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2BEV
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BU of 2bev by Molmil
Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch
分子名称: 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, C2-1-HYDROXY-2-METHYL-BUTYL-THIAMIN DIPHOSPHATE, ...
著者Machius, M, Wynn, R.M, Chuang, J.L, Tomchick, D.R, Brautigam, C.A, Chuang, D.T.
登録日2004-11-30
公開日2006-02-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase.
Structure, 14, 2006
4XHF
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BU of 4xhf by Molmil
Crystal structure of Shewanella oneidensis NqrC
分子名称: FLAVIN MONONUCLEOTIDE, Na-translocating NADH-quinone reductase subunit C NqrC, SODIUM ION
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2015-01-05
公開日2015-12-16
最終更新日2016-03-16
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm.
Microbiologyopen, 5, 2016
4XDU
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BU of 4xdu by Molmil
Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein,a bifunctional FMN transferase/FAD pyrophosphatase, N55Y mutant, ADP bound form
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2014-12-20
公開日2015-10-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein.
Mbio, 6, 2015
4XGX
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BU of 4xgx by Molmil
Crystal structure of Escherichia coli Flavin trafficking protein, an FMN transferase, Y60N mutant, ADP-inhibited
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FAD:protein FMN transferase, ...
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2015-01-02
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm.
Microbiologyopen, 5, 2016
4XDR
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BU of 4xdr by Molmil
Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, a bifunctional FMN transferase/FAD pyrophosphatase, D284A mutant, ADN bound form
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE, ...
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2014-12-19
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein.
Mbio, 6, 2015
4XGW
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BU of 4xgw by Molmil
Crystal structure of Escherichia coli Flavin trafficking protein, an FMN transferase, E169K mutant
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, FAD:protein FMN transferase, ...
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2015-01-02
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.747 Å)
主引用文献Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm.
Microbiologyopen, 5, 2016
4ZJC
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BU of 4zjc by Molmil
Structures of the human OX1 orexin receptor bound to selective and dual antagonists
分子名称: OLEIC ACID, [5-(2-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]{(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]pyrrolidin-1-yl}methanone, human OX1R fusion protein to P.abysii glycogen synthase
著者Yin, J, Brautigam, C.A, Shao, Z, Clark, L, Harrell, C.M, Gotter, A.L, Coleman, P.J, Renger, J.J, Rosenbaum, D.M.
登録日2015-04-29
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.832 Å)
主引用文献Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.
Nat.Struct.Mol.Biol., 23, 2016
4ZJ8
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BU of 4zj8 by Molmil
Structures of the human OX1 orexin receptor bound to selective and dual antagonists
分子名称: OLEIC ACID, [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone, human OX1R fusion protein to P.abysii glycogen synthase
著者Yin, J, Brautigam, C.A, Shao, Z, Clark, L, Harrell, C.M, Gotter, A.L, Coleman, P, Renger, J.J, Rosenbaum, D.M.
登録日2015-04-29
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.
Nat.Struct.Mol.Biol., 23, 2016
4XGV
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BU of 4xgv by Molmil
Crystal structure of Escherichia coli Flavin trafficking protein, an FMN transferase
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2015-01-02
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.883 Å)
主引用文献Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm.
Microbiologyopen, 5, 2016
4XDT
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BU of 4xdt by Molmil
Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, a bifunctional FMN transferase/FAD pyrophosphatase, N55Y mutant, FAD bound form
分子名称: 1,2-ETHANEDIOL, ACETATE ION, FAD:protein FMN transferase, ...
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2014-12-19
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.452 Å)
主引用文献Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein.
Mbio, 6, 2015
2O6D
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BU of 2o6d by Molmil
Structure of native rTp34 from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, CHLORIDE ION, ...
著者Machius, M, Brautigam, C.A, Deka, R.K, Tomchick, D.R, Lumpkins, S.B, Norgard, M.V.
登録日2006-12-07
公開日2006-12-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2O6F
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BU of 2o6f by Molmil
Structure of metal- free rTp34 from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, CHLORIDE ION, ...
著者Machius, M, Brautigam, C.A, Deka, R.K, Tomchick, D.R, Lumpkins, S.B, Norgard, M.V.
登録日2006-12-07
公開日2006-12-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2O6C
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BU of 2o6c by Molmil
Structure of selenomethionyl rTp34 from Treponema pallidum
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, CHLORIDE ION, ...
