 2018-05-21 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Selective PPAR delta Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD).
ACS Med Chem Lett, 9, 2018
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6XXY
 | | Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase in complex with O-isobutenyl oxalylhydroxamate. | | 分子名称: | 2-(2-methylprop-2-enoxyamino)-2-oxidanylidene-ethanoic acid, 3-isopropylmalate dehydrogenase, MAGNESIUM ION, ... | | 著者 | Miggiano, R, Rossi, F, Martignon, S, Rizzi, M. | | 登録日 | 2020-01-28 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate.
Biochem.Biophys.Res.Commun., 524, 2020
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6FE0
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6FE2
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6FE1
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5DE9
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6G98
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6G9U
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8EZR
 | | Crystal structure of the HipS(Lp)-HipT(Lp) complex from Legionella pneumophila, native protein | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, HipS(Lp), ... | | 著者 | Stogios, P.J, Skarina, T, Michalska, K, Di Leo, R, Lin, J, Ensminger, A, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-11-01 | | 公開日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of the HipS(Lp)-HipT(Lp) complex from Legionella pneumophila, native protein
To Be Published
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8EZT
 | | Crystal structure of HipB(Lp) from Legionella pneumophila | | 分子名称: | CHLORIDE ION, HipB(Lp) | | 著者 | Stogios, P.J, Skarina, T, Di Leo, R, Lin, J, Ensminger, A, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-11-01 | | 公開日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Crystal structure of HipB(Lp) from Legionella pneumophila
To Be Published
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8EZS
 | | Crystal structure of the HipS(Lp)-HipT(Lp) complex from Legionella pneumophila, Sel-met protein | | 分子名称: | CHLORIDE ION, HipS(Lp), HipT(Lp) | | 著者 | Stogios, P.J, Skarina, T, Michalska, K, Di Leo, R, Lin, J, Ensminger, A, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-11-01 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Crystal structure of the HipS(Lp)-HipT(Lp) complex from Legionella pneumophila, Sel-met protein
To Be Published
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7QUR
 | | SARS-CoV-2 Spike with ethylbenzamide-tri-iodo Siallyllactose, C3 symmetry | | 分子名称: | 2,3,5-tris(iodanyl)benzamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Naismith, J.H, Yang, Y, Liu, J.W. | | 登録日 | 2022-01-18 | | 公開日 | 2022-06-01 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | | 主引用文献 | Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Science, 377, 2022
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7QUS
 | | SARS-CoV-2 Spike, C3 symmetry | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | | 著者 | Naismith, J.H, Yang, Y, Liu, J.W. | | 登録日 | 2022-01-18 | | 公開日 | 2022-06-08 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | | 主引用文献 | Pathogen-sugar interactions revealed by universal saturation transfer analysis.
Science, 377, 2022
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6SNC
 | | crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LNO1 Heavy Chain, ... | | 著者 | Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W. | | 登録日 | 2019-08-23 | | 公開日 | 2019-11-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 26, 2019
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6TOU
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6SNE
 | | crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LN01 heavy chain, ... | | 著者 | Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W. | | 登録日 | 2019-08-23 | | 公開日 | 2019-11-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 26, 2019
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6SND
 | | crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide | | 分子名称: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | 著者 | Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W. | | 登録日 | 2019-08-23 | | 公開日 | 2019-11-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 26, 2019
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7UPY
 | | An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F. | | 登録日 | 2022-04-18 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion.
Sci Immunol, 7, 2022
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8UP1
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8URE
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