6ND5
 
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with chloramphenicol and bound to mRNA and A-, P-, and E-site tRNAs at 2.60A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Svetlov, M.S, Plessa, E, Chen, C.-W, Bougas, A, Krokidis, M.G, Dinos, G.P, Polikanov, Y.S. | | 登録日 | 2018-12-13 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition.
RNA, 25, 2019
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4AFQ
 | | Human Chymase - Fynomer Complex | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHYMASE, CITRATE ANION, ... | | 著者 | Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M. | | 登録日 | 2012-01-23 | | 公開日 | 2012-07-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain.
Mabs, 4, 2012
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6RB7
 | | Ruminococcus gnavus sialic acid aldolase catalytic lysine mutant | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BICINE, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Owen, C.D, Bell, A, Juge, N, Walsh, M.A. | | 登録日 | 2019-04-09 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.
Nat Microbiol, 4, 2019
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6ZU1
 | | E. coli 70S-RNAP expressome complex in uncoupled state 2 | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Webster, M.W, Takacs, M, Weixlbaumer, A. | | 登録日 | 2020-07-21 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
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4ARA
 | | Mus musculus Acetylcholinesterase in complex with (R)-C5685 at 2.5 A resolution. | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(DIMETHYLAMINO)-N-{[(2R)-1-ETHYLPYRROLIDIN-2-YL]METHYL}-2-METHOXY-5-NITROBENZAMIDE, ... | | 著者 | Berg, L, Niemiec, M.S, Qian, W, Andersson, C.D, WittungStafshede, P, Ekstrom, F, Linusson, A. | | 登録日 | 2012-04-23 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Similar But Different: Thermodynamic and Structural Characterization of a Pair of Enantiomers Binding to Acetylcholinesterase.
Angew.Chem.Int.Ed.Engl., 51, 2012
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5N4H
 | | Crystal structure of the D109N mutant of the mouse alpha-Dystroglycan N-terminal region | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Dystroglycan | | 著者 | Cassetta, A, Covaceuszach, S, Brancaccio, A, Sciandra, F, Bozzi, M, Bigotti, M.G, Konarev, P.V. | | 登録日 | 2017-02-10 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | The effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of alpha-dystroglycan.
PLoS ONE, 12, 2017
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5N57
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6NSW
 | | X-ray reduced Catalase 3 From N.Crassa in Cpd I state (0.135 MGy) | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Catalase-3, ... | | 著者 | Zarate-Romero, A, Rudino-Pinera, E, Stojanoff, V. | | 登録日 | 2019-01-25 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | X-ray driven reduction of Cpd I of Catalase-3 from N. crassa reveals differential sensitivity of active sites and formation of ferrous state.
Arch.Biochem.Biophys., 666, 2019
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2IDA
 | | Solution NMR Structure of Protein RPA1320 from Rhodopseudomonas Palustris. Northeast Structural Genomics Consortium Target RpT3; Ontario Center for Structural Proteomics Target RP1313. | | 分子名称: | Hypothetical protein, ZINC ION | | 著者 | Lemak, A, Yee, A, Lukin, J.A, Karra, M, Gutmanas, A, Guido, V, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-09-14 | | 公開日 | 2006-10-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of RPA1320
To be Published
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5N5U
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5CZ2
 | | Crystal structure of a two-domain fragment of MMTV integrase | | 分子名称: | MAGNESIUM ION, Pol polyprotein, ZINC ION | | 著者 | Cook, N, Ballandras-Colas, A, Engelman, A, Cherepanov, P. | | 登録日 | 2015-07-31 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function.
Nature, 530, 2016
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6NBG
 | | 2.05 Angstrom Resolution Crystal Structure of Hypothetical Protein KP1_5497 from Klebsiella pneumoniae. | | 分子名称: | CHLORIDE ION, Glucosamine-6-phosphate deaminase, PHOSPHATE ION | | 著者 | Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2018-12-07 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-06-14 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae.
Microbiol Resour Announc, 12, 2023
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8F9O
 | | Dog sialic acid esterase (SIAE) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sialic acid acetylesterase, ... | | 著者 | Ide, D, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2022-11-24 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Dog sialic acid esterase (SIAE)
To Be Published
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6TCU
 | | Glycogen synthase kinase-3 beta (GSK3b) in complex with ligand 1 | | 分子名称: | 5-[2,3-bis(fluoranyl)phenyl]-~{N}-[[1-(2-methoxyethyl)piperidin-4-yl]methyl]-1~{H}-indazole-3-carboxamide, ACETATE ION, Glycogen synthase kinase-3 beta | | 著者 | Lammens, A, Krapp, S, Buonfiglio, R, Ombrato, R. | | 登録日 | 2019-11-06 | | 公開日 | 2020-09-16 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Optimization of Indazole-Based GSK-3 Inhibitors with Mitigated hERG Issue andIn VivoActivity in a Mood Disorder Model.
Acs Med.Chem.Lett., 11, 2020
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8F9Q
 | | Guinea pig sialic acid esterase (SIAE) | | 分子名称: | Sialic acid acetylesterase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ide, D, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2022-11-24 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Guinea pig sialic acid esterase (SIAE)
To Be Published
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8F9P
 | | Dog sialic acid esterase (SIAE) inactive mutant S128A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Ide, D, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2022-11-24 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Dog sialic acid esterase (SIAE) inactive mutant S128A
To Be Published
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8F9R
 | | Rabbit sialic acid esterase (SIAE) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sialic acid acetylesterase, ... | | 著者 | Ide, D, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2022-11-24 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Rabbit sialic acid esterase (SIAE)
To Be Published
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8FDV
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1LTU
 | | CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM, APO (NO IRON BOUND) STRUCTURE | | 分子名称: | PHENYLALANINE-4-HYDROXYLASE | | 著者 | Erlandsen, H, Kim, J.Y, Patch, M.G, Han, A, Volner, A, Abu-Omar, M.M, Stevens, R.C. | | 登録日 | 2002-05-20 | | 公開日 | 2002-07-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
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8FJ7
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8FAQ
 | | Structure of Hemagglutinin from Influenza A/Victoria/22/2020 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | | 著者 | Hernandez Garcia, A, Lei, R. | | 登録日 | 2022-11-28 | | 公開日 | 2024-06-19 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.035 Å) | | 主引用文献 | Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin.
Nat Commun, 15, 2024
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1CY2
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8FQJ
 | | LSD1-CoREST in complex with T14, short soaking | | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2S,3R,4R)-2,3,4-trihydroxy-5-[(1R,3S,3aS,13R)-1-hydroxy-10,11-dimethyl-3-{4-[(5-methyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl}-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]pentyl dihydrogen diphosphate | | 著者 | Caroli, J, Mattevi, A. | | 登録日 | 2023-01-06 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
To be published
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8FAW
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6T5Z
 | | Crystal structure of an AA10 LPMO from Photorhabdus luminescens | | 分子名称: | COPPER (II) ION, Chitin-binding type-4 domain-containing protein | | 著者 | Munzone, A, El Kerdi, B, Reglier, M, Royant, A, Simaan, A.J, Decroos, C. | | 登録日 | 2019-10-17 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.60000312 Å) | | 主引用文献 | Characterization of a bacterial copper-dependent lytic polysaccharide monooxygenase with an unusual second coordination sphere.
Febs J., 287, 2020
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