著者Machius, M, Brautigam, C.A, Deka, R.K, Tomchick, D.R, Lumpkins, S.B, Norgard, M.V.
登録日2006-12-07
公開日2006-12-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2OIX
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BU of 2oix by Molmil
Xanthomonas XopD C470A Mutant
分子名称: Xanthomonas outer protein D
著者Chosed, R, Tomchick, D.R, Brautigam, C.A, Machius, M, Orth, K.
登録日2007-01-11
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases.
J.Biol.Chem., 282, 2007
2O6E
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BU of 2o6e by Molmil
Structure of native rTp34 from Treponema pallidum from zinc-soaked crystals
分子名称: 1,2-ETHANEDIOL, 34 kDa membrane antigen, CHLORIDE ION, ...
著者Machius, M, Brautigam, C.A, Deka, R.K, Tomchick, D.R, Lumpkins, S.B, Norgard, M.V.
登録日2006-12-07
公開日2006-12-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin.
J.Biol.Chem., 282, 2007
2OIV
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BU of 2oiv by Molmil
Structural Analysis of Xanthomonas XopD Provides Insights Into Substrate Specificity of Ubiquitin-like Protein Proteases
分子名称: PHOSPHATE ION, Xanthomonas outer protein D
著者Chosed, R, Tomchick, D.R, Brautigam, C.A, Machius, M, Orth, K.
登録日2007-01-11
公開日2007-05-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases.
J.Biol.Chem., 282, 2007
5WC2
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BU of 5wc2 by Molmil
Crystal Structure of ADP-bound human TRIP13
分子名称: ADENOSINE-5'-DIPHOSPHATE, Pachytene checkpoint protein 2 homolog
著者Jeong, B.-C, Luo, X.
登録日2017-06-29
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing.
Nat Commun, 8, 2017
7CYL
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BU of 7cyl by Molmil
Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L)
分子名称: RNA-binding protein FUS, Transportin-1
著者Yoshizawa, T, Chook, Y.M.
登録日2020-09-03
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
Sci Rep, 11, 2021
4U3J
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BU of 4u3j by Molmil
TOG2:alpha/beta-tubulin complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein STU2, ...
著者Ayaz, P, Rice, L.M.
登録日2014-07-22
公開日2014-08-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献A tethered delivery mechanism explains the catalytic action of a microtubule polymerase.
Elife, 3, 2014
6VIK
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BU of 6vik by Molmil
Crystal structure of mouse xm RABL3 in complex with GTPgammsS
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rab-like protein 3
著者Su, L, Tomchick, D.R, Beutler, B.
登録日2020-01-13
公開日2020-04-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VIH
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BU of 6vih by Molmil
The ligand-free structure of mouse RABL3
分子名称: Rab-like protein 3
著者Su, L, Tomchick, D.R, Beutler, B.
登録日2020-01-13
公開日2020-04-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.993 Å)
主引用文献Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VIJ
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BU of 6vij by Molmil
Crystal structure of mouse RABL3 in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rab-like protein 3
著者Su, L, Tomchick, D.R, Beutler, B.
登録日2020-01-13
公開日2020-04-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.
Proc.Natl.Acad.Sci.USA, 117, 2020
7TWD
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BU of 7twd by Molmil
Structure of AAGAB C-terminal dimerization domain
分子名称: Alpha- and gamma-adaptin-binding protein p34, PHOSPHATE ION
著者Tian, Y, Yin, Q.
登録日2022-02-07
公開日2023-01-18
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Oligomer-to-monomer transition underlies the chaperone function of AAGAB in AP1/AP2 assembly.
Proc.Natl.Acad.Sci.USA, 120, 2023
8SGH
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BU of 8sgh by Molmil
Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS
分子名称: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, Transportin-1
著者Gonzalez, A, Fung, H.Y.J, Chook, Y.M.
登録日2023-04-12
公開日2023-06-14
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献A new Karyopherin-beta 2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders.
Structure, 31, 2023
4LG4
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BU of 4lg4 by Molmil
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
分子名称: GLYCEROL, Serine/threonine-protein kinase 3
著者Luo, X, Ni, L, Tomchick, D.R.
登録日2013-06-27
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5.
Structure, 21, 2013

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