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4M8M
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BU of 4m8m by Molmil
Crystal structure of the active dimer of zebrafish PlexinC1 cytoplasmic region
分子名称: GCN4 coiled-coil fused zebrafish PlexinC1
著者Wang, Y, Pascoe, H.G, Zhang, X.
登録日2013-08-13
公開日2013-10-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.307 Å)
主引用文献Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin.
Elife, 2, 2013
4LGD
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BU of 4lgd by Molmil
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ras association domain family member 5, ...
著者Luo, X, Ni, L, Tomchick, D.R.
登録日2013-06-27
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5.
Structure, 21, 2013
4O67
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BU of 4o67 by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with GAMP
分子名称: Cyclic GMP-AMP synthase, ZINC ION, cGAMP
著者Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
登録日2013-12-20
公開日2014-02-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.444 Å)
主引用文献The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
4O68
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BU of 4o68 by Molmil
Structure of human cyclic GMP-AMP synthase (cGAS)
分子名称: Cyclic GMP-AMP synthase, ZINC ION
著者Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
登録日2013-12-20
公開日2014-02-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.436 Å)
主引用文献The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
4O69
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BU of 4o69 by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion
分子名称: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION
著者Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
登録日2013-12-20
公開日2014-02-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.252 Å)
主引用文献The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
4O6A
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BU of 4o6a by Molmil
Mouse cyclic GMP-AMP synthase (cGAS) in complex with DNA
分子名称: Cyclic GMP-AMP synthase, DNA1, DNA2, ...
著者Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
登録日2013-12-20
公開日2014-02-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.859 Å)
主引用文献The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
6AO5
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BU of 6ao5 by Molmil
Crystal structure of human MST2 in complex with SAV1 SARAH domain
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein salvador homolog 1, ...
著者Tomchick, D.R, Luo, X, Ni, L.
登録日2017-08-15
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.955 Å)
主引用文献SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.
Elife, 6, 2017
6N1Z
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BU of 6n1z by Molmil
Importin-9 bound to H2A-H2B
分子名称: Histone H2A, Histone H2B 1.1, Importin-9
著者Tomchick, D.R, Chook, Y.M, Padavannil, A.
登録日2018-11-12
公開日2019-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Importin-9 wraps around the H2A-H2B core to act as nuclear importer and histone chaperone.
Elife, 8, 2019
6URQ
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BU of 6urq by Molmil
Complex structure of human poly-ADP-ribosyltransferase TNKS1 ARC2-ARC3 and P antigen family member 4 (PAGE4)
分子名称: GLYCEROL, P antigen family member 4, Poly [ADP-ribose] polymerase tankyrase-1, ...
著者Zheng, Y, Koirala, S, Miller, D, Potts, P.R.
登録日2019-10-24
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Tissue-Specific Regulation of the Wnt/ beta-Catenin Pathway by PAGE4 Inhibition of Tankyrase.
Cell Rep, 32, 2020
6VII
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BU of 6vii by Molmil
Crystal structure of mouse RABL3 in complex with GTPgammaS
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rab-like protein 3
著者Su, L, Tomchick, D.R, Beutler, B.
登録日2020-01-13
公開日2020-04-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
Proc.Natl.Acad.Sci.USA, 117, 2020
3N5A
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BU of 3n5a by Molmil
Synaptotagmin-7, C2B-domain, calcium bound
分子名称: CALCIUM ION, Synaptotagmin-7
著者Tomchick, D.R, Rizo, J, Craig, T.K.
登録日2010-05-24
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.441 Å)
主引用文献Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7.
Plos One, 5, 2010
5DHF
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BU of 5dhf by Molmil
Crystal Structure of hRio2 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: CHLORIDE ION, Exportin-1, GLYCEROL, ...
著者Fung, H.Y, Chook, Y.M.
登録日2015-08-30
公開日2015-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.285 Å)
主引用文献Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DH9
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BU of 5dh9 by Molmil
Crystal Structure of PKI NES Flip Mutant Peptide in complex with CRM1-Ran-RanBP1
分子名称: Engineered Nuclear Export Signal Peptide (PKINES-Flip3 mutant), Exportin-1, GLYCEROL, ...
著者Fung, H.Y, Chook, Y.M.
登録日2015-08-30
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DHA
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BU of 5dha by Molmil
Crystal Structure of CPEB4 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1
分子名称: Engineered Nuclear Export Signal Peptide (CPEB4 NES reverse mutant), Exportin-1, GLYCEROL, ...
著者Fung, H.Y, Chook, Y.M.
登録日2015-08-30
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DIF
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BU of 5dif by Molmil
Crystal Structure of CPEB4 NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: CHLORIDE ION, Cytoplasmic polyadenylation element-binding protein 4, Exportin-1, ...
著者Fung, H.Y, Chook, Y.M.
登録日2015-08-31
公開日2015-09-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.092 Å)
主引用文献Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5DI9
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BU of 5di9 by Molmil
Crystal Structure of hRio2 NES Reverse Mutant Peptide in complex with CRM1-Ran-RanBP1
分子名称: CHLORIDE ION, Engineered Nuclear Export Signal Peptide (hRio2 NES reverse mutant), Exportin-1, ...
著者Fung, H.Y, Chook, Y.M.
登録日2015-08-31
公開日2015-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural determinants of nuclear export signal orientation in binding to exportin CRM1.
Elife, 4, 2015
5E6P
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BU of 5e6p by Molmil
PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex
分子名称: Plexin-B2, Rho guanine nucleotide exchange factor 11
著者Pascoe, H.G, Zhang, X.
登録日2015-10-10
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.215 Å)
主引用文献Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Proc.Natl.Acad.Sci.USA, 112, 2015
4M63
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BU of 4m63 by Molmil
Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ...
著者Tomchick, D.R, Zahm, J.A, Rosen, M.K.
登録日2013-08-08
公開日2013-10-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.748 Å)
主引用文献The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
6X2W
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BU of 6x2w by Molmil
Crystal Structure of PKINES peptide bound to CRM1(E571K)
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Baumhardt, J.M.
登録日2020-05-21
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2U
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BU of 6x2u by Molmil
Crystal Structure of PKINES peptide bound to CRM1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Baumhardt, J.M.
登録日2020-05-21
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2M
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BU of 6x2m by Molmil
Crystal Structure of unliganded CRM1-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Baumhardt, J.M.
登録日2020-05-20
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2P
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Crystal Structure of the Mek1NES peptide bound to CRM1
分子名称: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ...
著者Baumhardt, J.M.
登録日2020-05-20
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2V
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Crystal Structure of PKI(DE)NES peptide bound to CRM1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Baumhardt, J.M.
登録日2020-05-21
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.822 Å)
主引用文献Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2X
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Crystal Structure of Mek1NES peptide bound to CRM1(E571K)
分子名称: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ...
著者Baumhardt, J.M.
登録日2020-05-21
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.458 Å)
主引用文献Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020
6X2O
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Crystal Structure of unliganded CRM1(E571K)-Ran-RanBP1
分子名称: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
著者Baumhardt, J.M.
登録日2020-05-20
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.551 Å)
主引用文献Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation.
Mol.Biol.Cell, 31, 2020

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